2016
Change in attitudes and knowledge of problem drug use and harm reduction among a community cohort in Kabul, Afghanistan.
Todd C, Stanekzai M, Nasir A, Fiekert K, Orr M, Strathdee S, Vlahov D. Change in attitudes and knowledge of problem drug use and harm reduction among a community cohort in Kabul, Afghanistan. Eastern Mediterranean Health Journal 2016, 22: 183-92. PMID: 27334075, DOI: 10.26719/2016.22.3.183.Peer-Reviewed Original ResearchConceptsDrug usersHarm reductionProvision of condomsPre-post evaluationCommunity cohortDrug treatmentProblem drug useSyringe distributionFurther community educationDrug useInterview questionnaireConvenience sampleMedical professionalsAgreement levelCommunity educationCommunity representativesDrug policyCommunity supportPeriod of expansionAfghanistanProfessionalsCohortCondomsKabul
2005
Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study
Modi W, Scott K, Goedert J, Vlahov D, Buchbinder S, Detels R, Donfield S, O'Brien S, Winkler C. Haplotype analysis of the SDF-1 (CXCL12) gene in a longitudinal HIV-1/AIDS cohort study. Genes & Immunity 2005, 6: 691-698. PMID: 16177829, DOI: 10.1038/sj.gene.6364258.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAllelesBlack or African AmericanChemokine CXCL12Chemokines, CXCChildCohort StudiesDisease ProgressionFemaleGene FrequencyHaplotypesHIV InfectionsHIV-1HumansLongitudinal StudiesMaleOdds RatioPolymorphism, Single NucleotideRisk FactorsSurvival AnalysisUnited StatesWhite PeopleConceptsSDF-1 geneCohort studySingle nucleotide polymorphismsAfrican AmericansOnly natural ligandSingle disease outcomesX4 HIV-1HIV-1 infectionAIDS Cohort StudyRisk of infectionMACS cohortDisease outcomeHIV-1Epidemiological studiesSDF-1Significant associationChemokine genesInfectionRs1801157Natural ligandProgressionHaplotype analysisCommon haplotypeCXCR4CohortSexual Risk Behavior Among Injection Drug Users Before Widespread Availability of Highly Active Antiretroviral Therapy
Rusch M, Farzadegan H, Tarwater P, Safaeian M, Vlahov D, Strathdee S. Sexual Risk Behavior Among Injection Drug Users Before Widespread Availability of Highly Active Antiretroviral Therapy. AIDS And Behavior 2005, 9: 289-299. PMID: 16133905, DOI: 10.1007/s10461-005-9003-4.Peer-Reviewed Original ResearchConceptsInjection drug usersCondom useAntiretroviral therapyHIV testingDrug usersEligible injection drug usersRisk behaviorsActive antiretroviral therapyInconsistent condom useSexual risk behaviorsIDU cohortHIV transmissionRetrospective analysisLower riskStudy exposureSexual riskLong-term studiesTherapySignificant changesCounselingRiskExposureLogistic modelWidespread availabilityCohortSuicidal ideation among African-American non-injection drug users.
Havens J, Ompad D, Latkin C, Fuller C, Arria A, Vlahov D, Strathdee S. Suicidal ideation among African-American non-injection drug users. Ethnicity & Disease 2005, 15: 110-5. PMID: 15720057.Peer-Reviewed Original ResearchConceptsSuicidal ideationDrug usersDrug dependenceNon-injection drug usersCommunity-based cohortInterview-administered questionnaireMultiple logistic regressionDrug use historyUse of heroinAfrican American drug usersMedian agePsychiatric comorbidityDepressive symptomsMore drugsSuicidal thoughtsLogistic regressionIdeationAfrican AmericansUse historyParticipantsComorbiditiesCohortSymptomsYearsHeroin
2001
Racial Differences in HLA Class II Associations with Hepatitis C Virus Outcomes
Thio C, Thomas D, Goedert J, Vlahov D, Nelson K, Hilgartner M, O’Brien S, Karacki P, Marti D, Astemborski J, Carrington M. Racial Differences in HLA Class II Associations with Hepatitis C Virus Outcomes. The Journal Of Infectious Diseases 2001, 184: 16-21. PMID: 11398104, DOI: 10.1086/321005.Peer-Reviewed Original ResearchConceptsHuman leukocyte antigenClass II associationsViral clearanceClass II HLA typingClass II human leukocyte antigenHepatitis C virus clearanceHLA class II associationsCD4 T cell responsesT cell responsesClass II allelesHepatitis C virus outcomeHCV clearanceLeukocyte antigenVirus clearanceViral persistenceHLA typingImmune responseHomogeneous cohortCell responsesWhite subjectsDiverse cohortCohortClearanceVaried cohortsBlack subjectsImprovement of Anemia Among HIV-Infected Injection Drug Users Receiving Highly Active Antiretroviral Therapy
