2023
Prevalence of Genotypic Resistance Mutations in Patients with Chronic Hepatitis B (HBV) Treated with Entecavir and Tenofovir in Two Reference Centers in the North and Northeast of Brazil
Pacheco S, Schinoni M, Stocker A, Paraná R, Reis M, Silva L. Prevalence of Genotypic Resistance Mutations in Patients with Chronic Hepatitis B (HBV) Treated with Entecavir and Tenofovir in Two Reference Centers in the North and Northeast of Brazil. Medical Research Archives 2023, 11 DOI: 10.18103/mra.v11i3.3473.Peer-Reviewed Original ResearchGenotypic resistance mutationsResistance mutationsHepatitis BChronic hepatitis BFirst-line treatmentVaccine escape mutationsHepatitis B virusChronic HBVAntiviral treatmentLine treatmentLiver diseaseTherapeutic managementB virusEscape mutationsGenotypic resistanceReference centerPatientsGenetic mutationsEntecavirHBVTenofovirTreatmentNortheast of BrazilPresent studyNucleotide analogues
2021
Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors
Rodart I, Pares M, Mendes A, Accardo C, Martins J, Silva C, Carvalho F, Barreto J, Reis M, Tersariol I, Nader H. Diagnostic Accuracy of Serum Hyaluronan for Detecting HCV Infection and Liver Fibrosis in Asymptomatic Blood Donors. Molecules 2021, 26: 3892. PMID: 34202190, PMCID: PMC8270308, DOI: 10.3390/molecules26133892.Peer-Reviewed Original ResearchConceptsHepatitis C virusAsymptomatic blood donorsLiver fibrosisBlood donorsSerum hyaluronanHCV infectionSerum levelsGGT serum levelsHA serum levelsHCV RNA detectionHCV viral loadProgressive liver diseaseAdvanced liver fibrosisHigher ALT levelsSignificant liver fibrosisNormal ALTHCV viremiaALT levelsAntiviral treatmentAsymptomatic personsBiopsy confirmationHCV samplesLiver biomarkersLiver diseaseViral load