2000
Screening for Hepatitis C Virus in Human Immunodeficiency Virus-Infected Individuals
Thio C, Nolt K, Astemborski J, Vlahov D, Nelson K, Thomas D. Screening for Hepatitis C Virus in Human Immunodeficiency Virus-Infected Individuals. Journal Of Clinical Microbiology 2000, 38: 575-577. PMID: 10655348, PMCID: PMC86151, DOI: 10.1128/jcm.38.2.575-577.2000.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHCV RNANegative participantsHepatitis C virus antibody testHuman immunodeficiency virus-infected individualsHepatitis C virus screeningThird-generation enzyme immunoassayHIV-negative participantsVirus-infected individualsHepatitis C virusInjection drug usersThird-generation assaysCOBAS AMPLICOR systemFalse-negative testsThird-generation testsFalse-negative resultsAcute infectionHIV infectionImmunodeficiency virusC virusAntibody formationAntibody testHCVVirus screeningAmplicor system
1999
Persistence of viremia and the importance of long‐term follow‐up after acute hepatitis C infection
Villano S, Vlahov D, Nelson K, Cohn S, Thomas D. Persistence of viremia and the importance of long‐term follow‐up after acute hepatitis C infection. Hepatology 1999, 29: 908-914. PMID: 10051497, DOI: 10.1002/hep.510290311.Peer-Reviewed Original ResearchConceptsRecombinant immunoblot assayHCV RNAAcute infectionViral clearanceAcute hepatitis C virus (HCV) infectionAcute hepatitis C infectionHepatitis C virus infectionPersistence of viremiaAcute HCV infectionAcute hepatitis CC virus infectionHepatitis C infectionTime of seroconversionPeak viral titersHealth care providersSingle laboratory testIllicit drug useHCV seroconversionC infectionHCV infectionHepatitis CPersistent viremiaClinical featuresHCV subtypesPolymerase chain reaction
1997
Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression
Smith M, Dean M, Carrington M, Winkler C, Huttley G, Lomb D, Goedert J, O'Brien T, Jacobson L, Kaslow R, Buchbinder S, Vittinghoff E, Vlahov D, Hoots K, Hilgartner M, Study H, San Francisco City Cohort ALIVE Study M, O'Brien S. Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression. Science 1997, 277: 959-965. PMID: 9252328, DOI: 10.1126/science.277.5328.959.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeBlack PeopleCohort StudiesDisease ProgressionGenotypeHaplotypesHeterozygoteHIV InfectionsHIV-1HumansMutationPolymerase Chain ReactionPolymorphism, Restriction Fragment LengthPolymorphism, Single-Stranded ConformationalProportional Hazards ModelsReceptors, CCR2Receptors, CCR5Receptors, ChemokineReceptors, CytokineReceptors, HIVSurvival AnalysisWhite PeopleConceptsHIV-1 infectionCCR2-64IDisease progressionHIV-1 disease progressionHIV-1-infected individualsLong-term survivorsCCR2-64I alleleReceptor geneChemokine receptor genesAIDS 2CCR2 chemokineSyndrome cohortAIDS patientsCCR5-Delta32Human immunodeficiencyChemokine receptorsCCR5 variantsCCR2CCR5InfectionIndependent effectsAfrican AmericansMutant genotypesProgressionGenetic association analysisComparison of PCR and hybrid capture methods for detection of human papillomavirus in injection drug-using women at high risk of human immunodeficiency virus infection
Shah K, Solomon L, Daniel R, Cohn S, Vlahov D. Comparison of PCR and hybrid capture methods for detection of human papillomavirus in injection drug-using women at high risk of human immunodeficiency virus infection. Journal Of Clinical Microbiology 1997, 35: 517-519. PMID: 9003632, PMCID: PMC229616, DOI: 10.1128/jcm.35.2.517-519.1997.Peer-Reviewed Original ResearchConceptsHuman papillomavirusHybrid captureInjection drug-using womenHuman immunodeficiency virus (HIV) infectionL1 consensus primersHIV-negative womenImmunodeficiency virus infectionPap smear abnormalitiesHuman immunodeficiency virusDrug-using womenHPV prevalencePositive womenSmear abnormalitiesImmunodeficiency virusViral loadHybrid capture methodVirus infectionHigh riskComparison of PCRLow specificityConsensus primersWomenPapillomavirusPCRInfection
1996
Detection of HIV-1 DNA in needle/syringes, paraphernalia, and washes from shooting galleries in Miami: a preliminary laboratory report.
