Longitudinal Effect of Hydroxyurea Therapy on Left Ventricular Diastolic Function in Sickle Cell Anemia
Rai P, Kang G, Naik R, Goldberg J, Zhao X, Ataga K, Joshi V, Hankins J. Longitudinal Effect of Hydroxyurea Therapy on Left Ventricular Diastolic Function in Sickle Cell Anemia. Blood 2019, 134: 1006. DOI: 10.1182/blood-2019-130905.Peer-Reviewed Original ResearchAbsolute reticulocyte countSickle cell anemiaEarly diastolic mitral annular velocityDiastolic mitral annular velocityLeft ventricular diastolic functionSt. Jude Children's Research HospitalVentricular diastolic dysfunctionDiastolic functionMitral annular velocityVentricular diastolic functionVentricular diastolic indicesDiastolic dysfunctionHU therapyFurther clinical developmentResearch HospitalDiastolic indicesEarly mortalityAnnular velocityLactic dehydrogenaseClinical developmentCell anemiaHematological parametersEarly mitral inflow velocityElevated pulmonary artery pressureLeft ventricular diastolic indicesNeurocognitive Impairment Predicts Poor Transition Outcomes Among Patients with Sickle Cell Disease
Saulsberry A, Partanen M, Porter J, Podila P, Hodges J, King A, Wang W, Zhao X, Kang G, Jacola L, Hankins J. Neurocognitive Impairment Predicts Poor Transition Outcomes Among Patients with Sickle Cell Disease. Blood 2019, 134: 519. DOI: 10.1182/blood-2019-121617.Peer-Reviewed Original ResearchSickle cell diseaseEconomic Hardship IndexSt. Jude Children's Research HospitalLast paediatric visitAdult careFurther clinical developmentResearch HospitalCare retentionAmbulatory servicesPediatric visitsCell diseaseClinical developmentExact testFirst adult visitSickle Cell ResearchPatients' cognitive levelAdult-centered careFisher's exact testLong latency periodWilcoxon rank sum testChi-square testNeurocognitive screening batteryGene therapyRank sum testAgios PharmaceuticalsEvaluation of Factors Influencing Health Literacy in Adolescents and Adults with Sickle Cell Disease
Bhatt N, Calhoun C, Hodges J, Nwosu C, Kang G, King A, Zhao X, Hankins J. Evaluation of Factors Influencing Health Literacy in Adolescents and Adults with Sickle Cell Disease. Blood 2019, 134: 2110. DOI: 10.1182/blood-2019-130755.Peer-Reviewed Original ResearchSt. Jude Children's Research HospitalLimited health literacySickle cell diseaseHealth literacy levelsNewest Vital SignAdequate health literacyResearch HospitalFurther clinical developmentHealth literacyNVS scoresCell diseaseSevere genotypeClinical developmentHealth outcomesSt. Louis Children's HospitalLow health literacy levelsYoung adultsDisease-modifying therapiesHealth literacy assessmentHealth literacy scoresLow health literacyCross-sectional studyAppropriate health decisionsCare of adolescentsAdults ages 15