Featured Publications
Adverse Events Among Emergency Department Patients With Cardiovascular Conditions: A Multicenter Study
Calder LA, Perry J, Yan JW, De Gorter R, Sivilotti MLA, Eagles D, Myslik F, Borgundvaag B, Émond M, McRae AD, Taljaard M, Thiruganasambandamoorthy V, Cheng W, Forster AJ, Stiell IG. Adverse Events Among Emergency Department Patients With Cardiovascular Conditions: A Multicenter Study. Annals Of Emergency Medicine 2021, 77: 561-574. PMID: 33612283, DOI: 10.1016/j.annemergmed.2020.12.012.Peer-Reviewed Original ResearchConceptsAcute heart failureAdverse eventsEmergency department patientsED visitsDepartment patientsHeart failureAtrial fibrillationHealth care provider visitsRecent-onset atrial fibrillationClinical practice guideline adherenceIndex ED visitPractice guideline adherenceAdverse event incidenceProspective cohort studyAdverse event ratesCase summariesQuality improvement opportunitiesFactor themesAdverse event typesCanadian EDsSentinel diagnosesED dischargeProvider visitsAdult patientsCohort studyDoes N-Terminal Pro-B-Type Natriuretic Peptide Improve the Risk Stratification of Emergency Department Patients With Syncope?
Thiruganasambandamoorthy V, McRae AD, Rowe BH, Sivilotti MLA, Mukarram M, Nemnom MJ, Booth RA, Calder LA, Stiell IG, Wells GA, Cheng W, Taljaard M. Does N-Terminal Pro-B-Type Natriuretic Peptide Improve the Risk Stratification of Emergency Department Patients With Syncope? Annals Of Internal Medicine 2020, 172: 648-655. PMID: 32340039, DOI: 10.7326/m19-3515.Peer-Reviewed Original ResearchConceptsCanadian Syncope Risk ScoreSerious adverse eventsPro-B-type natriuretic peptideSerum NT-proBNP concentrationNT-proBNP concentrationsNT-proBNPNatriuretic peptideED patientsN-terminal pro-B-type natriuretic peptideTerminal pro-B-type natriuretic peptidePhysicians Services Incorporated FoundationIndex ED visitNT-proBNP valuesAdult ED patientsProspective cohort studySerum NT-proBNPEmergency department patientsNet reclassification indexHeterogeneity of outcomesAdjudication of outcomesNoncardiac eventsED dispositionAdverse eventsCohort studyComposite outcomeCohort Study of Features Used by Experts to Diagnose Transient Ischemic Attack
Fitzpatrick T, Gocan S, Wang CQ, Bourgoin A, Taljaard M, Cheng W, Dowlatshahi D, Stotts G, Shamy M. Cohort Study of Features Used by Experts to Diagnose Transient Ischemic Attack. The Neurohospitalist 2020, 10: 245-249. PMID: 32983341, PMCID: PMC7495706, DOI: 10.1177/1941874420908485.Peer-Reviewed Original ResearchTransient ischemic attackTIA/strokeStroke prevention clinicFinal diagnosisIschemic attackSecondary stroke prevention therapyStroke prevention servicesStroke prevention therapyMonocular vision lossRetrospective chart reviewLogistic regression analysisMultinomial logistic regression analysisBackward eliminationPrevention clinicStroke neurologistsChart reviewCohort studyNeurological eventsPrevention therapyUnilateral weaknessHomonymous hemianopiaReferral characteristicsVision lossSudden onsetInclusion criteriaPre-arrest and intra-arrest prognostic factors associated with survival after in-hospital cardiac arrest: systematic review and meta-analysis
