2020
Incident HIV among pregnant and breast-feeding women in sub-Saharan Africa: a systematic review and meta-analysis.
Graybill LA, Kasaro M, Freeborn K, Walker JS, Poole C, Powers KA, Mollan KR, Rosenberg NE, Vermund SH, Mutale W, Chi BH. Incident HIV among pregnant and breast-feeding women in sub-Saharan Africa: a systematic review and meta-analysis. AIDS 2020, 34: 761-776. PMID: 32167990, PMCID: PMC7275092, DOI: 10.1097/qad.0000000000002487.Peer-Reviewed Original ResearchMeSH KeywordsAfrica South of the SaharaBreast FeedingFemaleHIV InfectionsHIV SeropositivityHumansPostpartum PeriodPregnancyPregnancy Complications, InfectiousConceptsBreast-feeding womenMaternal HIV incidenceHIV incidenceHIV acquisitionIncidence rateHIV preventionSystematic reviewHigh HIV incidencePartner's HIV statusHIV incidence ratesCombination HIV preventionNonpregnant periodsIncident HIVTreatment landscapeHIV statusSaharan AfricaElevated riskSummary estimatesRelevant conferencesIncidenceAverage incidenceLimited evidenceWomenCalendar timePrevention
2019
Low awareness of influenza vaccination among pregnant women and their obstetricians: a population-based survey in Beijing, China
Wang J, Sun D, Abudusaimaiti X, Vermund SH, Li D, Hu Y. Low awareness of influenza vaccination among pregnant women and their obstetricians: a population-based survey in Beijing, China. Human Vaccines & Immunotherapeutics 2019, 15: 2637-2643. PMID: 30932729, PMCID: PMC6930072, DOI: 10.1080/21645515.2019.1596713.Peer-Reviewed Original ResearchConceptsAntenatal influenza vaccinationInfluenza vaccinationPregnant womenNational Health CommissionMore high-quality trialsHigh-quality trialsBenefits of vaccinationPopulation-based surveyHistory of vaccinationChina National Health CommissionPregnant patientsAntenatal clinicInfluenza vaccineInfluenza knowledgeSame clinicVaccinationObstetriciansPregnancyHealth CommissionWomenClinicLow awarenessGovernment recommendationsRelevant evidenceQuestionnaire
2018
Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis
Zhang X, Yu Y, Yang H, Xu H, Vermund SH, Liu K. Surveillance of Maternal Syphilis in China: Pregnancy Outcomes and Determinants of Congenital Syphilis. Medical Science Monitor 2018, 24: 7727-7735. PMID: 30370903, PMCID: PMC6216479, DOI: 10.12659/msm.910216.Peer-Reviewed Original ResearchConceptsAdverse pregnancy outcomesPregnancy outcomesCongenital syphilisPregnant womenFirst antenatal care visitEligible pregnant womenPrevention of motherAntenatal care visitsIndependent risk factorMultivariable regression analysisLogistic regression analysisRegression analysisChild transmissionMaternal syphilisAntenatal careCare visitsNeonatal asphyxiaNeonatal deathFirst trimesterRisk womenAntibody titersAntenatal testingEpidemiological characteristicsRisk factorsSyphilis diagnosis“I will leave the baby with my mother”: Long‐distance travel and follow‐up care among HIV‐positive pregnant and postpartum women in South Africa
Clouse K, Fox MP, Mongwenyana C, Motlhatlhedi M, Buthelezi S, Bokaba D, Norris SA, Bassett J, Lurie MN, Aronoff DM, Vermund SH. “I will leave the baby with my mother”: Long‐distance travel and follow‐up care among HIV‐positive pregnant and postpartum women in South Africa. Journal Of The International AIDS Society 2018, 21: e25121. PMID: 30027665, PMCID: PMC6053484, DOI: 10.1002/jia2.25121.Peer-Reviewed Original ResearchMeSH KeywordsAdultAftercareFamilyFemaleHealth Services AccessibilityHIV InfectionsHumansInfantInfant, NewbornMothersPatient Acceptance of Health CarePostpartum PeriodPregnancyPregnancy Complications, InfectiousSouth AfricaTravelConceptsSouth AfricaNine provincesMotivation of travelLong-distance travelSouth Africa's nine provincesPostpartum womenPeripartum periodGreater JohannesburgSouth African provincesCare of familiesFragmented healthcare systemContinuity of HIVHIV-positive womenMobile populationsTravel patternsUrban African settingAfrican provincesJohannesburgHealthcare accessFrequent travelMedian durationMedian ageDiverse clinicsFrequent mobilityGauteng Province
