2024
IgG Isotypes Targeting a Recombinant Chimeric Protein of Trypanosoma cruzi in Different Clinical Presentations of Chronic Chagas Disease
Serrano I, Ribeiro G, Santos R, Cruz J, Lanza F, dos Santos E, de Almeida M, de Souza Soares J, Luquetti A, Celedon P, Zanchin N, Santos F, dos Reis M. IgG Isotypes Targeting a Recombinant Chimeric Protein of Trypanosoma cruzi in Different Clinical Presentations of Chronic Chagas Disease. American Journal Of Tropical Medicine And Hygiene 2024, 110: 669-676. PMID: 38412539, PMCID: PMC10993828, DOI: 10.4269/ajtmh.23-0652.Peer-Reviewed Original ResearchClinical presentationChronic CDClinical formsSpectrum of clinical presentationsIg profilesSevere cardiac involvementChagas diseaseChronic Chagas diseaseSerum samplesDevelopment of tissue damageHost immune responseCross-sectional studyCardiac involvementIgG3 levelsImmunopathogenic mechanismsDisease progressionProgression of CDRecombinant chimeric proteinImmune responseIgG isotypeIgG3 isotypesTotal IgGMC groupSC groupDisease pathogenesis
2020
Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil
Ferreira V, Ferreira Í, Chang H, Nunes A, Topaz N, Pimentel E, Moura A, Ribeiro G, Feitosa C, Reis M, Wang X, Campos L. Meningococcal carriage in young adults six years after meningococcal C conjugate (MCC) vaccine catch-up campaign in Salvador, Brazil. Vaccine 2020, 38: 2995-3002. PMID: 32115294, DOI: 10.1016/j.vaccine.2020.02.050.Peer-Reviewed Original ResearchConceptsMeningococcal carriageCarriage prevalenceRT-PCRN. meningitidisYoung adultsMeningococcal carriage studyMeningococcal serogroup CCross-sectional studyMeningococcal carriage prevalenceAppropriate vaccination strategiesStandard microbiology methodsSix yearsMeningococcal carriage isolatesNG isolatesMale sexSerogroup CHerd protectionVaccination strategiesCarriage isolatesCarriage studiesOropharyngeal swabsReal-time PCRNull genotypeContinuous vaccinationNeisseria meningitidis
2019
8. Factors Associated with Group A Streptococcus emm Type Diversifi cation in a Large Urban Setting in Brazil: A Cross-Sectional Study
Tartof S, Reis J, Andrade A, Ramos R, Reis M, Riley L. 8. Factors Associated with Group A Streptococcus emm Type Diversifi cation in a Large Urban Setting in Brazil: A Cross-Sectional Study. 2019, 134-148. DOI: 10.1525/9780520962798-013.Peer-Reviewed Original Research
2011
Biomarkers of Hemolysis and Inflammation in Sickle Cell Disease Children: Association with Nasopharynx and Oropharynx Bacteria colonization
Rocha L, Seixas M, Cerqueira B, Lopes V, Reis M, Goncalves M. Biomarkers of Hemolysis and Inflammation in Sickle Cell Disease Children: Association with Nasopharynx and Oropharynx Bacteria colonization. Blood 2011, 118: 2140. DOI: 10.1182/blood.v118.21.2140.2140.Peer-Reviewed Original ResearchHigh ferritin serum levelsFerritin serum levelsSCD patientsSerum levelsS. pneumoniaeNasopharyngeal colonizationNasopharynx colonizationHbSS genotypeSickle cell disease childrenS. aureusBacteria colonizationBiomarkers of hemolysisHigher leukocyte numbersPneumococcal penicillin resistanceHigher neutrophil countS. pneumoniae colonizationCause of infectionCross-sectional studyOccurrence of infectionMultivariate analysis modelNeutrophil countSCD childrenHigh ferritinPneumonia occurrencePneumoniae colonization
2010
Iinsulin Levels and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) May Explain a Possible Important Role of the Pancreas In Sickle Cell Disease Patients Outcome
Seixas M, Lopes V, Cezar R, Carvalho G, Rocha L, Lyra I, Reis M, Goncalves M. Iinsulin Levels and Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) May Explain a Possible Important Role of the Pancreas In Sickle Cell Disease Patients Outcome. Blood 2010, 116: 4811. DOI: 10.1182/blood.v116.21.4811.4811.Peer-Reviewed Original ResearchSickle cell diseaseC-reactive proteinInsulin levelsBlood cell countSCD patientsAspartate aminotransferaseHOMA-IRWBC countLactate dehydrogenaseHemoglobin concentrationCell countSeverity of SCDChronic sub-clinical inflammationWhite blood cell countSub-clinical inflammationHigher insulin levelsRed blood cell countCross-sectional studyLower insulin levelsHigher ferritin concentrationsHigher haptoglobin concentrationsImportant biomarkerInflammatory markersPain episodesChronic inflammation
