2023
Data integration and inference of gene regulation using single-cell temporal multimodal data with scTIE
Lin Y, Wu T, Chen X, Wan S, Chao B, Xin J, Yang J, Wong W, Wang Y. Data integration and inference of gene regulation using single-cell temporal multimodal data with scTIE. Genome Research 2023, 34: gr.277960.123. PMID: 38190633, PMCID: PMC10903952, DOI: 10.1101/gr.277960.123.Peer-Reviewed Original Research
2022
scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning
Lin Y, Wu T, Wan S, Yang J, Wong W, Wang Y. scJoint integrates atlas-scale single-cell RNA-seq and ATAC-seq data with transfer learning. Nature Biotechnology 2022, 40: 703-710. PMID: 35058621, PMCID: PMC9186323, DOI: 10.1038/s41587-021-01161-6.Peer-Reviewed Original ResearchConceptsData modalitiesTransfer learning methodDifferent data modalitiesSingle-cell multiomics dataTransfer learningUnlabeled dataMultimodal datasetLeverage informationNeural networkLearning methodsData compositionLabel transferLabel accuracyJoint visualizationHeterogeneous collectionPromising resultsUnprecedented paceVisualizationFrameworkMultiomics dataScRNA-seq dataDatasetNetworkScATAC-seq dataCell atlases