2002
Identification of the Lipooligosaccharide Biosynthesis Gene lic2B as a Putative Virulence Factor in Strains of Nontypeable Haemophilus influenzae That Cause Otitis Media
Pettigrew M, Foxman B, Marrs C, Gilsdorf J. Identification of the Lipooligosaccharide Biosynthesis Gene lic2B as a Putative Virulence Factor in Strains of Nontypeable Haemophilus influenzae That Cause Otitis Media. Infection And Immunity 2002, 70: 3551-3556. PMID: 12065495, PMCID: PMC128108, DOI: 10.1128/iai.70.7.3551-3556.2002.Peer-Reviewed Original ResearchConceptsMiddle ear isolatesNT H. influenzaeOtitis mediaH. influenzaeEar isolatesThroat isolatesHaemophilus influenzaeMiddle earAcute otitis mediaDay careNontypeable Haemophilus influenzaeVirulence factorsSpecific virulence factorsType B isolatesOM pathogenesisPutative virulence factorsH. influenzae geneImportant causeClinical isolatesPathogenic processesInfluenzaeB isolatesAcid levelsAmino acid levelsNontypeable
2000
Wolbachia neither induces nor suppresses transcripts encoding antimicrobial peptides
Bourtzis K, Pettigrew M, O’Neill S. Wolbachia neither induces nor suppresses transcripts encoding antimicrobial peptides. Insect Molecular Biology 2000, 9: 635-639. PMID: 11122472, DOI: 10.1046/j.1365-2583.2000.00224.x.Peer-Reviewed Original ResearchConceptsInsect speciesCytoplasmic incompatibilityDifferent tissue tropismsSingle WolbachiaDefensin genesAntibacterial genesArthropod speciesAnopheles gambiaeWolbachiaExpression patternsMosquito speciesSpeciesGenesMosquito defensinUbiquitous parasiteHost immune systemImmune systemTissue tropismAntimicrobial peptidesTranscriptionAedes aegyptiAedes albopictusReproductive abnormalitiesDrosophilaParthenogenesis