Fernando SM, Tran A, Cheng W, Rochwerg B, Taljaard M, Vaillancourt C, Rowan KM, Harrison DA, Nolan JP, Kyeremanteng K, McIsaac DI, Guyatt GH, Perry JJ. Pre-arrest and intra-arrest prognostic factors associated with survival after in-hospital cardiac arrest: systematic review and meta-analysis. The BMJ 2019, 367: l6373. PMID: 31801749, PMCID: PMC6891802, DOI: 10.1136/bmj.l6373.Peer-Reviewed Original ResearchConceptsHospital cardiac arrestCardiac arrestPrognostic factorsSystematic reviewReduced oddsPrimary analysisInitial shockable rhythmIntra-arrest factorsPre-arrest factorsHigh-certainty evidenceChronic kidney diseaseDuration of resuscitationRisk of biasEnglish-language studiesWeb of ScienceActive malignancyCertainty evidenceCohort studyGRADE approachOdds of survivalCochrane DatabaseMale sexKidney diseaseShockable rhythmRelevant confounders
2023
Impact of Prophylactic Antibacterials on Coagulation Profiles and Bleeding in Patients with Acute Myeloid Leukemia/Myelodysplastic Syndrome
Allen C, Gautam S, Cheng W, Pine A, Podoltsev N, Zeidan A, Lee A, Shallis R. Impact of Prophylactic Antibacterials on Coagulation Profiles and Bleeding in Patients with Acute Myeloid Leukemia/Myelodysplastic Syndrome. Acta Haematologica 2023, 146: 287-292. PMID: 37166332, DOI: 10.1159/000530153.Peer-Reviewed Original ResearchConceptsAML/myelodysplastic syndromeAcute myeloid leukemiaInternational normalized ratioAntibacterial prophylaxisMyelodysplastic syndromeProphylactic antibacterialsCoagulation profileAcute myeloid leukemia/myelodysplastic syndromeDiagnosis of AMLHigher international normalized ratioLeukemia/myelodysplastic syndromePartial thromboplastin time prolongationYale-New Haven HospitalYale-New HavenRetrospective cohort studyAbnormal coagulation profileGroup of patientsTime of admissionHigh rateIndividual patient encountersInstitutional review boardAntibacterial exposureRelevant bleedingAdult patientsCohort study
2020
Diagnosis of Transient Ischemic Attack
Gocan S, Fitzpatrick T, Wang CQ, Taljaard M, Cheng W, Bourgoin A, Dowlatshahi D, Stotts G, Shamy M. Diagnosis of Transient Ischemic Attack. Stroke 2020, 51: 3371-3374. PMID: 32993462, DOI: 10.1161/strokeaha.120.031510.Peer-Reviewed Original ResearchConceptsTransient ischemic attackIschemic attackSex-specific differencesStroke diagnosisTIA/strokeUnilateral sensory lossRetrospective cohort studyStroke prevention clinicComplete patient recordsSex-based differencesStroke manifestationPrevention clinicCohort studySymptom onsetStroke symptomsPatient sexSensory lossFinal diagnosisMultinomial logistic regressionPatient recordsLogistic regressionDiagnosisSymptomsCandidate variablesSex
2019
A systematic review and meta-analysis evaluating geriatric consultation on older trauma patients.
Eagles D, Godwin B, Cheng W, Moors J, Figueira S, Khoury L, Fournier K, Lampron J. A systematic review and meta-analysis evaluating geriatric consultation on older trauma patients. Journal Of Trauma And Acute Care Surgery 2019, 88: 446-453. PMID: 31876691, DOI: 10.1097/ta.0000000000002571.Peer-Reviewed Original ResearchConceptsOlder trauma patientsGeriatric consultationHospital lengthOlder patientsTrauma centerSystematic reviewDelirium incidenceDischarge destinationTrauma patientsTrauma careStandard trauma carePatients 65 yearsNewcastle-Ottawa ScaleMeta-Analyses (PRISMA) guidelinesPreferred Reporting ItemsFull-text reviewHospital mortalityFirst systematic reviewCohort studyGeriatric assessmentGeriatric traumaIndependent reviewersInsufficient evidenceUnique citationsPatients