2019
Open versus Endovascular Repair of Abdominal Aortic Aneurysm
Lederle FA, Kyriakides TC, Stroupe KT, Freischlag JA, Padberg FT, Matsumura JS, Huo Z, Johnson GR. Open versus Endovascular Repair of Abdominal Aortic Aneurysm. New England Journal Of Medicine 2019, 380: 2126-2135. PMID: 31141634, DOI: 10.1056/nejmoa1715955.Peer-Reviewed Original ResearchConceptsEndovascular repair groupOpen repair groupEndovascular repairOpen repairOverall survivalAbdominal aortic aneurysmEuropean trialsAortic aneurysmLong-term overall survivalChronic obstructive lung diseaseWorse long-term outcomesAsymptomatic abdominal aortic aneurysmElective endovascular repairLow perioperative mortalityObstructive lung diseaseTraditional open repairAbdominal aortic aneurysms resultsLong-term outcomesLong-term resultsNumber of patientsLong-term survivalCause mortalityPerioperative mortalityPerioperative periodMore patients
2012
Long-Term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysm
Lederle FA, Freischlag JA, Kyriakides TC, Matsumura JS, Padberg FT, Kohler TR, Kougias P, Jean-Claude JM, Cikrit DF, Swanson KM. Long-Term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysm. New England Journal Of Medicine 2012, 367: 1988-1997. PMID: 23171095, DOI: 10.1056/nejmoa1207481.Peer-Reviewed Original ResearchConceptsEndovascular repair groupOpen repair groupAbdominal aortic aneurysmYears of ageEndovascular repairOpen repairLong-term survivalAortic aneurysmSimilar long-term survivalAsymptomatic abdominal aortic aneurysmVeterans Affairs Medical CenterElective endovascular repairLong-term morbidityTraditional open repairType of treatmentCause mortalityPerioperative mortalityTime of registrationOlder patientsYounger patientsEndovascular approachPrimary outcomeAneurysm ruptureMedical CenterSurvival advantageCost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial
Stroupe KT, Lederle FA, Matsumura JS, Kyriakides TC, Jonk YC, Ge L, Freischlag JA, Group O. Cost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial. Journal Of Vascular Surgery 2012, 56: 901-909.e2. PMID: 22640466, DOI: 10.1016/j.jvs.2012.01.086.Peer-Reviewed Original ResearchConceptsTotal health care costsEndovascular repair groupEndovascular groupHealth care providersHealth care costsRepair groupEndovascular repairMean total health care costsCare costsAbdominal aortic aneurysm repairPatient's health care providersVeterans Affairs Cooperative StudyHealth care utilization dataVA Health Economics Resource CenterOpen repair groupAortic aneurysm repairEndovascular AAA repairNon-VA careLength of stayAbdominal aortic aneurysmLower mean costQuality of lifeGraft costsMedicare data sourcesOVER trial
2009
Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial
Lederle FA, Freischlag JA, Kyriakides TC, Padberg FT, Matsumura JS, Kohler TR, Lin PH, Jean-Claude JM, Cikrit DF, Swanson KM, Peduzzi PN, Group F. Outcomes Following Endovascular vs Open Repair of Abdominal Aortic Aneurysm: A Randomized Trial. JAMA 2009, 302: 1535-1542. PMID: 19826022, DOI: 10.1001/jama.2009.1426.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, AbdominalBlood Vessel Prosthesis ImplantationCatheterization, PeripheralErectile DysfunctionFemaleHumansKaplan-Meier EstimateLength of StayMaleMiddle AgedMinimally Invasive Surgical ProceduresMorbidityPostoperative ComplicationsProportional Hazards ModelsQuality of LifeConceptsAbdominal aortic aneurysmOpen repairShort-term outcomesEndovascular repairPerioperative mortalityMajor morbidityAortic aneurysmProcedure failureTherapeutic proceduresIntensive care unit stayLong-term outcome dataVeterans Affairs Medical CenterElective endovascular repairEndovascular repair groupHealth-related qualityTraditional open repairElective AAA repairMedian procedure timeLength of stayMulticenter clinical trialQuality of lifeElective endovascularTransfusion requirementsUnit stayHospital stay