2024
The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium
Gonzalez‐Palacios S, Compañ‐Gabucio L, Torres‐Collado L, Oncina‐Canovas A, García‐de‐la‐Hera M, Collatuzzo G, Negri E, Pelucchi C, Rota M, López‐Carrillo L, Lunet N, Morais S, Ward M, Martin V, Lozano‐Lorca M, Malekzadeh R, Pakseresht M, Hernández‐Ramírez R, Bonzi R, Patel L, López‐Cervantes M, Rabkin C, Tsugane S, Hidaka A, Trichopoulou A, Karakatsani A, Camargo M, Curado M, Zhang Z, La Vecchia C, Boffetta P, Vioque J. The protective effect of dietary folate intake on gastric cancer is modified by alcohol consumption: A pooled analysis of the StoP Consortium. International Journal Of Cancer 2024, 155: 1367-1375. PMID: 38757245, PMCID: PMC11326987, DOI: 10.1002/ijc.35004.Peer-Reviewed Original ResearchDietary folate intakeHigh folate intakeFolate intakeRisk of GCOdds ratioGastric cancerAlcoholic drinks/dayAlcohol consumptionEffect of dietary folate intakeEffect of folate intakeQuartile of folate intakeFood frequency questionnaireCalculate adjusted odds ratiosCase-control studyConfidence intervalsAdjusted odds ratiosFrequency questionnaireGC casesGC riskPooled analysisQuartile incrementLowest quartileLow riskLinear mixed modelsModifiable factorsThe association between dietary fiber intake and gastric cancer: a pooled analysis of 11 case–control studies
Collatuzzo G, Cortez Lainez J, Pelucchi C, Negri E, Bonzi R, Palli D, Ferraroni M, Zhang Z, Yu G, Lunet N, Morais S, López-Carrillo L, Zaridze D, Maximovitch D, Guevara M, Santos-Sanchez V, Vioque J, Garcia de la Hera M, Ward M, Malekzadeh R, Pakseresht M, Hernández-Ramírez R, Turati F, Rabkin C, Liao L, Sinha R, López-Cervantes M, Tsugane S, Hidaka A, Camargo M, Curado M, Zubair N, Kristjansson D, Shah S, La Vecchia C, Boffetta P. The association between dietary fiber intake and gastric cancer: a pooled analysis of 11 case–control studies. European Journal Of Nutrition 2024, 63: 1857-1865. PMID: 38687390, PMCID: PMC11329417, DOI: 10.1007/s00394-024-03388-w.Peer-Reviewed Original ResearchDietary fiber intakeCase-control studyFiber intakeQuartiles of dietary fiber intakeOdds ratioStomach cancer PoolingHospital-based case-control studyQuartile of fiber intakeConfidence intervalsFood frequency questionnaireHistological typeMethodsWe pooled dataIntake of dietary fiberMultivariate logistic regression modelAnatomical sitesLogistic regression modelsVegetable intakeResultsThe ORCancer mortalityFrequency questionnaireSocioeconomic statusStratified analysisDietary factorsRegression modelsPooled analysis
2023
Yoghurt Intake and Gastric Cancer: A Pooled Analysis of 16 Studies of the StoP Consortium
Collatuzzo G, Negri E, Pelucchi C, Bonzi R, Turati F, Rabkin C, Liao L, Sinha R, Palli D, Ferraroni M, López-Carrillo L, Lunet N, Morais S, Albanes D, Weinstein S, Parisi D, Zaridze D, Maximovitch D, Dierssen-Sotos T, Jiménez-Moleón J, Vioque J, de la Hera M, Curado M, Dias-Neto E, Hernández-Ramírez R, López-Cervantes M, Ward M, Tsugane S, Hidaka A, Lagiou A, Lagiou P, Zhang Z, Trichopoulou A, Karakatsani A, Camargo M, La Vecchia C, Boffetta P. Yoghurt Intake and Gastric Cancer: A Pooled Analysis of 16 Studies of the StoP Consortium. Nutrients 2023, 15: 1877. PMID: 37111097, PMCID: PMC10147010, DOI: 10.3390/nu15081877.Peer-Reviewed Original ResearchConceptsGastric cancerYoghurt intakeYoghurt consumptionOdds ratioMultivariable unconditional logistic regression modelStomach cancer Pooling (StoP) ProjectStudy-specific odds ratiosUnconditional logistic regression modelsFood frequency questionnairePopulation-based studyConfidence intervalsIntestinal gastric cancerLogistic regression modelsFrequency questionnaireIntestinal casesPooled analysisProtective effectPooling ProjectGut microbiotaGC casesDisease riskGC riskAdditional studiesIntakeCardia