Semba R, Shah N, Vlahov D. Improvement of Anemia Among HIV-Infected Injection Drug Users Receiving Highly Active Antiretroviral Therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2001, 26: 315-319. DOI: 10.1097/00042560-200104010-00003.Peer-Reviewed Original Research
2000
Influence of CCR5 promoter haplotypes on AIDS progression in African–Americans
An P, Martin M, Nelson G, Carrington M, Smith M, Gong K, Vlahov D, O'Brien S, Winkler C. Influence of CCR5 promoter haplotypes on AIDS progression in African–Americans. AIDS 2000, 14: 2117-2122. PMID: 11061652, DOI: 10.1097/00002030-200009290-00007.Peer-Reviewed Original ResearchConceptsCCR5 promoter haplotypesAIDS progressionSurvival analysisAfrican AmericansNatural history cohort studyPromoter haplotypesRate of progressionPromoter variantsCohort studyCCR5 alleleRapid progressionCaucasian cohortProgressionCaucasiansComplete linkage disequilibriumCCR2AIDSUnidentified polymorphismsRacial groupsLinkage disequilibriumSeroconvertersCCR5CohortHaplotypes
1997
Nutritional status and its behavioral and clinical correlates in the hers cohort of HIV-infected and at-risk uninfected women
Smith D, Hanson D, Graham N, Flynn M, Greenberg B, Ding A, Vlahov D. Nutritional status and its behavioral and clinical correlates in the hers cohort of HIV-infected and at-risk uninfected women. Nutrition 1997, 13: 270. DOI: 10.1016/s0899-9007(97)82630-5.Peer-Reviewed Original Research
1996
RE: “DETERMINANTS OF HIV DISEASE PROGRESSION AMONG HOMOSEXUAL MEN REGISTERED IN THE TRICONTINENTAL SEROCONVERTER STUDY” AND “PROGRESSION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTION AMONG HOMOSEXUAL MEN IN HEPATITIS B VACCINE TRIAL COHORTS IN AMSTERDAM, NEW YORK CITY, AND SAN FRANCISCO, 1978–1991”
Zwahlen M, Vlahov D, Hoover D. RE: “DETERMINANTS OF HIV DISEASE PROGRESSION AMONG HOMOSEXUAL MEN REGISTERED IN THE TRICONTINENTAL SEROCONVERTER STUDY” AND “PROGRESSION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) INFECTION AMONG HOMOSEXUAL MEN IN HEPATITIS B VACCINE TRIAL COHORTS IN AMSTERDAM, NEW YORK CITY, AND SAN FRANCISCO, 1978–1991”. American Journal Of Epidemiology 1996, 143: 523-525. PMID: 8610669, DOI: 10.1093/oxfordjournals.aje.a008775.Peer-Reviewed Original Research
1995
Age, Gender, and Other Predictors of the Wasting Syndrome among HIV-1-Infected Injecting Drug Users
Sorkin J, Boiton P, Greenblatt J, Sithisarankul P, Vlahov D, Graham N. Age, Gender, and Other Predictors of the Wasting Syndrome among HIV-1-Infected Injecting Drug Users. Epidemiology 1995, 6: 172-177. PMID: 7742405, DOI: 10.1097/00001648-199503000-00015.Peer-Reviewed Original ResearchConceptsDrug usersDrug useFemale genderHuman immunodeficiency virus-1CD4 cell levelsCD4 T lymphocytesInjecting Drug UsersCase-control studyPresence of diarrheaImmunodeficiency virus-1Independent predictorsT lymphocytesSyndromeOlder ageWasting syndromeHIVWeight lossVirus 1AgeDiarrheaCrude predictorCohortPredictorsMore yearsLower percentageChanges in Markers of Disease Progression in HIV-1 Seroconverters
Galai N, Vlahov D, Margolick J, Chen K, Graham N, Munoz A. Changes in Markers of Disease Progression in HIV-1 Seroconverters. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1995, 8: 66-82. PMID: 8548349, DOI: 10.1097/00042560-199501000-00011.Peer-Reviewed Original ResearchConceptsHomosexual menDrug usersDisease progressionRisk groupsHuman immunodeficiency virus (HIV) disease progressionHIV-1 seroconversionHIV-1 seroconvertersT lymphocyte subsetsImmune deficiency syndromeWhite homosexual menCD8 percentagesTotal lymphocytesHIV infectionSimilar CD4HIV seroconvertersDeficiency syndromeInitial courseSeroconversionCD4Long incubation periodSeroconvertersMenCohortInfectionSimilar rates
1994
Maturity of human immunodeficiency virus infection and incubation period of acquired immunodeficiency syndrome in injecting drug users
