Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer
Deloria AJ, Höflmayer D, Kienzl P, Łopatecka J, Sampl S, Klimpfinger M, Braunschmid T, Bastian F, Lu L, Marian B, Stättner S, Holzmann K. Epithelial splicing regulatory protein 1 and 2 paralogues correlate with splice signatures and favorable outcome in human colorectal cancer. Oncotarget 2016, 5: 73800-73816. PMID: 27650542, PMCID: PMC5342015, DOI: 10.18632/oncotarget.12070.Peer-Reviewed Original ResearchConceptsColorectal cancerEpithelial-mesenchymal transitionPrognostic valueNon-neoplastic colorectal epitheliumPrognosis of CRCFavorable overall survivalHuman colorectal cancerRole of ESRP1Overall survivalCRC casesPathological stageCRC cellsPrognostic stratificationFavorable outcomeTumor stagingClinical dataTCGA cohortColorectal epitheliumTumor progressionMicrosatellite instabilityMicrosatellite stabilityTumor cellsEarly detectionProtein 1Tissue expression