2022
Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled Analysis of Case-Control Studies of the Stop Consortium
Collatuzzo G, Teglia F, Pelucchi C, Negri E, Rabkin CS, Liao LM, Sinha R, López-Carrillo L, Lunet N, Morais S, Aragonés N, Moreno V, Vioque J, de la Hera M, Ward MH, Malekzadeh R, Pakseresht M, Hernández-Ramírez RU, López-Cervantes M, Bonzi R, Dalmartello M, Tsugane S, Hidaka A, Camargo MC, Curado MP, Zhang ZF, Zubair N, La Vecchia C, Shah S, Boffetta P. Inverse Association between Dietary Iron Intake and Gastric Cancer: A Pooled Analysis of Case-Control Studies of the Stop Consortium. Nutrients 2022, 14: 2555. PMID: 35745285, PMCID: PMC9228527, DOI: 10.3390/nu14122555.Peer-Reviewed Original ResearchConceptsDietary iron intakeCase-control studyIron intakeGastric cancerHistological typeOdds ratioDietary ironMultivariable unconditional logistic regression modelStomach cancer Pooling (StoP) ProjectTotal dietary iron intakeFruit/vegetable intakeUnconditional logistic regression modelsNon-cardia gastric cancerFood frequency questionnaireConfidence intervalsLogistic regression modelsAnatomical subsitesFrequency questionnaireSalt intakeSmoking statusPooled analysisIntestinal typeVegetable intakeInverse associationCaloric intakeThe mediating role of combined lifestyle factors on the relationship between education and gastric cancer in the Stomach cancer Pooling (StoP) Project
Alicandro G, Bertuccio P, Collatuzzo G, Pelucchi C, Bonzi R, Liao LM, Rabkin CS, Sinha R, Negri E, Dalmartello M, Zaridze D, Maximovich D, Vioque J, Garcia de la Hera M, Tsugane S, Hidaka A, Hamada GS, López-Carrillo L, Hernández-Ramírez RU, Malekzadeh R, Pourfarzi F, Zhang ZF, Kurtz RC, Camargo MC, Curado MP, Lunet N, Boffetta P, La Vecchia C. The mediating role of combined lifestyle factors on the relationship between education and gastric cancer in the Stomach cancer Pooling (StoP) Project. British Journal Of Cancer 2022, 127: 855-862. PMID: 35624300, PMCID: PMC9427973, DOI: 10.1038/s41416-022-01857-9.Peer-Reviewed Original ResearchConceptsLifestyle factorsGastric cancerOdds ratioStomach cancer Pooling (StoP) ProjectWarrants further investigationNatural direct effectNatural indirect effectReduced riskPooling ProjectReference categoryGC casesLower educationComplete dataCausal pathwaysCancerFurther investigationDirect effectMediation analysisLow levelsIndirect effectsPotential pathwaysMediation effectFactorsPathwayTea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium
