Maternal serum concentrations of per- and polyfluoroalkyl substances and childhood acute lymphoblastic leukemia
Jones R, Madrigal J, Troisi R, Surcel H, Öhman H, Kivelä J, Kiviranta H, Rantakokko P, Koponen J, Medgyesi D, McGlynn K, Sampson J, Albert P, Ward M. Maternal serum concentrations of per- and polyfluoroalkyl substances and childhood acute lymphoblastic leukemia. Journal Of The National Cancer Institute 2023, 116: 728-736. PMID: 38092046, PMCID: PMC11077307, DOI: 10.1093/jnci/djad261.Peer-Reviewed Original ResearchAcute lymphoblastic leukemiaLymphoblastic leukemiaOdds ratioChildhood acute lymphoblastic leukemiaFinnish Maternity CohortMaternal serum concentrationsMaternal serum levelsCommon childhood cancerConfidence intervalsConditional logistic regressionFirst trimester samplesChild sexPerfluorooctane sulfonic acidMaternal smokingGestational ageSerum levelsDiagnosis ageSerum concentrationsChildhood cancerCalendar periodFull-term offspringChildhood leukemiaMother's ageImmunotoxic propertiesLogistic regressionPrediagnostic serum concentrations of per‐ and polyfluoroalkyl substances and risk of papillary thyroid cancer in the Finnish Maternity Cohort
Madrigal J, Troisi R, Surcel H, Öhman H, Kivelä J, Kiviranta H, Rantakokko P, Koponen J, Medgyesi D, Kitahara C, McGlynn K, Sampson J, Albert P, Ward M, Jones R. Prediagnostic serum concentrations of per‐ and polyfluoroalkyl substances and risk of papillary thyroid cancer in the Finnish Maternity Cohort. International Journal Of Cancer 2023, 154: 979-991. PMID: 37902275, PMCID: PMC11286200, DOI: 10.1002/ijc.34776.Peer-Reviewed Original ResearchFinnish Maternity CohortPapillary thyroid cancerThyroid cancerOdds ratioPrediagnostic serum concentrationsPrediagnostic serum levelsConfidence intervalsCase-control studyConditional logistic regressionThyroid cancer riskPapillary thyroid cancer riskPerfluorononanoic acidPerfluorodecanoic acidPerfluorohexane sulfonic acidHigh exposure levelsMedian ageSerum levelsSerum concentrationsCalendar periodCancer riskBirth cohortThyroid glandLogistic regressionCancerClear association