Alcabes P, Muñoz A, Vlahov D, Friedland G. Maturity of human immunodeficiency virus infection and incubation period of acquired immunodeficiency syndrome in injecting drug users. Annals Of Epidemiology 1994, 4: 17-26. PMID: 7911376, DOI: 10.1016/1047-2797(94)90038-8.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeBaltimoreCD4-Positive T-LymphocytesCohort StudiesConfidence IntervalsHIV InfectionsHIV SeroprevalenceHomosexualityHumansIncidenceLeukocyte CountLife TablesMaleModels, StatisticalNew York CityPlatelet CountRegression AnalysisSubstance Abuse, IntravenousSurvival RateTime FactorsConceptsHIV infectionDrug usersImmunodeficiency syndromeMedian timeCombined cohortHomosexual menHuman immunodeficiency virus (HIV) infectionHuman immunodeficiency virus (HIV) epidemicPercent of CD4Immunodeficiency virus infectionIncident HIV infectionProduct-limit methodMarkers of maturityHIV incubation distributionsPlatelet countVirus infectionLarge cohortSeroconversionCohortInfectionConfidence intervalsIncubation distributionAIDSVirus epidemicPopulation groups
1993
Detection of Human Immunodeficiency Virus Type 1 Infection by Polymerase Chain Reaction in a Cohort of Seronegative Intravenous Drug Users
Farzadegan H, Vlahov D, Solomon L, Muñoz A, Astemborski J, Taylor E, Burnley A, Nelson K. Detection of Human Immunodeficiency Virus Type 1 Infection by Polymerase Chain Reaction in a Cohort of Seronegative Intravenous Drug Users. The Journal Of Infectious Diseases 1993, 168: 327-331. PMID: 8335969, DOI: 10.1093/infdis/168.2.327.Peer-Reviewed Original ResearchConceptsSeronegative intravenous drug usersIntravenous drug usersHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionType 1 infectionPolymerase chain reactionDrug usersHIV-1 infectionHIV-1 antibodiesChain reactionLarge cohortBlood specimensProviral DNAInfectionCohortPCR analysisPersonsSerologyFollowVisitsAntibodiesMonths
1992
T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection-Reply
Margolick J, Muñoz A, Vlahov D, Solomon L, Astemborski J, Cohn S, Nelson K. T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection-Reply. JAMA 1992, 268: 2517-2517. DOI: 10.1001/jama.1992.03490180047020.Peer-Reviewed Original Research
1991
HIV-1 infection and nervous system abnormalities among a cohort of intravenous drug users.
Royal W, Updike M, Seines O, Proctor T, Nance-Sproson L, Solomon L, Vlahov D, Cornblath D, McArthur J. HIV-1 infection and nervous system abnormalities among a cohort of intravenous drug users. Neurology 1991, 41: 1905-10. PMID: 1745346, DOI: 10.1212/wnl.41.12.1905.Peer-Reviewed Original ResearchConceptsHIV-1 serostatusIntravenous drug usersNeurologic abnormalitiesDrug usersSeronegative intravenous drug usersCD4 cell countHIV-seropositive subjectsHIV-1 infectionNervous system abnormalitiesConstitutional symptomsElectrophysiologic evaluationSeropositive participantsSeropositive subjectsElectrophysiologic abnormalitiesHIV infectionStudy cohortNeurologic diseaseSystem abnormalitiesHomosexual menCell countSerologic groupsCohortAbnormalitiesClear associationNeuropsychological testsThe Alive Study: A Longitudinal Study of HIV-1 Infection in Intravenous Drug Users: Description of Methods
Vlahov D, Anthony J, Muñoz A, Margolick J, Nelson K, Celentano D, Solomon L, Polk B. The Alive Study: A Longitudinal Study of HIV-1 Infection in Intravenous Drug Users: Description of Methods. Journal Of Drug Issues 1991, 21: 759-776. DOI: 10.1177/002204269102100406.Peer-Reviewed Original ResearchIntravenous drug usersHuman immunodeficiency virusDrug usersConfidential HIV testingHIV-1 infectionMonths of recruitmentALIVE studyHIV testingImmunodeficiency syndromeImmunodeficiency virusRisk factorsExtensive community outreachLongitudinal studyInfectionCommunity outreachBaltimore MarylandPercentSyndromeCohortRecruitmentProgressionMonths
1990
Blood and Plasma Donations Among a Cohort of Intravenous Drug Users
Nelson K, Vlahov D, Margolick J, Bernal M, Taylor E. Blood and Plasma Donations Among a Cohort of Intravenous Drug Users. JAMA 1990, 263: 2194-2197. PMID: 1969502, DOI: 10.1001/jama.1990.03440160056037.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHIV-1 seroprevalenceIntravenous drug useDrug usersHuman immunodeficiency virus serologic statusDrug useHIV test resultsCD4 lymphocytesEntire cohortPeripheral bloodSerologic statusDonor poolIntravenous drugsHIV-1Blood donationMost subjectsPlasma donationBloodCohortDonation historySeroprevalenceDonationLymphocytesHistoryPlasma