Martimianaki G, Alicandro G, Pelucchi C, Bonzi R, Rota M, Hu J, Johnson KC, Rabkin CS, Liao LM, Sinha R, Zhang ZF, Dalmartello M, Lunet N, Morais S, Palli D, Ferraroni M, Yu GP, Tsugane S, Hidaka A, Curado MP, Dias-Neto E, Zaridze D, Maximovitch D, Vioque J, Garcia de la Hera M, López-Carrillo L, Hernández-Ramírez RU, Hamada GS, Ward MH, Mu L, Malekzadeh R, Pourfarzi F, Trichopoulou A, Karakatsani A, Kurtz RC, Lagiou A, Lagiou P, Boccia S, Boffetta P, Camargo MC, Negri E, La Vecchia C. Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium. British Journal Of Cancer 2022, 127: 726-734. PMID: 35610368, PMCID: PMC9381730, DOI: 10.1038/s41416-022-01856-w.Peer-Reviewed Original ResearchConceptsStomach cancer pooling (StoP) project consortiumCups/dayGastric cancerTea consumptionInverse associationOdds ratioTea drinkersH. pylori infectionGastric cardia cancerWeak inverse associationConfidence intervalsStrong inverse associationRegular tea drinkersNon-regular drinkersGastric cancer riskCardia cancerPylori infectionRisk factorsCancer riskEpidemiological studiesRegular drinkersConclusionOur resultsTea drinkingCancerDrinkersAllium vegetables intake and the risk of gastric cancer in the Stomach cancer Pooling (StoP) Project
Dalmartello M, Turati F, Zhang ZF, Lunet N, Rota M, Bonzi R, Galeone C, Martimianaki G, Palli D, Ferraroni M, Yu GP, Morais S, Malekzadeh R, López-Carrillo L, Zaridze D, Maximovitch D, Aragonés N, Fernández-Tardón G, Martin V, Vioque J, Garcia de la Hera M, Curado MP, Coimbra FJF, Assumpcao P, Pakseresht M, Hu J, Hernández-Ramírez RU, Ward MH, Pourfarzi F, Mu L, Tsugane S, Hidaka A, Lagiou P, Lagiou A, Trichopoulou A, Karakatsani A, Boffetta P, Camargo MC, Negri E, La Vecchia C, Pelucchi C. Allium vegetables intake and the risk of gastric cancer in the Stomach cancer Pooling (StoP) Project. British Journal Of Cancer 2022, 126: 1755-1764. PMID: 35210588, PMCID: PMC9174191, DOI: 10.1038/s41416-022-01750-5.Peer-Reviewed Original ResearchConceptsStomach cancer Pooling (StoP) ProjectAllium vegetablesOdds ratioInverse associationPooling ProjectStudy-specific odds ratiosGC riskAllium vegetable intakePooled odds ratioGastric cancer riskIndividual participant dataHeterogeneity of resultsVegetable intakeGastric cancerHigh intakeCancer riskEpidemiological studiesGC casesParticipant dataStrong associationSubstantial heterogeneityRiskIntakeAssociationVegetablesIdentifying the profile of Helicobacter pylori negative gastric cancers: a case only analysis within the Stomach cancer Pooling (StoP) Project
Morais S, Peleteiro B, Araújo N, Malekzadeh R, Ye W, Plymoth A, Tsugane S, Hidaka A, Hamada GS, López-Carrillo L, Zaridze D, Maximovich D, Aragonés N, Castaño-Vinyals G, Pakseresht M, Hernández-Ramírez RU, López-Cervantes M, Leja M, Gasenko E, Pourfarzi F, Zhang ZF, Yu GP, Derakhshan MH, Pelucchi C, Negri E, La Vecchia C, Lunet N. Identifying the profile of Helicobacter pylori negative gastric cancers: a case only analysis within the Stomach cancer Pooling (StoP) Project. Cancer Epidemiology Biomarkers & Prevention 2022, 31: cebp.0402.2021. PMID: 34728467, DOI: 10.1158/1055-9965.epi-21-0402.Peer-Reviewed Original ResearchConceptsStomach cancer Pooling (StoP) ProjectGastric cancerNegative gastric cancerGastric atrophyRisk factorsOdds ratioFamily historyPooling ProjectPositive casesGastric cancer risk factorsInfection statusNon-cardia gastric cancerCancer risk factorsFirst-degree relativesHigh-risk profileAbsence of infectionOccurrence of cancerCurrent smokersPooled prevalenceCagA statusHpNGCSerologic testsLow prevalenceAdvanced stageCancer
2021
Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium
