Featured Publications
Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses.
Hutton B, Hersi M, Cheng W, Pratt M, Barbeau P, Mazzarello S, Ahmadzai N, Skidmore B, Morgan SC, Bordeleau L, Ginex PK, Sadeghirad B, Morgan RL, Cole KM, Clemons M. Comparing Interventions for Management of Hot Flashes in Patients With Breast and Prostate Cancer: A Systematic Review With Meta-Analyses. Oncology Nursing Forum 2020, 47: e86-e106. PMID: 32555553, PMCID: PMC7891229, DOI: 10.1188/20.onf.e86-e106.Peer-Reviewed Original ResearchConceptsHot flash frequencyHot flashesProstate cancerHot flash scoreHistory of breastHot flash severityQuality of lifeFlash frequencyActive therapyPatients' qualitySystematic reviewAbstractTextMeta-AnalysisNarrative synthesisMore interventionsDATA EVALUATIONLiterature searchPatientsTherapyCancerBreastLittle dataInterventionMinimal dataTreatmentAccuracy of the Multinational Association of Supportive Care in Cancer (MASCC) and Clinical Index of Stable Febrile Neutropenia (CISNE) scores for predicting serious complications in adult patients with febrile neutropenia: A systematic review and meta-analysis
Zheng B, Toarta C, Cheng W, Taljaard M, Reaume N, Perry JJ. Accuracy of the Multinational Association of Supportive Care in Cancer (MASCC) and Clinical Index of Stable Febrile Neutropenia (CISNE) scores for predicting serious complications in adult patients with febrile neutropenia: A systematic review and meta-analysis. Critical Reviews In Oncology/Hematology 2020, 149: 102922. PMID: 32244162, DOI: 10.1016/j.critrevonc.2020.102922.Peer-Reviewed Original ResearchConceptsMultinational AssociationSupportive careSerious complicationsClinical indicesPooled sensitivitySystematic reviewFebrile neutropenia patientsCISNE scoreMASCC scoreFebrile neutropeniaAcute settingAdult patientsCochrane DatabaseNeutropenia patientsPatientsComplicationsScoresCancerCareAssociationSpecificityNeutropeniaMASCCEMBASEReviewNumber needed to treat in indirect treatment comparison
Guyot P, Cheng W, Tremblay G, Copher R, Burnett H, Li X, Makin C. Number needed to treat in indirect treatment comparison. Journal Of Comparative Effectiveness Research 2018, 7: 259-269. PMID: 29537878, DOI: 10.2217/cer-2017-0023.Peer-Reviewed Original ResearchConceptsRR-DTC patientsIndirect treatment comparisonIndirect comparisonRadioiodine-refractory differentiated thyroid cancer patientsDifferentiated thyroid cancer patientsTreatment comparisonsThyroid cancer patientsCancer patientsDichotomous outcomesLenvatinibPatientsSorafenibTreatment effectsNNTSummary measures
2024
Atezolizumab and bevacizumab in combination with TACE for patients with BCLC B HCC.
Stein S, Cheng W, Wiess C, Pollak J, Perez Lozada J, Chapiro J, Madoff D. Atezolizumab and bevacizumab in combination with TACE for patients with BCLC B HCC. Journal Of Clinical Oncology 2024, 42: tps584-tps584. DOI: 10.1200/jco.2024.42.3_suppl.tps584.Peer-Reviewed Original ResearchRates of grade 3Grade 3Child-Pugh A cirrhosisBCLC-B HCCCombination of atezolizumabCurative intent therapyMain portal veinRisk of bleedingDiagnosis of HCCSignificant autoimmune diseaseSingle arm pilot studyB HCCECOG PSEffective regimenOpen-labelOverall survivalGastroesophageal varicesIntent therapyPredicted probabilityAutoimmune diseasesHepatic arteryPortal veinHepatic encephalopathyPatientsImprove outcomes
2022
Performance of single serum progesterone in the evaluation of symptomatic first-trimester pregnant patients: a systematic review and meta-analysis
Ghaedi B, Cheng W, Ameri S, Abdulkarim K, Costain N, Zia A, Thiruganasambandamoorthy V. Performance of single serum progesterone in the evaluation of symptomatic first-trimester pregnant patients: a systematic review and meta-analysis. Canadian Journal Of Emergency Medicine 2022, 24: 611-621. PMID: 35921048, DOI: 10.1007/s43678-022-00332-x.Peer-Reviewed Original ResearchConceptsNon-viable pregnancyPregnancy viabilityViable pregnancyDiagnostic odds ratioProgesterone levelsFirst trimester pregnant patientsSingle serum progesterone levelSingle serum progesteroneUseful prognostic informationSerum progesterone levelsValue of progesteroneSensitivity 91.3Pregnant patientsSymptomatic patientsCochrane DatabaseFirst trimesterSerum progesteronePrognostic informationOdds ratioPrevalence ratesPatientsPregnancySummary estimatesSpecificity 75Predictive value
2021
Thromboembolic events following cardioversion of acute atrial fibrillation and flutter: a systematic review and meta-analysis
Wong BM, Perry JJ, Cheng W, Zheng B, Guo K, Taljaard M, Skanes AC, Stiell IG. Thromboembolic events following cardioversion of acute atrial fibrillation and flutter: a systematic review and meta-analysis. Canadian Journal Of Emergency Medicine 2021, 23: 500-511. PMID: 33715143, DOI: 10.1007/s43678-021-00103-0.Peer-Reviewed Original ResearchConceptsOral anticoagulation useAcute atrial fibrillationAnticoagulation useThromboembolic eventsAtrial fibrillationThromboembolic riskFlutter patientsInsufficient evidencePrimary analysisSecondary analysisDerSimonian-Laird random-effects modelSafety of cardioversionPrognostic Studies toolRisk of biasRandom-effects modelBackgroundRecent studiesInclusion criteriaMAIN OUTCOMELower riskFibrillationSystematic reviewEvent ratesCardioversionMore studiesPatients
2019
A systematic review and meta-analysis evaluating geriatric consultation on older trauma patients.
Eagles D, Godwin B, Cheng W, Moors J, Figueira S, Khoury L, Fournier K, Lampron J. A systematic review and meta-analysis evaluating geriatric consultation on older trauma patients. Journal Of Trauma And Acute Care Surgery 2019, 88: 446-453. PMID: 31876691, DOI: 10.1097/ta.0000000000002571.Peer-Reviewed Original ResearchConceptsOlder trauma patientsGeriatric consultationHospital lengthOlder patientsTrauma centerSystematic reviewDelirium incidenceDischarge destinationTrauma patientsTrauma careStandard trauma carePatients 65 yearsNewcastle-Ottawa ScaleMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsFull-text reviewHospital mortalityFirst systematic reviewCohort studyGeriatric assessmentGeriatric traumaIndependent reviewersInsufficient evidenceUnique citationsPatients