2023
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study
Pieri O, Bezerra F, Coelho P, Enk M, Favre T, Graeff-Teixeira C, Oliveira R, Reis M, Andrade L, Beck L, Favero V, Fialho T, Guimarães R, Oliveira B, Pascoal V, Pinheiro M, Santos R, Silva L, Siqueira I, Souza R, Katz N. Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study. Revista Da Sociedade Brasileira De Medicina Tropical 2023, 56: e0238-2022. PMID: 36700600, PMCID: PMC9870275, DOI: 10.1590/0037-8682-0238-2022.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, HelminthBrazilFecesHumansPoint-of-Care SystemsPrevalenceSchistosoma mansoniSchistosomiasis mansoniSensitivity and SpecificityConceptsCathodic antigenKato-KatzUrine-based pointSchistosomiasis mansoni infectionDifferent prevalence estimatesCare diagnostic testsSchistosomiasis elimination programmesWorld Health OrganizationMansoni infectionMulticenter studyStool samplesUrine pointPrevalence estimatesS. mansoniElimination programInfection statusDiagnostic testsHealth OrganizationUrine samplesHelmintexAntigenInfectionPrevalenceMansoniCare
2008
Schistosoma mansoni Triose Phosphate Isomerase Peptide MAP4 is Able to Trigger Naïve Donor Immune Response Towards a Type‐1 Cytokine Profile
Reis E, Carmo T, Athanazio R, Reis M, Harn D. Schistosoma mansoni Triose Phosphate Isomerase Peptide MAP4 is Able to Trigger Naïve Donor Immune Response Towards a Type‐1 Cytokine Profile. Scandinavian Journal Of Immunology 2008, 68: 169-176. PMID: 18565118, DOI: 10.1111/j.1365-3083.2008.02131.x.Peer-Reviewed Original ResearchConceptsPeripheral blood mononuclear cellsSchistosoma mansoni soluble egg antigenDendritic cellsCytokine productionAutologous peripheral blood mononuclear cellsType 1 cytokine profileMonocyte-derived dendritic cellsDonor dendritic cellsDonor immune responsesTh1-type responseT cell subsetsBlood mononuclear cellsIFN-gamma productionT cell epitopesMultiple antigen peptideMajor cell populationRecall stimulationCytokine profileIL-10Egg antigenMononuclear cellsT cellsImmune responseIFN-gammaMouse model
2007
Naïve Donor Responses to Schistosoma mansoni Soluble Egg Antigens
Reis E, Azevedo T, McBride A, Harn D, Reis M. Naïve Donor Responses to Schistosoma mansoni Soluble Egg Antigens. Scandinavian Journal Of Immunology 2007, 66: 662-670. PMID: 18021364, DOI: 10.1111/j.1365-3083.2007.02024.x.Peer-Reviewed Original ResearchConceptsSchistosoma mansoni soluble egg antigenNaïve human peripheral blood mononuclear cellsSoluble egg antigenIL-10Egg antigenIL-5T cellsT helper cell responsesHuman peripheral blood mononuclear cellsPeripheral blood mononuclear cellsDonor dendritic cellsTh2-type responseTh2-like responseBlood mononuclear cellsPronounced CD4Dendritic cellsIL-12p40Immune suppressionIL-6Mononuclear cellsCytokine secretionDonor responsesIFN-gammaCD4Day 7
1986
Stage and species specificity of antigens encoded by two geographic strains of Schistosoma mansoni mRNA.
Blanton R, Horowitz S, Reis M, Rottman F, Andrade Z, Mahmoud A. Stage and species specificity of antigens encoded by two geographic strains of Schistosoma mansoni mRNA. Journal Of Parasitology 1986, 72: 445-53. PMID: 3091803, DOI: 10.2307/3281685.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, HelminthBrazilCross ReactionsHumansMiceMice, Inbred C57BLMolecular WeightProtein BiosynthesisPuerto RicoRNA, MessengerSchistosoma haematobiumSchistosoma japonicumSchistosoma mansoniSchistosomiasis haematobiaSchistosomiasis japonicaSchistosomiasis mansoniSpecies SpecificityConceptsS. mansoniImmune human seraAntigen of MrGroup of antigensAdult worm mRNAAntigenic poolSchistosome infectionIntensity of infectionSchistosoma haematobiumIndividual seraAntigenAntigenic specificityAntigenic differencesSerumSchistosoma japonicumCross-reactive proteinEgg countsBrazilian parasitesInfectionMansoniMolecular weight proteinsHuman serumDifferent geographic strainsSpecies specificityHigh molecular weight proteins