Martimianaki G, Bertuccio P, Alicandro G, Pelucchi C, Bravi F, Carioli G, Bonzi R, Rabkin CS, Liao LM, Sinha R, Johnson K, Hu J, Palli D, Ferraroni M, Lunet N, Morais S, Tsugane S, Hidaka A, Hamada GS, López-Carrillo L, Hernández-Ramírez RU, Zaridze D, Maximovitch D, Aragonés N, Martin V, Ward MH, Vioque J, de la Hera M, Zhang ZF, Kurtz RC, Lagiou P, Lagiou A, Trichopoulou A, Karakatsani A, Malekzadeh R, Camargo MC, Curado MP, Boccia S, Boffetta P, Negri E, La Vecchia C. Coffee consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling Project consortium. European Journal Of Cancer Prevention 2021, 31: 117-127. PMID: 34545022, PMCID: PMC8972971, DOI: 10.1097/cej.0000000000000680.Peer-Reviewed Original ResearchConceptsPooled odds ratioGastric cancerCoffee drinkersOdds ratioCoffee intakeCoffee consumptionStomach cancer pooling (StoP) project consortiumHigh coffee intakeGastric cardia cancerConfidence intervalsHeavy coffee drinkersDose-response relationshipLogistic mixed-effects modelsCardia cancerMore cupsRisk factorsObservational studyRare drinkersCancerAvailable evidenceMixed-effects modelsDrinkersRelevant associationsRandom interceptPositive associationExploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project
Collatuzzo G, Pelucchi C, Negri E, López‐Carrillo L, Tsugane S, Hidaka A, Hamada G, Hernández‐Ramírez R, López‐Cervantes M, Malekzadeh R, Pourfarzi F, Mu L, Zhang Z, Lunet N, La Vecchia C, Boffetta P. Exploring the interactions between Helicobacter pylori (Hp) infection and other risk factors of gastric cancer: A pooled analysis in the Stomach cancer Pooling (StoP) Project. International Journal Of Cancer 2021, 149: 1228-1238. PMID: 33990950, DOI: 10.1002/ijc.33678.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStomach cancer Pooling (StoP) ProjectHP infectionRisk factorsGastric cancerSocioeconomic statusCigarette smokingPooled analysisAlcohol drinkingOdds ratioPooling ProjectMultivariate unconditional logistic regressionDietary salt intakeModifiable risk factorsHelicobacter pylori infectionUnconditional logistic regressionGastric cancer preventionConfidence intervalsCase-control studySummary odds ratiosLifestyle modificationHP eradicationSalt intakeTobacco smokingDietary saltHistologic type
2019
Smoking and Helicobacter pylori infection
Ferro A, Morais S, Pelucchi C, Aragonés N, Kogevinas M, López-Carrillo L, Malekzadeh R, Tsugane S, Hamada GS, Hidaka A, Hernández-Ramírez RU, López-Cervantes M, Zaridze D, Maximovitch D, Pourfarzi F, Zhang ZF, Yu GP, Pakseresht M, Ye W, Plymoth A, Leja M, Gasenko E, Derakhshan MH, Negri E, La Vecchia C, Peleteiro B, Lunet N. Smoking and Helicobacter pylori infection. European Journal Of Cancer Prevention 2019, Publish Ahead of Print: &na;. PMID: 30272597, DOI: 10.1097/cej.0000000000000471.Peer-Reviewed Original ResearchConceptsH. pylori seropositivityHelicobacter pylori infectionPylori infectionPylori seropositivityPrevalence ratiosStomach cancer Pooling (StoP) ProjectDuration of smokingH. pylori infectionCase-control studyConfidence intervalsSummary odds ratiosIndividual participant dataOdds ratioEgger's testGastric cancerStratified analysisMajor covariatesPooling ProjectGreater prevalenceSmokingH. pyloriSignificant associationPublication biasSeropositivityInfectionSex differences in the prevalence of Helicobacter pylori infection: an individual participant data pooled analysis (StoP Project)
