Assessing spatial heterogeneity of multidrug-resistant tuberculosis in a high-burden country
Jenkins HE, Plesca V, Ciobanu A, Crudu V, Galusca I, Soltan V, Serbulenco A, Zignol M, Dadu A, Dara M, Cohen T. Assessing spatial heterogeneity of multidrug-resistant tuberculosis in a high-burden country. European Respiratory Journal 2012, 42: 1291-1301. PMID: 23100496, PMCID: PMC3800490, DOI: 10.1183/09031936.00111812.Peer-Reviewed Original ResearchConceptsMultidrug-resistant tuberculosisMDR-TB riskMDR-TB risk factorsNational TB surveillance dataMDR-TB incidenceTB surveillance dataMDR-TB casesHigh-burden countriesMDR-TB burdenDistribution of casesTB casesTuberculosis casesRisk of resistanceRisk factorsGreater riskSubstantial geographical variationSurveillance dataAppropriate targetingTesting coverageRiskTuberculosisBurdenHigh percentageLocal mechanismsPatients