Featured Publications
The Sordariomycetes: an expanding resource with Big Data for mining in evolutionary genomics and transcriptomics
Wang Z, Kim W, Wang Y, Yakubovich E, Dong C, Trail F, Townsend J, Yarden O. The Sordariomycetes: an expanding resource with Big Data for mining in evolutionary genomics and transcriptomics. Frontiers In Fungal Biology 2023, 4: 1214537. PMID: 37746130, PMCID: PMC10512317, DOI: 10.3389/ffunb.2023.1214537.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEvolutionary genomicsOmics dataFungal sexual developmentAncestral state analysisRichness of speciesDifferent taxonomic levelsAspects of biologySpecies/generaSystems biological analysisRegulatory network modelKnowledge of evolutionAscomycete genomesSordariomycetes classFungal evolutionTrait diversityDivergent lineagesFungal kingdomFungal biologyGenomic scaleSecondary metabolismModel genomesModel fungusModel speciesEcological diversityKey genetic elements
2023
Origins of lineage‐specific elements via gene duplication, relocation, and regional rearrangement in Neurospora crassa
Wang Z, Wang Y, Kasuga T, Hassler H, Lopez‐Giraldez F, Dong C, Yarden O, Townsend J. Origins of lineage‐specific elements via gene duplication, relocation, and regional rearrangement in Neurospora crassa. Molecular Ecology 2023 PMID: 37843462, DOI: 10.1111/mec.17168.Peer-Reviewed Original ResearchLineage-specific genesGene duplicationNew genesLineage-specific elementsWeighted gene correlation network analysisRecent gene duplicationNon-coding DNACell wall integrityCo-regulatory modulesGene correlation network analysisNon-coding sequencesCorrelation network analysisAntifungal toxinsGene syntenyNeurospora speciesGenus NeurosporaEvolutionary biologistsSuch cladesRegulatory machinerySequence repeatsModel speciesAncestral statusNeurospora crassaTranscriptomic dataDiverse functions
2018
Using evolutionary genomics, transcriptomics, and systems biology to reveal gene networks underlying fungal development
Wang Z, Gudibanda A, Ugwuowo U, Trail F, Townsend J. Using evolutionary genomics, transcriptomics, and systems biology to reveal gene networks underlying fungal development. Fungal Biology Reviews 2018, 32: 249-264. DOI: 10.1016/j.fbr.2018.02.001.ChaptersModel speciesFungal developmentGenome-wide gene expression dataEvolutionary developmental biologyEvo-devo researchGenome-wide analysisSystems biology strategiesGene expression dataEvolutionary genomicsSpecies phylogenyGenetic screenDevelopmental biologyDevelopmental traitsGene networksRegulatory networksFungal modelCell biologyModern biologyFossil recordKnockout strategiesDevelopmental processesMultiple speciesSystems biologyMolecular geneticsExpression data