Ferro A, Morais S, Pelucchi C, Dierssen-Sotos T, Martín V, López-Carrillo L, Malekzadeh R, Tsugane S, Hamada GS, Hidaka A, Hernández-Ramírez RU, López-Cervantes M, Zaridze D, Maximovitch D, Pourfarzi F, Zhang ZF, Yu GP, Pakseresht M, Ye W, Plymoth A, Leja M, Gasenko E, Derakhshan MH, Negri E, La Vecchia C, Peleteiro B, Lunet N. Sex differences in the prevalence of Helicobacter pylori infection: an individual participant data pooled analysis (StoP Project). European Journal Of Gastroenterology & Hepatology 2019, 31: 593-598. PMID: 30839435, DOI: 10.1097/meg.0000000000001389.Peer-Reviewed Original ResearchConceptsH. pylori infectionHelicobacter pylori infectionPylori infectionPrevalence ratiosOdds ratioGastric atrophyIgG serum antibody titersStomach cancer Pooling (StoP) ProjectPublication biasInfection statusSerum antibody titersConfidence intervalsSummary odds ratiosSerum pepsinogen levelsIndividual participant dataLifetime infectionsMultiplex serologyAntibody titersHistological examinationPooling ProjectPepsinogen levelsOlder controlsInfectionParticipant dataStrong associationEducation and gastric cancer risk—An individual participant data meta‐analysis in the StoP project consortium
Rota M, Alicandro G, Pelucchi C, Bonzi R, Bertuccio P, Hu J, Zhang Z, Johnson KC, Palli D, Ferraroni M, Yu G, Galeone C, López‐Carrillo L, Muscat J, Lunet N, Ferro A, Ye W, Plymoth A, Malekzadeh R, Zaridze D, Maximovitch D, Kogevinas M, de Larrea N, Vioque J, Navarrete‐Muñoz E, Tsugane S, Hamada GS, Hidaka A, Pakseresht M, Wolk A, Håkansson N, Hernández‐Ramírez R, López‐Cervantes M, Ward M, Pourfarzi F, Mu L, Kurtz RC, Lagiou A, Lagiou P, Boffetta P, Boccia S, Negri E, La Vecchia C. Education and gastric cancer risk—An individual participant data meta‐analysis in the StoP project consortium. International Journal Of Cancer 2019, 146: 671-681. PMID: 30919464, DOI: 10.1002/ijc.32298.Peer-Reviewed Original ResearchConceptsGastric cancer riskIndividual participant dataOdds ratioCancer riskSocioeconomic positionHighest household income categoryStomach cancer Pooling (StoP) ProjectStudy-specific odds ratiosH. pylori-negative subjectsGC riskParticipant dataPylori-negative subjectsStrong risk factorRandom-effects meta-analytic modelConfidence intervalsPooled odds ratioStrong inverse associationLow socioeconomic positionPublic health interventionsHousehold income categoryNegative subjectsInverse associationRisk factorsPooling ProjectPremature mortalityCitrus fruit intake and gastric cancer: The stomach cancer pooling (StoP) project consortium
Bertuccio P, Alicandro G, Rota M, Pelucchi C, Bonzi R, Galeone C, Bravi F, Johnson KC, Hu J, Palli D, Ferraroni M, López‐Carrillo L, Lunet N, Ferro A, Malekzadeh R, Zaridze D, Maximovitch D, Vioque J, Navarrete‐Munoz E, Pakseresht M, Hernández‐Ramírez R, López‐Cervantes M, Ward M, Pourfarzi F, Tsugane S, Hidaka A, Zhang Z, Kurtz RC, Lagiou P, Lagiou A, Boffetta P, Boccia S, Negri E, La Vecchia C. Citrus fruit intake and gastric cancer: The stomach cancer pooling (StoP) project consortium. International Journal Of Cancer 2019, 144: 2936-2944. PMID: 30521095, DOI: 10.1002/ijc.32046.Peer-Reviewed Original ResearchConceptsCitrus fruit intakeStomach cancer pooling (StoP) project consortiumGastric cancerFruit intakeOdds ratioPrevious cohort studiesServings/weekConfidence intervalsCase-control studyCitrus fruit consumptionGastric cancer riskCohort studyInverse associationRisk factorsProtective effectCitrus fruitsCancer riskHighest thirdNull associationProtective roleLinear mixed effects modelsCancerFruit consumptionFavorable effectMixed effects models