2024
A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections
Flatby H, Ravi A, Liyanarachi K, Afset J, Rasheed H, Brumpton B, Hveem K, Åsvold B, DeWan A, Solligård E, Damås J, Rogne T. A Genome-wide Association Study of Susceptibility to Upper Urinary Tract Infections. The Journal Of Infectious Diseases 2024, jiae231. PMID: 38713594, DOI: 10.1093/infdis/jiae231.Peer-Reviewed Original ResearchGenome-wide association studiesMichigan Genomics InitiativeAssociation studiesUpper UTIMendelian randomizationMR analysisUpper urinary tract infectionRisk factorsPotential causal risk factorsCardiometabolic risk factorsModifiable risk factorsSex-stratified analysesCausal risk factorUrinary tract infectionGenome-wideFemale-only analysisGenetic lociPotential causal relationshipGenome InitiativeHealth StudyUK BiobankHLA-DQA2LociTract infectionsSmoking score
2022
Incidence, recurring admissions and mortality of severe bacterial infections and sepsis over a 22-year period in the population-based HUNT study
Liyanarachi KV, Solligård E, Mohus RM, Åsvold BO, Rogne T, Damås JK. Incidence, recurring admissions and mortality of severe bacterial infections and sepsis over a 22-year period in the population-based HUNT study. PLOS ONE 2022, 17: e0271263. PMID: 35819970, PMCID: PMC9275692, DOI: 10.1371/journal.pone.0271263.Peer-Reviewed Original ResearchConceptsSevere bacterial infectionsPositive blood culturesBacterial infectionsBlood culturesPopulation-based HUNT StudyPositive blood culture rateTrøndelag Health StudyUrinary tract infectionPopulation-based cohortBlood culture rateCommon infectious diseasesInfectious disease burdenRegistry linkageTract infectionsLoss of healthMedian timeHUNT StudyDisease burdenIncidence rateCulture rateGeneral populationHealth StudyHospitalizationImportant causeTotal burden