1997
Markers of response to zidovudine monotherapy among treated HIV seroconverters. Italian Seroconversion Study.
Rezza G, Galai N, Pezzotti P, Vlahov D, Graham N, Viale P, Angarano G. Markers of response to zidovudine monotherapy among treated HIV seroconverters. Italian Seroconversion Study. Antiviral Therapy 1997, 2: 167-74. PMID: 11322271.Peer-Reviewed Original ResearchConceptsCD4 cell countInitiation of treatmentZidovudine monotherapyP24 antigenaemiaCell countConstitutional symptomsHIV seroconvertersRisk groupsCopies/Human immunodeficiency virus seroconvertersPlasma RNA viral loadHIV RNA copiesCD4 cell declineRNA viral loadStart of therapyMarker of responseAntigen-positive individualsAdditional predictive informationIndicator of responseStandard survival methodsTerms of progressionAntiretroviral therapyViral loadAntigen levelsDisease progression
1996
Temporal Trends of Initial CD4 Cell Counts Following Human Immunodeficiency Virus Seroconversion in Italy, 1985–1992
Galai N, Lepri A, Vlahov D, Pezzotti P, Sinicco A, Rezza G, Study H. Temporal Trends of Initial CD4 Cell Counts Following Human Immunodeficiency Virus Seroconversion in Italy, 1985–1992. American Journal Of Epidemiology 1996, 143: 278-282. PMID: 8561162, DOI: 10.1093/oxfordjournals.aje.a008739.Peer-Reviewed Original ResearchConceptsCD4 cell measurementsInitial CD4 cell countHuman immunodeficiency virus (HIV) seroconversionCD4 cell countCell countCD4 cell count increaseItalian Seroconversion StudyLow CD4 countMonths of seroconversionYear of seroconversionCD4 cell levelsCell count increaseMedian lag timeCD4 countCD4 levelsHIV seroconversionPositive serologyNegative serologyHIV seroconvertersClinical centersRisk groupsSeroconversion StudySeroconversionMultivariate modelLag time
1995
Clinical characteristics and prognostic value of acute retroviral syndrome among injecting drug users
Dorrucci M, Rezza G, Vlahov D, Pezzotti P, Sinicco A, Nicolosi A, Lazzarin A, Galai N, Gafà S, Pristerà R. Clinical characteristics and prognostic value of acute retroviral syndrome among injecting drug users. AIDS 1995, 9: 597-604. PMID: 7662199, DOI: 10.1097/00002030-199506000-00011.Peer-Reviewed Original ResearchConceptsAcute retroviral syndromeHIV infectionHIV seroconvertersRelative hazardDrug usersFirst positive HIV testYear of seroconversionPositive HIV testRate of CD4Kaplan-Meier estimatesCumulative AIDS incidenceAsymptomatic seroconvertersHIV seroconversionClinical characteristicsHIV testClinical progressionPrognostic valueProspective studyClinical centersSeroconvertersCell declineSeroconversionCell countSyndromeNatural historyChanges in Markers of Disease Progression in HIV-1 Seroconverters
Galai N, Vlahov D, Margolick J, Chen K, Graham N, Munoz A. Changes in Markers of Disease Progression in HIV-1 Seroconverters. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1995, 8: 66-82. PMID: 8548349, DOI: 10.1097/00042560-199501000-00011.Peer-Reviewed Original ResearchConceptsHomosexual menDrug usersDisease progressionRisk groupsHuman immunodeficiency virus (HIV) disease progressionHIV-1 seroconversionHIV-1 seroconvertersT lymphocyte subsetsImmune deficiency syndromeWhite homosexual menCD8 percentagesTotal lymphocytesHIV infectionSimilar CD4HIV seroconvertersDeficiency syndromeInitial courseSeroconversionCD4Long incubation periodSeroconvertersMenCohortInfectionSimilar rates
1994
Field effectiveness of needle disinfection among injecting drug users.
Vlahov D, Astemborski J, Solomon L, Nelson K. Field effectiveness of needle disinfection among injecting drug users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1994, 7: 760-6. PMID: 8207660.Peer-Reviewed Original ResearchConceptsHIV seroconversionOdds ratioDrug usersNeedle disinfectionPutative protective effectCase-control studyCorresponding odds ratiosSterile injection equipmentDisinfectant useInjection equipmentLimited statistical powerStudy entryHIV seroconvertersResidual confoundingPossible confoundersCocaine injectionProtective effectSeroconversionDrug useUse of disinfectantsBlack heterosexualsPractice variablesField effectivenessSeroconvertersSeronegatives
1991
HIV SEROCONVERSION AND DISINFECTION OF INJECTION EQUIPMENT AMONG INTRAVENOUS DRUG USERS, BALTIMORE, MARYLAND
Vlahov D, Muntoz A, Celentano D, Cohn S, Anthony J, Chiicoat H, Nelson K. HIV SEROCONVERSION AND DISINFECTION OF INJECTION EQUIPMENT AMONG INTRAVENOUS DRUG USERS, BALTIMORE, MARYLAND. Epidemiology 1991, 2: 444-446. PMID: 1790197, DOI: 10.1097/00001648-199111000-00010.Peer-Reviewed Original ResearchConceptsIntravenous drug usersDrug usersHIV seroconversionProtective effectUse of disinfectantsPutative protective effectCase-control studyCorresponding odds ratiosOdds of seroconversionDisinfectant useLimited protective effectUse of cocaineStudy entryHIV seroconvertersOdds ratioSeroconversionInjection equipmentOddsSeroconvertersSeronegativesDisinfectants