Sodium arsenite alters cell cycle and MTHFR, MT1/2, and c-Myc protein levels in MCF-7 cells
Ruiz-Ramos R, López-Carrillo L, Albores A, Hernández-Ramírez RU, Cebrian ME. Sodium arsenite alters cell cycle and MTHFR, MT1/2, and c-Myc protein levels in MCF-7 cells. Toxicology And Applied Pharmacology 2009, 241: 269-274. PMID: 19766132, DOI: 10.1016/j.taap.2009.09.006.Peer-Reviewed Original ResearchConceptsC-Myc protein levelsProtein levelsC-MycInduction of genesMCF-7 cellsHigher DNA synthesis rateMTHFR protein levelsAlters cell cycleBreast epithelial cellsArsenite treatmentGrowth regulationMethylenetetrahydrofolate reductaseCell cycleC-Myc overexpressionFolate cycleDNA synthesis rateBrdU-stained cellsEffects of arsenicCell proliferationHuman populationSodium arseniteEpithelial cellsCell viabilityMT1/2Arsenite concentration