2017
Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa
Clouse K, Vermund SH, Maskew M, Lurie MN, MacLeod W, Malete G, Carmona S, Sherman G, Fox MP. Mobility and Clinic Switching Among Postpartum Women Considered Lost to HIV Care in South Africa. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 74: 383-389. PMID: 28225717, PMCID: PMC5324708, DOI: 10.1097/qai.0000000000001284.Peer-Reviewed Original ResearchConceptsHIV careNational Health Laboratory Service databaseLow CD4 cell countsNational Antiretroviral Therapy ProgramCD4 cell countObservational cohort studyAntiretroviral therapy programsAntiretroviral therapyCohort studyPostpartum womenPublic clinicsService databaseCell countTherapy programCareWomenLTFUClinicOne-thirdDaysPatientsPregnancyTherapy
2016
Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria
Boehmer A, Audet CM, Blevins M, Gebi UI, Wester CW, Vermund SH, Aliyu MH. Patient and Provider Satisfaction With a Comprehensive Strategy to Improve Prevention of Mother-to-Child HIV Transmission Services in Rural Nigeria. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2016, 72: s117-s123. PMID: 27355498, PMCID: PMC5113240, DOI: 10.1097/qai.0000000000001058.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsComprehensive Health CareFemaleHIV InfectionsHumansInfant, NewbornInfectious Disease Transmission, VerticalJob SatisfactionNigeriaPatient SatisfactionPregnancyPregnancy Complications, InfectiousConceptsPrevention of motherProvider satisfactionPatient satisfactionWeeks postpartumControl armIntervention sitesChild HIV transmission servicesChild HIV transmission rateMother-infant careCD4 cell countHIV transmission ratesCluster-randomized trialTotal patient satisfactionAntiretroviral therapyHIV careChild transmissionPrescribed treatmentClinician satisfactionHealth personnelLower cadre workersCell countHealth problemsMale involvementProvider rolesProviders' abilityIntegrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central Nigeria: a cluster-randomised controlled trial
Aliyu MH, Blevins M, Audet CM, Kalish M, Gebi UI, Onwujekwe O, Lindegren ML, Shepherd BE, Wester CW, Vermund SH. Integrated prevention of mother-to-child HIV transmission services, antiretroviral therapy initiation, and maternal and infant retention in care in rural north-central Nigeria: a cluster-randomised controlled trial. The Lancet HIV 2016, 3: e202-e211. PMID: 27126487, PMCID: PMC4852280, DOI: 10.1016/s2352-3018(16)00018-7.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAnti-HIV AgentsCD4 Lymphocyte CountDelivery of Health Care, IntegratedEarly Intervention, EducationalFamilyFemaleHIV InfectionsHumansInfantInfectious Disease Transmission, VerticalMaleMothersNevirapineNigeriaPregnancyPregnancy Complications, InfectiousPrenatal CareRural PopulationYoung AdultConceptsChild HIV transmissionAntiretroviral therapyStandard of careRural North-Central NigeriaWeeks post partumIntervention groupAntiretroviral prophylaxisEligible womenHIV statusHIV transmissionSecondary level health care facilitiesChild HIV transmission servicesClinical stage 1 diseasePost partumEunice Kennedy Shriver National InstituteMedian CD4 countPMTCT service deliveryAntiretroviral therapy initiationCD4 cell countPrevention of motherStage 1 diseaseUnknown HIV statusElimination of motherNorth Central NigeriaEarly infant diagnosisEngagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique
