2023
Maternal medically diagnosed infection and antibiotic prescription during pregnancy and risk of childhood cancer: A population‐based cohort study in Taiwan, 2004 to 2015
Sirirungreung A, Lee P, Hu Y, Liew Z, Ritz B, Heck J. Maternal medically diagnosed infection and antibiotic prescription during pregnancy and risk of childhood cancer: A population‐based cohort study in Taiwan, 2004 to 2015. International Journal Of Cancer 2023, 154: 626-635. PMID: 37792464, PMCID: PMC10942658, DOI: 10.1002/ijc.34744.Peer-Reviewed Original ResearchConceptsPopulation-based cohort studyMaternal infectionAcute lymphoblastic leukemiaAntibiotic prescriptionsChildhood cancerCohort studyChildhood acute lymphoblastic leukemiaChild Health DatabaseRisk of hepatoblastomaProportional hazards modelMother-child pairsMedian followTaiwan MaternalCancer RegistryLymphoblastic leukemiaAntibiotic useNational HealthAntibiotic exposureElevated riskHigh riskHazards modelPregnancyChildhood leukemiaHealth databasesChildhood hepatoblastomaSeason of Conception and Risk of Cerebral Palsy
Zhuo H, Ritz B, Warren J, Liew Z. Season of Conception and Risk of Cerebral Palsy. JAMA Network Open 2023, 6: e2335164. PMID: 37738049, PMCID: PMC10517373, DOI: 10.1001/jamanetworkopen.2023.35164.Peer-Reviewed Original ResearchConceptsCerebral palsySeason of conceptionCalifornia birth recordsCohort studyPreterm birthRelative riskBirth recordsRisk of CPStatewide cohort studyEtiological risk factorsHigher Social Vulnerability IndexLength of gestationDiagnostic recordsNeighborhood-level factorsSummer conceptionsRisk factorsStratified analysisLive birthsMAIN OUTCOMEHigh riskCP riskPoisson regressionCP statusDevelopmental servicesNeuromotor disabilitiesExposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children
Vilhelmsson A, Rylander L, Jöud A, Lindh C, Mattsson K, Liew Z, Guo P, Ritz B, Källén K, Thacher J. Exposure to per- and polyfluoroalkyl substances in early pregnancy and risk of cerebral palsy in children. The Science Of The Total Environment 2023, 899: 165622. PMID: 37474063, DOI: 10.1016/j.scitotenv.2023.165622.Peer-Reviewed Original ResearchConceptsOdds ratioPreterm infantsEarly pregnancyPerfluorononanoic acidPrenatal PFAS exposureMaternal serum concentrationsCerebral palsy casesConfidence intervalsCase-control studyRisk of CPEnvironmental risk factorsPositive associationContinuous variablesHigh PFASPalsy casesBirth RegistryPreterm controlsCerebral palsyLifestyle factorsPreterm casesUnexplained etiologyPrenatal exposureSerum concentrationsRisk factorsPerfluorooctane sulfonateResidential proximity to unconventional oil and gas development and birth defects in Ohio
Gaughan C, Sorrentino K, Liew Z, Johnson N, Clark C, Soriano M, Plano J, Plata D, Saiers J, Deziel N. Residential proximity to unconventional oil and gas development and birth defects in Ohio. Environmental Research 2023, 229: 115937. PMID: 37076028, PMCID: PMC10198955, DOI: 10.1016/j.envres.2023.115937.Peer-Reviewed Original ResearchConceptsNeural tube defectsCertain birth defectsBirth defectsOdds ratioRegistry-based cohort studyTube defectsConfidence intervalsResidential proximityState birth recordsBirth defect typeState surveillance systemsMaternal residential proximityLimb reduction defectsCohort studyUnexposed mothersStructural birth defectsLive birthsInfant sexBirth recordsSpina bifidaReduction defectsFemale offspringDevelopmental toxicantsExposure metrics
2022
Parental Age and Childhood Risk for Cerebral Palsy in California
Zhou L, Meng Q, von Ehrenstein O, Xiao J, Gao Y, Wu Y, Ritz B, Liew Z. Parental Age and Childhood Risk for Cerebral Palsy in California. The Journal Of Pediatrics 2022, 255: 147-153.e6. PMID: 36372095, PMCID: PMC10121738, DOI: 10.1016/j.jpeds.2022.10.039.Peer-Reviewed Original ResearchConceptsCerebral palsyPaternal ageGreater riskPreterm birthMaternal ageParental ageRisk of CPYoung maternal ageBirth certificate recordsCase-control studyTime of deliveryChildren of mothersOlder paternal ageCP diagnosisPreterm deliveryOffspring riskCertificate recordsCP casesCP riskSingleton controlsAge 20Older mothersAge 25Older ageChildhood risk
2019
Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses’ Health Study II
Liew Z, Kioumourtzoglou MA, Roberts AL, O’Reilly É, Ascherio A, Weisskopf MG. Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses’ Health Study II. American Journal Of Epidemiology 2019, 188: 768-775. PMID: 30923825, PMCID: PMC6438812, DOI: 10.1093/aje/kwy288.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderHealth Study II cohortMaternal acetaminophen useHealth Study IIAcetaminophen useAcetaminophen exposureNurses' Health Study II cohortNurses' Health Study IIPrenatal acetaminophen exposureHyperactivity disorderChildhood attention-deficit/hyperactivity disorderTime of pregnancyExposure periodBiennial questionnairesMaternal useObservational studyDrug safetyStudy IIPrior reportsExposure approachPregnancyAcetaminophenCohortChildrenAssociation
