2001
Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches
Spahn T, Fontana A, Faria A, Slavin A, Eugster H, Zhang X, Koni P, Ruddle N, Flavell R, Rennert P, Weiner H. Induction of oral tolerance to cellular immune responses in the absence of Peyer's patches. European Journal Of Immunology 2001, 31: 1278-1287. PMID: 11298355, DOI: 10.1002/1521-4141(200104)31:4<1278::aid-immu1278>3.0.co;2-a.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAnimalsAntibodiesDose-Response Relationship, ImmunologicEnzyme-Linked Immunosorbent AssayFecesGene DeletionHypersensitivity, DelayedImmune ToleranceImmunity, MucosalImmunoglobulin AInterferon-gammaInterleukin-2Lymph NodesLymphotoxin-alphaMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutOvalbuminPeyer's PatchesSignal TransductionTumor Necrosis Factor-alphaConceptsGut-associated lymphoid tissueMesenteric lymph nodesOral toleranceLow-dose oral toleranceDelayed-type hypersensitivity responseFecal IgA productionLTbeta-/- miceOral tolerance inductionLamina propria lymphocytesIntact immune systemCellular immune responsesPeripheral lymphoid organsIFN-gamma productionTumor necrosis factor familyProcessing of antigensNecrosis factor familySystemic hyporesponsivenessLymph nodesHypersensitivity responseTolerance inductionIgA productionIntraperitoneal administrationLymphoid organsLymphoid tissuePeyer's patches
1977
Role of Endogenous Murine Leukemia Virus in Immunologically Triggered Lymphoreticular Tumors. I. Development and Use of Oncogenic Cellfree Preparations Serially Passaged In Vivo2
Armstrong M, Ruddle N, Lipman M, Pierce S, Richards F. Role of Endogenous Murine Leukemia Virus in Immunologically Triggered Lymphoreticular Tumors. I. Development and Use of Oncogenic Cellfree Preparations Serially Passaged In Vivo2. Journal Of The National Cancer Institute 1977, 58: 67-72. PMID: 13227, DOI: 10.1093/jnci/58.1.67.Peer-Reviewed Original ResearchConceptsLymphoreticular tumorsB-tropic MuLVSyngeneic miceBALB/Reticular tissueMurine leukemia virusYoung adult recipientsLatent periodNormal control miceLeukemia virusEndogenous murine leukemia virusMean latent periodImmunologic disturbancesAdult recipientsControl miceMuLV replicationHost reactionGVHRTumorsMiceB-tropic murine leukemia virusSerial passageCellfree extractsMuLVVirus
1976
Separation and analysis of differentiating B lymphocytes from mouse spleens
Hecht T, Ruddle N, Ruddle F. Separation and analysis of differentiating B lymphocytes from mouse spleens. Cellular Immunology 1976, 22: 193-210. PMID: 1084225, DOI: 10.1016/0008-8749(76)90023-x.Peer-Reviewed Original Research