Featured Publications
Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis
Ahmadzai N, Cheng W, Kilty S, Esmaeilisaraji L, Wolfe D, Bonaparte J, Schramm D, Fitzpatrick E, Lin V, Skidmore B, Hutton B. Pharmacologic and surgical therapies for patients with Meniere’s disease: A systematic review and network meta-analysis. PLOS ONE 2020, 15: e0237523. PMID: 32870918, PMCID: PMC7462264, DOI: 10.1371/journal.pone.0237523.Peer-Reviewed Original ResearchConceptsComplete vertigo controlEndolymphatic sac decompressionRandomized clinical trialsEndolymphatic duct blockageIT steroidsVertigo controlMeniere's diseaseIT gentamicinSurgical interventionSystematic reviewKey patient outcomesHigh cumulative dosageBest treatment optionSensorineural hearing lossEDB groupESD groupAural fullnessIntratympanic gentamicinSteroid injectionVertigo attacksHead trialsHearing preservationSurgical therapyCochrane LibraryCumulative dosage
2021
VTE Prophylaxis in Critically Ill Adults A Systematic Review and Network Meta-analysis
Fernando SM, Tran A, Cheng W, Sadeghirad B, Arabi YM, Cook DJ, Møller MH, Mehta S, Fowler RA, Burns KEA, Wells PS, Carrier M, Crowther MA, Scales DC, English SW, Kyeremanteng K, Kanji S, Kho ME, Rochwerg B. VTE Prophylaxis in Critically Ill Adults A Systematic Review and Network Meta-analysis. CHEST Journal 2021, 161: 418-428. PMID: 34419428, DOI: 10.1016/j.chest.2021.08.050.Peer-Reviewed Original ResearchConceptsIncidence of DVTRandomized clinical trialsMechanical compressive deviceRisk of DVTIll adultsCombination therapyRCTs of patientsSystematic reviewAdults A Systematic ReviewCombination pharmacologic therapyCompressive devicePrimary pharmacologic agentsRisk of VTELow-certainty evidencePrevention of VTEA Systematic ReviewNetwork Meta-AnalysisFull-text reviewThromboprophylaxis agentsVenous thromboprophylaxisVTE prophylaxisRecommendations AssessmentPharmacologic therapyPulmonary embolismIll patients