2023
Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study
Sumner K, Masalovich S, O’Halloran A, Holstein R, Reingold A, Kirley P, Alden N, Herlihy R, Meek J, Yousey-Hindes K, Anderson E, Openo K, Monroe M, Leegwater L, Henderson J, Lynfield R, McMahon M, McMullen C, Angeles K, Spina N, Engesser K, Bennett N, Felsen C, Lung K, Shiltz E, Thomas A, Talbot H, Schaffner W, Swain A, George A, Rolfes M, Reed C, Garg S. Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010–19: a repeated cross-sectional study. The Lancet Microbe 2023, 4: e903-e912. PMID: 37769676, PMCID: PMC10872935, DOI: 10.1016/s2666-5247(23)00187-8.Peer-Reviewed Original ResearchConceptsInfluenza virus typeInfluenza-associated hospitalisationsInfluenza seasonInfluenza B virusICU admissionMechanical ventilationSevere outcomesOdds ratioVirus typeFluSurv-NETECMO useInfluenza vaccineB virusVirus infectionLaboratory-confirmed influenza virus infectionInfluenza Hospitalization Surveillance NetworkInfluenza B virus infectionPopulation-based surveillance systemComplete chart reviewEarly antiviral treatmentHospital-onset casesInfluenza-associated outcomesRepeated cross-sectional studyInfluenza vaccination statusB virus infection
2022
Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons
Black C, O’Halloran A, Hung M, Srivastav A, Lu P, Garg S, Jhung M, Fry A, Jatlaoui T, Davenport E, Burns E, Network I, Network I, Reingold A, Alden N, Yousey-Hindes K, Anderson E, Ryan P, Kim S, McMahon M, Bleecker M, Spina N, Bennett N, Lung K, Sutton M, Schaffner W, Talbot H, Crossland M, Reed C, Holstein R, Ujamaa D, Cummings C. Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons. MMWR Morbidity And Mortality Weekly Report 2022, 71: 1366-1373. PMID: 36302226, PMCID: PMC9620569, DOI: 10.15585/mmwr.mm7143e1.Peer-Reviewed Original ResearchConceptsInfluenza vaccination coverageBehavioral Risk Factor Surveillance SystemVaccination coverageHealth care providersInfluenza seasonInfluenza hospitalizationsInfluenza vaccinationAsian adultsCare providersHispanic adultsLaboratory-confirmed influenza-associated hospitalizationsDisease severityLow influenza vaccination coverageNon-Hispanic Asian adultsPersonal health care providerHealth care access barriersNon-Hispanic white personsRisk Factor Surveillance SystemInfluenza disease severityInfluenza hospitalization ratesPatient vaccination statusInfluenza-associated hospitalizationsPopulation-based surveillanceRoutine medical checkupVaccination coverage dataCOVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022
Havers F, Pham H, Taylor C, Whitaker M, Patel K, Anglin O, Kambhampati A, Milucky J, Zell E, Moline H, Chai S, Kirley P, Alden N, Armistead I, Yousey-Hindes K, Meek J, Openo K, Anderson E, Reeg L, Kohrman A, Lynfield R, Como-Sabetti K, Davis E, Cline C, Muse A, Barney G, Bushey S, Felsen C, Billing L, Shiltz E, Sutton M, Abdullah N, Talbot H, Schaffner W, Hill M, George A, Hall A, Bialek S, Murthy N, Murthy B, McMorrow M. COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022. JAMA Internal Medicine 2022, 182: 1071-1081. PMID: 36074486, PMCID: PMC9459904, DOI: 10.1001/jamainternmed.2022.4299.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCOVID-19COVID-19 VaccinesCross-Sectional StudiesHospitalizationHumansInfluenza VaccinesSARS-CoV-2ConceptsCOVID-19-associated hospitalizationUnderlying medical conditionsHospitalization ratesUnvaccinated personsVaccinated personsBooster doseMedical conditionsLaboratory-confirmed COVID-19-associated hospitalizationsLaboratory-confirmed SARS-CoV-2 infectionLong-term care facility residentsPositive SARS-CoV-2 test resultCOVID-19 Associated HospitalizationsDetailed medical record reviewImmunization information system dataSARS-CoV-2 test resultsCOVID-19-Associated Hospitalization Surveillance NetworkSARS-CoV-2 infectionCOVID-19Patients 18 yearsMedical record reviewCare facility residentsVaccination coverage dataAdults 18 yearsCross-sectional studyPublic health efforts
2020
Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults : A Cross-sectional Study.