Audet CM, Blevins M, Chire YM, Aliyu MH, Vaz LM, Antonio E, Alvim F, Bechtel R, Wester CW, Vermund SH. Engagement of Men in Antenatal Care Services: Increased HIV Testing and Treatment Uptake in a Community Participatory Action Program in Mozambique. AIDS And Behavior 2016, 20: 2090-2100. PMID: 26906021, PMCID: PMC4995150, DOI: 10.1007/s10461-016-1341-x.Peer-Reviewed Original ResearchConceptsAntenatal careHIV testingPregnant womenProvider-initiated counselingAntenatal care servicesAntiretroviral therapy servicesPre-post intervention designUptake of ARTTraditional birth attendantsMale engagementCommunity health agentsRate of testingANC servicesTreatment uptakeBirth attendantsService uptakePartner's pregnancyCare servicesTherapy servicesHealth agentsTreatment acceptabilityMale partnersSimilar interventionsMale championsPregnancy
2015
Achieving Pregnancy Safely in HIV-Affected Individuals and Couples
Mmeje O, Njoroge B, Cohen CR, Temmerman M, Vermund SH, van der Poel S. Achieving Pregnancy Safely in HIV-Affected Individuals and Couples. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2015, 70: e155-e159. PMID: 26334740, PMCID: PMC10767706, DOI: 10.1097/qai.0000000000000814.Peer-Reviewed Original ResearchScreening for Sexually Transmitted Infections in Antenatal Care Is Especially Important Among HIV-Infected Women
Vermund SH. Screening for Sexually Transmitted Infections in Antenatal Care Is Especially Important Among HIV-Infected Women. Sexually Transmitted Diseases 2015, 42: 566-568. PMID: 26372928, PMCID: PMC5398314, DOI: 10.1097/olq.0000000000000342.Peer-Reviewed Original ResearchMeSH KeywordsChlamydia InfectionsFemaleGonorrheaHIV SeropositivityHumansInfectious Disease Transmission, VerticalMothersPost-Exposure ProphylaxisPregnancyPregnancy Complications, InfectiousPregnant Women
2014
Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China
Wang AL, Qiao YP, Wang LH, Fang LW, Wang F, Jin X, Qiu J, Wang XY, Wang Q, Wu JL, Vermund SH, Song L. Integrated prevention of mother-to-child transmission for human immunodeficiency virus, syphilis and hepatitis B virus in China. Bulletin Of The World Health Organization 2014, 93: 52-56. PMID: 25558108, PMCID: PMC4271682, DOI: 10.2471/blt.14.139626.Peer-Reviewed Original ResearchMeSH KeywordsChinaFemaleHepatitis BHIV InfectionsHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousPrenatal CareSyphilisSyphilis, CongenitalConceptsHuman immunodeficiency virusHepatitis B virusAntenatal care clinicsChild transmissionPregnant womenPMTCT servicesCare clinicsImmunodeficiency virusB virusChild transmission effortsRate of maternalChild health clinicsChild health servicesRoutine maternalHBV infectionInfected womenCongenital syphilisHIV programsGeneral HospitalHealth clinicsLive birthsFurther interventionStandardized preventionSyphilis transmissionHealth services
2013
Combination Prevention: New Hope for Stopping the Epidemic
Vermund SH, Hayes RJ. Combination Prevention: New Hope for Stopping the Epidemic. Current HIV/AIDS Reports 2013, 10: 169-186. PMID: 23456730, PMCID: PMC3642362, DOI: 10.1007/s11904-013-0155-y.Peer-Reviewed Original ResearchMeSH KeywordsAfrica South of the SaharaAnti-HIV AgentsFemaleHealth Knowledge, Attitudes, PracticeHealth PolicyHealth Services AccessibilityHIV InfectionsHumansInfectious Disease Transmission, VerticalMaleMass ScreeningPatient Acceptance of Health CarePregnancyPregnancy Complications, InfectiousRisk Reduction BehaviorSex WorkersSexual BehaviorSocial StigmaSocioeconomic FactorsWorld Health OrganizationConceptsAntiretroviral therapyVoluntary medical male circumcisionCombination prevention approachesOral antiretroviral drugsPre-exposure prophylaxisMedical male circumcisionSuccessful viral suppressionConsistent condom useEvidence-based modalitiesBoost vaccineViral suppressionHIV testingAntiretroviral coverageHIV transmissionAntiretroviral drugsBlood screeningVaginal microbicidesClean needlesInfection controlAdolescent sexual debutTransmission reductionFemale condomMale circumcisionSingle interventionHIV research
2011
Prevalence of syphilis among antenatal clinic attendees in Karachi: imperative to begin universal screening in Pakistan.
