2022
Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi
Khundi M, Carpenter JR, Corbett EL, Feasey HRA, Soko RN, Nliwasa M, Twabi H, Chiume L, Burke RM, Horton KC, Dodd PJ, Cohen T, MacPherson P. Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi. PLOS ONE 2022, 17: e0268749. PMID: 35605004, PMCID: PMC9126376, DOI: 10.1371/journal.pone.0268749.Peer-Reviewed Original ResearchConceptsCase notification ratesPrevalence surveyNotification ratioNeighbourhood prevalenceTB case notification ratesXpert MTB/RIFCase-finding interventionsTrue disease burdenChest X-ray screeningTB prevalence surveyTB surveillance systemMTB/RIFDiagnosis of tuberculosisSputum smear microscopyTB clinicTB patientsRespiratory infectionsTB prevalenceDisease burdenNotification ratesSmear microscopyX-ray screeningTuberculosisPrevalenceUrban tuberculosis
2020
Children as sentinels of tuberculosis transmission: disease mapping of programmatic data
Gunasekera KS, Zelner J, Becerra MC, Contreras C, Franke MF, Lecca L, Murray MB, Warren JL, Cohen T. Children as sentinels of tuberculosis transmission: disease mapping of programmatic data. BMC Medicine 2020, 18: 234. PMID: 32873309, PMCID: PMC7466499, DOI: 10.1186/s12916-020-01702-x.Peer-Reviewed Original ResearchConceptsNational Tuberculosis ProgrammeActive case-finding interventionsCase-finding interventionsTuberculosis transmissionNotification dataTuberculosis ProgrammeTuberculosis incidenceChild casesChildhood tuberculosis casesRecent transmission eventsProportion of casesCase notification dataMolecular epidemiological methodsMolecular epidemiologic methodsEndemic infectious diseasesTuberculosis casesProspective studyAdult casesDisease progressionNotification registerProgrammatic dataDistricts of LimaEpidemiological methodsInfectious diseasesTransmission hotspots