Shah S, Shapshak P, Rivers J, Stewart R, Weatherby N, Xin K, Page J, Chitwood D, Mash D, Vlahov D, McCoy C. Detection of HIV-1 DNA in needle/syringes, paraphernalia, and washes from shooting galleries in Miami: a preliminary laboratory report. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1996, 11: 301-6. PMID: 8603266, DOI: 10.1097/00042560-199603010-00010.Peer-Reviewed Original ResearchConceptsNeedles/syringesHIV-1 DNAInjection drug usersHIV-1 proteinsHIV-1Polymerase chain reactionClean needlesHuman immunodeficiency virus type 1Immunodeficiency virus type 1Act of injectionVirus type 1Injection paraphernaliaPreliminary laboratory reportDrug usersShooting galleriesType 1Western blotReduction of riskEnvelope geneChain reactionGene DNAAntibodiesSyringesLaboratory reportsModification of behavior
1995
Correlates of Hepatitis C Virus Infections among Injection Drug Users
Thomas D, Vlahov D, Solomon L, Cohn S, Taylor E, Garfein R, Nelson K. Correlates of Hepatitis C Virus Infections among Injection Drug Users. Medicine 1995, 74: 212-220. PMID: 7623656, DOI: 10.1097/00005792-199507000-00005.Peer-Reviewed Original ResearchConceptsInjection drug usersHepatitis C virus infectionC virus infectionHuman immunodeficiency virusHCV infectionDrug usersVirus infectionMajority of HCVYears of injectingLong-term drug usersHCV RNASerologic evidenceImmunodeficiency virusBloodborne pathogensInjection drugsViral persistenceImmune responsePersistent infectionHigh riskHCVDrug useBiologic basisStudy participantsInfectionIllicit drugsHuman Immunodeficiency Virus Type 1 env and p17gag Sequence Variation in Polymerase Chain Reaction-Positive, Seronegative Injection Drug Users
Markham R, Yu X, Farzadegan H, Ray S, Vlahov D. Human Immunodeficiency Virus Type 1 env and p17gag Sequence Variation in Polymerase Chain Reaction-Positive, Seronegative Injection Drug Users. The Journal Of Infectious Diseases 1995, 171: 797-804. PMID: 7706805, DOI: 10.1093/infdis/171.4.797.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceBase SequenceCross-Sectional StudiesDNA, ViralFemaleGag Gene Products, Human Immunodeficiency VirusGene Products, envGene Products, gagGenes, envGenes, gagGenetic VariationHIV AntigensHIV InfectionsHIV-1HumansMaleMolecular Sequence DataPhylogenyPolymerase Chain ReactionSequence AlignmentSequence Analysis, DNASubstance Abuse, IntravenousViral ProteinsConceptsSeronegative injection drug usersInjection drug usersDrug usersHuman Immunodeficiency Virus Type 1 EnvCross-sectional studyPolymerase chainHIV-1 genesThird hypervariable regionAbility of virusesV3 loopMucosal surfacesIntersubject variationEnvelope regionInfected cellsAmino acid variationsEnvP17gagSeminal fluidVirusAcid variationsHypervariable regionInfectionDisease
1993
Detection of Human Immunodeficiency Virus Type 1 Infection by Polymerase Chain Reaction in a Cohort of Seronegative Intravenous Drug Users
Farzadegan H, Vlahov D, Solomon L, Muñoz A, Astemborski J, Taylor E, Burnley A, Nelson K. Detection of Human Immunodeficiency Virus Type 1 Infection by Polymerase Chain Reaction in a Cohort of Seronegative Intravenous Drug Users. The Journal Of Infectious Diseases 1993, 168: 327-331. PMID: 8335969, DOI: 10.1093/infdis/168.2.327.Peer-Reviewed Original ResearchConceptsSeronegative intravenous drug usersIntravenous drug usersHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionType 1 infectionPolymerase chain reactionDrug usersHIV-1 infectionHIV-1 antibodiesChain reactionLarge cohortBlood specimensProviral DNAInfectionCohortPCR analysisPersonsSerologyFollowVisitsAntibodiesMonths
1991
Diagnosis and differentiation of HTLV-I and HTLV-II infection by enzyme immunoassays using synthetic peptides.
Viscidi R, Hill P, Li S, Cerny E, Vlahov D, Farzadegan H, Halsey N, Kelen G, Quinn T. Diagnosis and differentiation of HTLV-I and HTLV-II infection by enzyme immunoassays using synthetic peptides. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1991, 4: 1190-8. PMID: 1941526.Peer-Reviewed Original ResearchConceptsEnzyme immunoassayHTLV-IIAntibody reactivityPeptide enzyme immunoassayHTLV-II infectionEpidemiology of HTLVDifferentiation of HTLVMicrotiter plate enzyme immunoassaysPattern of reactivitySeronegative controlsEmergency departmentEnv peptidesPositive seraViral infectionNeurological diseasesHTLVSynthetic peptidesInfectionDrug abuseMajor envelope proteinEnvEnvelope proteinPatientsSerumAntibodies