A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain
Toll BA, Leary V, Wu R, Salovey P, Meandzija B, O'Malley SS. A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain. Addictive Behaviors 2007, 33: 173-179. PMID: 17587504, PMCID: PMC2488403, DOI: 10.1016/j.addbeh.2007.05.012.Peer-Reviewed Original ResearchConceptsPost-cessation weight gainWeight-concerned smokersPoint prevalence abstinenceWeight gainAbstinent participantsSustained-release bupropion hydrochlorideHigher smoking cessation ratesWeight suppressant effectsOpen-label studyPercentage of patientsSmoking cessation ratesLess weight gainDays of treatmentNaltrexone augmentationAdverse eventsCombination pharmacotherapyPrimary outcomeCessation ratesTreatment regimenCigarette smokersClinical trialsContinuous abstinenceLabel studyPsychosocial interventionsBupropion