2009
Associação entre déficit de crescimento e retardo maturacional de crianças e adolescentes infectados
Alves T, de Cássia Ribeiro Silva R, Assis A, da Silva M, de Santana M, Barreto M, Reis M, Parraga I, Blanton R. Associação entre déficit de crescimento e retardo maturacional de crianças e adolescentes infectados. Revista De Nutrição 2009, 22: 309-318. DOI: 10.1590/s1415-52732009000300001.Peer-Reviewed Original ResearchDevelopmental delayCity of JequiéHelminth-infected childrenSocioeconomic statusMultivariate logistic regressionCross-sectional studyPrevalence of stuntingGrowth-related hormonesStool testingPubertal delayInadequate nutritionLogistic regressionHealth conditionsIntervention strategiesFamily socioeconomic statusStage assessmentCrianças eNutritionAssociationSanitary conditionsSubjectsMalnutritionPrevalenceHormoneProper development
2007
Detection of antinucleosome antibodies in systemic lupus erythematosus
Lima I, Barbosa L, Lopes M, Reis E, Reis M, Colossi K, Abreu M, Ferreira C, Santiago M. Detection of antinucleosome antibodies in systemic lupus erythematosus. Advances In Rheumatology 2007, 47: 160-164. DOI: 10.1590/s0482-50042007000300004.Peer-Reviewed Original ResearchDiagnosis of SLESystemic lupus erythematosusSystemic sclerosisDisease activitySLEDAI scoreLupus erythematosusAntinucleosome antibodiesSLE samplesDisease activity indexCross-sectional studyAnti-DNA antibodiesMean age 35Lack of associationMyositis patientsRheumatology criteriaRheumatologic practiceSLE patientsAge 35American CollegeActivity indexPatientsDiagnosisAntibodiesDiagnostic performanceELISA system
2006
Prevalence of hepatitis C virus (HCV) infection and HCV genotypes of hemodialysis patients in Salvador, Northeastern Brazil
Silva L, Silva M, Rodart I, Lopes G, Costa F, Melo M, Gusmão E, Reis M. Prevalence of hepatitis C virus (HCV) infection and HCV genotypes of hemodialysis patients in Salvador, Northeastern Brazil. Brazilian Journal Of Medical And Biological Research 2006, 39: 595-602. PMID: 16648896, DOI: 10.1590/s0100-879x2006000500005.Peer-Reviewed Original ResearchConceptsHepatitis C virus infectionCandidate blood donorsC virus infectionHD patientsHCV infectionBlood donorsGenotype 1Virus infectionAnti-HCV seroprevalenceAnti-HCV prevalenceHCV genotype distributionAnti-HCV antibodiesHCV genotype 1Chronic liver diseaseTransfusion-transmitted infectionsCross-sectional studyDifferent dialysis centresHCV seroprevalenceChronic hemodialysisHemodialysis populationHCV RNAPositive patientsHemodialysis patientsHCV genotypesLiver disease
2004
Childhood stunting in Northeast Brazil: the role of Schistosoma mansoni infection and inadequate dietary intake
Assis A, Prado M, Barreto M, Reis M, Conceição Pinheiro S, Parraga I, Blanton R. Childhood stunting in Northeast Brazil: the role of Schistosoma mansoni infection and inadequate dietary intake. European Journal Of Clinical Nutrition 2004, 58: 1022-1029. PMID: 15220944, DOI: 10.1038/sj.ejcn.1601926.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnimalsBody HeightBrazilChildChild DevelopmentChild Nutritional Physiological PhenomenaCross-Sectional StudiesDietDietary CarbohydratesDietary FatsDietary ProteinsEnergy IntakeFecesFemaleGrowth DisordersHumansIntestinal Diseases, ParasiticLogistic ModelsMaleSchistosomiasis mansoniConceptsSchistosoma mansoni infectionS. mansoni infectionInadequate dietary intakeMansoni infectionDietary intakeS. mansoniHeavy S. mansoni infectionS. mansoni endemic areasDevelopment of stuntingRisk of stuntingCross-sectional studyUninfected childrenNutritional interventionDietary measuresInadequate intakeCarbohydrate intakeStool samplesHigh riskMedian proteinEndemic areasParasitic infectionsCaloric consumptionChildhood stuntingAge groupsAdequate diet