2016
Prenatal maternal bereavement and mortality in the first decades of life: a nationwide cohort study from Denmark and Sweden
Yu Y, Cnattingius S, Olsen J, Parner E, Vestergaard M, Liew Z, Zhao N, Li J. Prenatal maternal bereavement and mortality in the first decades of life: a nationwide cohort study from Denmark and Sweden. Psychological Medicine 2016, 47: 389-400. PMID: 27762181, DOI: 10.1017/s003329171600266x.Peer-Reviewed Original ResearchConceptsPrenatal maternal bereavementMaternal bereavementMortality riskCohort studyIncreased long-term mortality riskPopulation-based cohort studyLong-term mortality riskNationwide cohort studyLong-term mortalityCause mortality riskExcess mortality riskChildren of mothersFetal programming hypothesisYears of ageYears of lifeEndocrine/Stressful life eventsFetal deathSingleton birthsMedical conditionsProgramming hypothesisHigh riskUnnatural causesCongenital malformationsPrenatal stress
2015
Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study
Liew Z, Ritz B, Virk J, Olsen J. Maternal use of acetaminophen during pregnancy and risk of autism spectrum disorders in childhood: A Danish national birth cohort study. Autism Research 2015, 9: 951-958. PMID: 26688372, DOI: 10.1002/aur.1591.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAttention Deficit Disorder with HyperactivityAutism Spectrum DisorderChildChild, PreschoolCohort StudiesComorbidityDenmarkFemaleHumansInfantInfant, NewbornMalePregnancyPrenatal Exposure Delayed EffectsProportional Hazards ModelsProspective StudiesRiskStatistics as TopicConceptsRisk of ASDHyperkinetic symptomsAcetaminophen useHazard ratioDanish National Birth CohortCox proportional hazards modelHyperactive behavioral phenotypesAutism spectrum disorderEnd of followNational Birth CohortComputer-assisted telephone interviewsProportional hazards modelInfantile autismConfident intervalFever medicationPsychiatric RegistryPrenatal useProspective dataMaternal useHyperkinetic disorderAcetaminophen exposureFetal lifeHazards modelDiagnosis of ASDBirth cohort
2014
Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort
Liew Z, Ritz B, von Ehrenstein OS, Bech BH, Nohr EA, Fei C, Bossi R, Henriksen TB, Bonefeld-Jørgensen EC, Olsen J. Attention Deficit/Hyperactivity Disorder and Childhood Autism in Association with Prenatal Exposure to Perfluoroalkyl Substances: A Nested Case–Control Study in the Danish National Birth Cohort. Environmental Health Perspectives 2014, 123: 367-373. PMID: 25616253, PMCID: PMC4383573, DOI: 10.1289/ehp.1408412.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderDanish National Birth CohortNational Birth CohortDeficit/hyperactivity disorderPrenatal exposureRisk ratioChildhood autismBirth cohortDanish National Hospital RegistryDanish Psychiatric Central RegistryNested Case-Control StudyRisk of ADHDNational Hospital RegistryPrenatal PFAS exposureHyperactivity disorderCase-control studyMother-child pairsPerfluoroalkyl substancesConsistent evidenceHospital registryProspective studyPlasma levelsNeurobehavioral problemsPFAS exposureCentral RegistryAcetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders
Liew Z, Ritz B, Rebordosa C, Lee PC, Olsen J. Acetaminophen Use During Pregnancy, Behavioral Problems, and Hyperkinetic Disorders. JAMA Pediatrics 2014, 168: 313-320. PMID: 24566677, DOI: 10.1001/jamapediatrics.2013.4914.Peer-Reviewed Original ResearchMeSH KeywordsAcetaminophenAdultAttention Deficit Disorder with HyperactivityChildChild, PreschoolDenmarkFemaleHumansHyperkinesisInfantMaleMental DisordersMothersPregnancyPrenatal Exposure Delayed EffectsProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsSurveys and QuestionnairesConceptsAcetaminophen useHyperkinetic disorderADHD-like behaviorsMental health problemsPrenatal exposureADHD medicationHigh riskDanish National Hospital RegistryDanish Psychiatric Central RegistryDanish National Birth CohortBehavioral problemsMothers' mental health problemsDanish Prescription RegistryMaternal acetaminophen useNational Hospital RegistryNational Birth CohortExposure-response trendsComputer-assisted telephone interviewsFetal brain developmentAge 7 yearsChildren 7 yearsAttention-deficit/hyperactivity disorderPublic health relevanceADHD prescriptionsMaternal inflammation