Chow EJ, Rolfes MA, O'Halloran A, Anderson EJ, Bennett NM, Billing L, Chai S, Dufort E, Herlihy R, Kim S, Lynfield R, McMullen C, Monroe ML, Schaffner W, Spencer M, Talbot HK, Thomas A, Yousey-Hindes K, Reed C, Garg S. Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults : A Cross-sectional Study. Annals Of Internal Medicine 2020, 173: 605-613. PMID: 32833488, PMCID: PMC8097760, DOI: 10.7326/m20-1509.Peer-Reviewed Original ResearchConceptsAcute ischemic heart diseaseAcute heart failureAcute cardiovascular eventsLaboratory-confirmed influenzaCardiovascular eventsCross-sectional studyInfluenza vaccinationDischarge codesInfluenza testingChronic conditionsTobacco useInfluenza Hospitalization Surveillance NetworkInfluenza antiviral medicationsMedical record abstractionIschemic heart diseasePopulation-based studyAnnual influenza epidemicsLogistic regression modelsCommon such eventsRace/ethnicityPractitioner ordersHospitalized adultsAntiviral medicationsHeart failureInfluenza season
2019
Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season
Rolfes MA, Flannery B, Chung JR, O’Halloran A, Garg S, Belongia EA, Gaglani M, Zimmerman RK, Jackson ML, Monto AS, Alden NB, Anderson E, Bennett NM, Billing L, Eckel S, Kirley PD, Lynfield R, Monroe ML, Spencer M, Spina N, Talbot HK, Thomas A, Torres SM, Yousey-Hindes K, Singleton JA, Patel M, Reed C, Fry AM, McLean H, King J, Nowalk M, Balasubramani G, Bear T, Hickey R, Williams J, Reis E, Moehling K, Eng H, Jackson L, Smith M, Raiyani C, Clipper L, Murthy K, Chen W, Reis M, Petrie J, Malosh R, McSpadden E, Segaloff H, Cheng C, Truscon R, Johnson E, Lamerato L, Rosenblum B, Ford S, Johnson M, Raviotta J, Sax T, Steele J, Susick M, Chabra R, Garofolo E, Iozzi P, Kevish B, Middleton D, Urbanski L, Ponder T, Crumbaker T, Iosefo I, Sleeth P, Gandy V, Bounds K, Kylberg M, Rao A, Fader R, Walker K, Volz M, Ray J, Price D, Thomas J, Wehbe-Janek H, Beeram M, Boyd J, Walkowiak J, Probe R, Couchman G, Motakef S, Arroliga A, Kaniclides A, Bouldin E, Baker C, Berke K, Smith M, Rajesh N, Alleman E, Bauer S, Groesbeck M, Brundidge K, Hafeez N, Jackson J, Anastasia I, Kadoo G, Petnic S, Ryan A, Maslar A, Meek J, Chen R, Stephens S, Thomas S, Segler S, Openo K, Fawcett E, Farley M, Martin A, Ryan P, Sunkel R, Lutich T, Perlmutter R, Grace B, Blood T, Zerrlaut C, McMahon M, Strain A, Christensen J, Angeles K, Butler L, Khanlian S, Mansmann R, McMullen C, Pradhan E, Manzi K, Felsen C, Gaitan M, Long K, Fisher N, Hawley E, O’Shaughnessy R, Scott M, Crawford C, Schaffner W, Markus T, Leib K, Dyer K, Santibanez T, Zhai Y, Lu P, Srivastav A, Hung M. Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season. Clinical Infectious Diseases 2019, 69: 1845-1853. PMID: 30715278, PMCID: PMC7188082, DOI: 10.1093/cid/ciz075.Peer-Reviewed Original ResearchConceptsInfluenza-associated illnessVaccine effectivenessInfluenza vaccinationInfluenza seasonMedical visitsCurrent influenza vaccinationInfluenza-associated outcomesInfluenza vaccine coverageInfluenza vaccine effectivenessLaboratory-confirmed influenzaTest-negative designInfluenza virus infectionAge-specific estimatesInfluenza B.Vaccine coverageDisease burdenVirus infectionSubstantial burdenAmbulatory settingVaccinationHospitalizationImproved vaccinesInfluenzaIllnessVisits