Shah SA, Kristensen S, Memon MA, Usman G, Ghazi A, John R, Sathiakumar N, Vermund SH. Prevalence of syphilis among antenatal clinic attendees in Karachi: imperative to begin universal screening in Pakistan. Journal Of The Pakistan Medical Association 2011, 61: 993-7. PMID: 22356034, PMCID: PMC3574871.Peer-Reviewed Original ResearchConceptsAntenatal clinic attendeesClinic attendeesRisk factorsMulti-center cross-sectional studySyphilis seroprevalence ratesLow-risk populationPrevalence of syphilisCross-sectional studyHigh prevalence ratesCases of syphilisMale drug useUniversal syphilisAntenatal clinicPartner notificationSyphilis serologySeroprevalence ratesPrevalence ratesSyphilis controlUniversal screeningBlood samplesRisk populationsDrug usersDrug useMultivariate analysisSyphilis
2010
A cluster-randomized trial of enhanced labor ward-based PMTCT services to increase nevirapine coverage in Lusaka, Zambia
Megazzini KM, Sinkala M, Vermund SH, Redden DT, Krebs DW, Acosta EP, Mwanza J, Goldenberg RL, Chintu N, Bulterys M, Stringer JS. A cluster-randomized trial of enhanced labor ward-based PMTCT services to increase nevirapine coverage in Lusaka, Zambia. AIDS 2010, 24: 447-455. PMID: 19926959, DOI: 10.1097/qad.0b013e328334b285.Peer-Reviewed Original ResearchConceptsWomen/infant pairsCluster-randomized trialNevirapine coverageInfant pairsLabour wardClinic coverageProbability of HIVProportion of HIVPrevention of motherStandard of carePMTCT programmePMTCT servicesChild transmissionHIV testingUnknown serostatusSurveillance periodIntervention periodControl clinicsRelative riskTreatment clinicsUmbilical cordHIVClinicGEE modelOdds of coverage
2009
Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol
Mwinga K, Vermund SH, Chen YQ, Mwatha A, Read JS, Urassa W, Carpenetti N, Valentine M, Goldenberg RL. Selected hematologic and biochemical measurements in African HIV-infected and uninfected pregnant women and their infants: the HIV Prevention Trials Network 024 protocol. BMC Pediatrics 2009, 9: 49. PMID: 19664210, PMCID: PMC2746190, DOI: 10.1186/1471-2431-9-49.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsBlood Cell CountDouble-Blind MethodFemaleFollow-Up StudiesGestational AgeHematocritHemoglobinsHIVHIV InfectionsHumansIncidenceInfantInfant, NewbornMalawiNevirapinePregnancyPregnancy Complications, InfectiousRetrospective StudiesRNA, ViralTanzaniaTreatment OutcomeYoung AdultZambiaConceptsHIV infectionPregnant African womenRandomized clinical trialsTime of laborComplete laboratory dataWeeks of ageNevirapine prophylaxisChild transmissionHIV exposureWeeks' gestationHIV statusPregnant womenNewborn infantsClinical trialsPublic clinicsHIVInfantsBiochemical measurementsCaucasian populationWomenLaboratory dataNormative dataAfrican womenInfectionWeeks
2008
Prevention of mother-to-child HIV transmission and management of paediatric HIV infection in Jamaica.
Vermund SH, Krogstad PA. Prevention of mother-to-child HIV transmission and management of paediatric HIV infection in Jamaica. West Indian Medical Journal 2008, 57: 187-8. PMID: 19583116.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeFemaleHIV InfectionsHumansInfant, NewbornInfectious Disease Transmission, VerticalJamaicaPediatricsPregnancyPregnancy Complications, InfectiousDo Targeted HIV Programs Improve Overall Care for Pregnant Women?
