2013
Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population
Manini A, Jacobs M, Vlahov D, Hurd Y. Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population. Journal Of Medical Toxicology 2013, 9: 148-154. PMID: 23318993, PMCID: PMC3648633, DOI: 10.1007/s13181-012-0286-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlternative SplicingAmino Acid SubstitutionBenzodiazepinesCohort StudiesDrug OverdoseFemaleFollow-Up StudiesGenetic Association StudiesGenetic Predisposition to DiseaseHeart ArrestHumansMaleNarcoticsPilot ProjectsPolymorphism, Single NucleotideProspective StudiesReceptors, Opioid, muRespiratory InsufficiencySeverity of Illness IndexSympathomimeticsUnited StatesConceptsAcute drug overdoseG variant alleleClinical severityVariant allelesEmergency departmentDrug overdoseSingle nucleotide polymorphismsConsecutive adult ED patientsHuman mu-opioid receptor geneReceptor single nucleotide polymorphismsWorse clinical severityAdult ED patientsObservational cohort studyUrban teaching hospitalMu-opioid receptor geneAbove single nucleotide polymorphismsCohort studyED patientsRespiratory arrestCardiac arrestClinical variablesAcute drugSevere outcomesTeaching hospitalBlood samples
2007
Explaining Racial Disparities in Incidence of and Survival from Out-of-Hospital Cardiac Arrest
Galea S, Blaney S, Nandi A, Silverman R, Vlahov D, Foltin G, Kusick M, Tunik M, Richmond N. Explaining Racial Disparities in Incidence of and Survival from Out-of-Hospital Cardiac Arrest. American Journal Of Epidemiology 2007, 166: 534-543. PMID: 17584756, DOI: 10.1093/aje/kwm102.Peer-Reviewed Original ResearchConceptsAge-adjusted survivalInitial cardiac rhythmHospital cardiac arrestCardiac arrestCardiac rhythmAge-adjusted relative oddsEthnic disparitiesPrior functional statusProspective observational studyAge-adjusted incidenceEmergency medical services responseLikelihood of receiptFull multivariable modelOOHCA patientsHospital dischargeConsecutive casesFunctional statusCardiopulmonary resuscitationMultivariable modelObservational studyVentricular fibrillationLow prevalenceRelative oddsOOHCARacial disparities