2018
Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011–2015
Collins JP, Campbell AP, Openo K, Farley MM, Cummings CN, Kirley PD, Herlihy R, Yousey-Hindes K, Monroe ML, Ladisky M, Lynfield R, Baumbach J, Spina N, Bennett N, Billing L, Thomas A, Schaffner W, Price A, Garg S, Anderson EJ. Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011–2015. Journal Of The Pediatric Infectious Diseases Society 2018, 8: 539-549. PMID: 30358877, DOI: 10.1093/jpids/piy101.Peer-Reviewed Original ResearchConceptsSolid organ transplantationImmunocompromised childrenClinical featuresImmunosuppressive therapyIntensive careOrgan transplantationInfluenza Hospitalization Surveillance NetworkHuman immunodeficiency virus/Community-acquired influenzaEarly antiviral treatmentLonger hospitalization durationDuration of hospitalizationIntensive care admissionAntiviral useCare admissionHospital deathHospitalization durationInfluenza vaccinationAntiviral treatmentInfluenza seasonInfluenza severityPrimary outcomeImmunodeficiency syndromeMultivariable analysisImmunoglobulin deficiency
2017
Influenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza
Arriola C, Garg S, Anderson EJ, Ryan PA, George A, Zansky SM, Bennett N, Reingold A, Bargsten M, Miller L, Yousey-Hindes K, Tatham L, Bohm SR, Lynfield R, Thomas A, Lindegren ML, Schaffner W, Fry AM, Chaves SS. Influenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza. Clinical Infectious Diseases 2017, 65: 1289-1297. PMID: 28525597, PMCID: PMC5718038, DOI: 10.1093/cid/cix468.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaInfluenza vaccinationDisease severityInfluenza seasonIntensive care unit admissionCare unit admissionMultivariable logistic regressionProbability of vaccinationCommunity-dwelling adultsHospital LOSICU LOSUnvaccinated patientsHospital deathICU admissionICU lengthUnit admissionAntiviral treatmentIllness onsetAdverse outcomesOutcome measuresVaccine virusAge strataVaccinationLogistic regressionPropensity score
2014
Impact of requiring influenza vaccination for children in licensed child care or preschool programs--Connecticut, 2012-13 influenza season.
Hadler JL, Yousey-Hindes K, Kudish K, Kennedy ED, Sacco V, Cartter ML. Impact of requiring influenza vaccination for children in licensed child care or preschool programs--Connecticut, 2012-13 influenza season. MMWR Morbidity And Mortality Weekly Report 2014, 63: 181-5. PMID: 24598593, PMCID: PMC4584725.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalization ratesEmerging Infections ProgramInfluenza seasonHospitalization ratesVaccination ratesInfluenza transmissionSevere influenza-related illnessInfluenza-related illnessInfluenza-associated hospitalizationsLicensed child care programsOverall population rateGreater percentage decreaseCare admissionInfluenza vaccinationInfluenza vaccineSerious morbiditySusceptible childrenVaccination levelsInfections ProgramVaccination dataCare settingsEIP sitesCare programConnecticut childrenSurveillance sites