Potter D, Goldenberg RL, Chao A, Sinkala M, Degroot A, Stringer JS, Bulterys M, Vermund SH. Do Targeted HIV Programs Improve Overall Care for Pregnant Women? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2008, 47: 79-85. PMID: 17984757, PMCID: PMC2745056, DOI: 10.1097/qai.0b013e31815d2f71.Peer-Reviewed Original ResearchMeSH KeywordsChildFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalMaternal Health ServicesPregnancyPregnancy Complications, InfectiousPreventive Health ServicesSyphilisSyphilis SerodiagnosisZambiaConceptsPrevalence odds ratiosHIV programsPMTCT programme implementationChild HIV transmissionPrevention of motherConfidence intervalsRoutine clinical servicesDisease-specific researchHealth policy makersAntenatal clinicSyphilis treatmentHIV transmissionPregnant womenOverall careOdds ratioFirst visitCare impactClinical servicesService programsImplementation of researchScreeningProgram implementationClinicVisitsCare
2007
Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women
Banda Y, Chapman V, Goldenberg RL, H. B, Vermund SH, Stringer JS. Influence of body mass index on pregnancy outcomes among HIV‐infected and HIV‐uninfected Zambian women. Tropical Medicine And International Health 2007, 12: 856-861. PMID: 17596253, PMCID: PMC2570322, DOI: 10.1111/j.1365-3156.2007.01857.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultBirth WeightBody Mass IndexFemaleHIV InfectionsHumansInfant, NewbornInfectious Disease Transmission, VerticalParityPregnancyPregnancy Complications, InfectiousPregnancy OutcomeRisk FactorsStillbirthZambiaConceptsBody mass indexPregnancy outcomesBirth weightInfant weightMass indexZambian womenBMI unitsLower body mass indexChild transmission ratePerinatal HIV transmissionPrevention of motherHIV viral loadInfant birth weightMean birth weightTransmission of HIVNevirapine administrationPrior stillbirthBMI quartilesCD4 countChild transmissionViral loadHIV transmissionMaternal parityUnivariate analysisClinical trialsMonitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa
Reithinger R, Megazzini K, Durako SJ, Harris DR, Vermund SH. Monitoring and evaluation of programmes to prevent mother to child transmission of HIV in Africa. The BMJ 2007, 334: 1143. PMID: 17540943, PMCID: PMC1885318, DOI: 10.1136/bmj.39211.527488.94.Peer-Reviewed Original ResearchEarly clinical and immune response to NNRTI-based antiretroviral therapy among women with prior exposure to single-dose nevirapine
H BH, Sinkala M, Stringer EM, Cantrell RA, Mtonga V, Bulterys M, Zulu I, Kankasa C, Wilfert C, Weidle PJ, Vermund SH, Stringer J. Early clinical and immune response to NNRTI-based antiretroviral therapy among women with prior exposure to single-dose nevirapine. AIDS 2007, 21: 957-964. PMID: 17457089, PMCID: PMC2745970, DOI: 10.1097/qad.0b013e32810996b2.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveCD4 Lymphocyte CountDrug Administration ScheduleEpidemiologic MethodsFemaleHIV InfectionsHumansInfectious Disease Transmission, VerticalNevirapinePregnancyPregnancy Complications, InfectiousReverse Transcriptase InhibitorsTreatment FailureTreatment OutcomeConceptsSingle-dose nevirapineClinical treatment failureCD4 cell responseAntiretroviral therapyTreatment failureNVP exposureTreatment outcomesCell responsesShort-term treatment outcomesPrior exposureChild HIV transmissionPrevention of motherCD4 cell changesPoor treatment outcomesNon-nucleoside reverseSignificant differencesWorld Health Organization guidelinesHealth Organization guidelinesART initiationCohort evaluationMultivariable analysisHIV transmissionHIV treatmentRisk factorsImmune response