2024
Trends in COVID‐19–Attributable Hospitalizations Among Adults With Laboratory‐Confirmed SARS‐CoV‐2—COVID‐NET, June 2020 to September 2023
Taylor C, Whitaker M, Patton M, Melgar M, Kirley P, Kawasaki B, Yousey‐Hindes K, Openo K, Ryan P, Kim S, Como‐Sabetti K, Solhtalab D, Barney G, Tesini B, Moran N, Sutton M, Talbot H, Olsen K, Havers F. Trends in COVID‐19–Attributable Hospitalizations Among Adults With Laboratory‐Confirmed SARS‐CoV‐2—COVID‐NET, June 2020 to September 2023. Influenza And Other Respiratory Viruses 2024, 18: e70021. PMID: 39496579, PMCID: PMC11534501, DOI: 10.1111/irv.70021.Peer-Reviewed Original Research
2023
COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023
Taylor C, Patel K, Patton M, Reingold A, Kawasaki B, Meek J, Openo K, Ryan P, Falkowski A, Bye E, Plymesser K, Spina N, Tesini B, Moran N, Sutton M, Talbot H, George A, Havers F, Team C, Team C, Kirley P, Armistead I, Yousey-Hindes K, Oosmanally N, Monroe M, Henderson J, D’Heilly P, Hancock E, Barney G, Bushey S, Billing L, Abdullah N, Schaffner W, Mendez E. COVID-19–Associated Hospitalizations Among U.S. Adults Aged ≥65 Years — COVID-NET, 13 States, January–August 2023. MMWR Morbidity And Mortality Weekly Report 2023, 72: 1089-1094. PMID: 37796744, PMCID: PMC10564325, DOI: 10.15585/mmwr.mm7240a3.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalization ratesHospitalization ratesAge groupsIntensive care unit admissionMultiple underlying conditionsSevere COVID-19 diseasePromote early treatmentPositive SARS-CoV-2 testSARS-CoV-2 infectionPrevent SARS-CoV-2 infectionYounger age groupsClinical characteristicsUnit admissionUnderlying conditionEarly treatmentSARS-CoV-2 testingIncreased riskSevere COVID-19-associated outcomesSevere outcomesCOVID-19 hospitalizationElevated riskCOVID-19 diseaseBivalent vaccine
2022
Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons
Black C, O’Halloran A, Hung M, Srivastav A, Lu P, Garg S, Jhung M, Fry A, Jatlaoui T, Davenport E, Burns E, Network I, Network I, Reingold A, Alden N, Yousey-Hindes K, Anderson E, Ryan P, Kim S, McMahon M, Bleecker M, Spina N, Bennett N, Lung K, Sutton M, Schaffner W, Talbot H, Crossland M, Reed C, Holstein R, Ujamaa D, Cummings C. Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons. MMWR Morbidity And Mortality Weekly Report 2022, 71: 1366-1373. PMID: 36302226, PMCID: PMC9620569, DOI: 10.15585/mmwr.mm7143e1.Peer-Reviewed Original ResearchConceptsInfluenza vaccination coverageBehavioral Risk Factor Surveillance SystemVaccination coverageHealth care providersInfluenza seasonInfluenza hospitalizationsInfluenza vaccinationAsian adultsCare providersHispanic adultsLaboratory-confirmed influenza-associated hospitalizationsDisease severityLow influenza vaccination coverageNon-Hispanic Asian adultsPersonal health care providerHealth care access barriersNon-Hispanic white personsRisk Factor Surveillance SystemInfluenza disease severityInfluenza hospitalization ratesPatient vaccination statusInfluenza-associated hospitalizationsPopulation-based surveillanceRoutine medical checkupVaccination coverage dataDrug use and severe outcomes among adults hospitalized with influenza, 2016–2019
Parisi C, Yousey‐Hindes K, Holstein R, O'Halloran A, Kirley P, Alden N, Anderson E, Kim S, McMahon M, Khanlian S, Spina N, Gaitan M, Shiltz E, Thomas A, Schaffner W, Talbot K, Crossland M, Cook R, Garg S, Meek J, Hadler J. Drug use and severe outcomes among adults hospitalized with influenza, 2016–2019. Influenza And Other Respiratory Viruses 2022, 17: e13052. PMID: 36300969, PMCID: PMC9835414, DOI: 10.1111/irv.13052.Peer-Reviewed Original ResearchConceptsSevere outcomesDrug useICU admissionMechanical ventilationInfluenza Hospitalization Surveillance NetworkInfluenza-associated outcomesSevere influenza outcomesPersistent public health problemChronic liver diseaseChronic lung diseasePublic health problemNon-Hispanic blacksLogistic regression modelsHispanics/LatinosSmoke tobaccoInfluenza vaccinationOpioid useImmunosuppressive conditionsInfluenza seasonSevere morbidityInfluenza infectionInfluenza outcomesLiver diseaseLung diseaseChronic conditionsCOVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022
Havers F, Pham H, Taylor C, Whitaker M, Patel K, Anglin O, Kambhampati A, Milucky J, Zell E, Moline H, Chai S, Kirley P, Alden N, Armistead I, Yousey-Hindes K, Meek J, Openo K, Anderson E, Reeg L, Kohrman A, Lynfield R, Como-Sabetti K, Davis E, Cline C, Muse A, Barney G, Bushey S, Felsen C, Billing L, Shiltz E, Sutton M, Abdullah N, Talbot H, Schaffner W, Hill M, George A, Hall A, Bialek S, Murthy N, Murthy B, McMorrow M. COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022. JAMA Internal Medicine 2022, 182: 1071-1081. PMID: 36074486, PMCID: PMC9459904, DOI: 10.1001/jamainternmed.2022.4299.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationUnderlying medical conditionsHospitalization ratesUnvaccinated personsVaccinated personsBooster doseMedical conditionsLaboratory-confirmed COVID-19-associated hospitalizationsLaboratory-confirmed SARS-CoV-2 infectionLong-term care facility residentsPositive SARS-CoV-2 test resultCOVID-19 Associated HospitalizationsDetailed medical record reviewImmunization information system dataSARS-CoV-2 test resultsCOVID-19-Associated Hospitalization Surveillance NetworkSARS-CoV-2 infectionCOVID-19Patients 18 yearsMedical record reviewCare facility residentsVaccination coverage dataAdults 18 yearsCross-sectional studyPublic health efforts
2021
Characteristics and Outcomes of Hospitalized Pregnant Women With Influenza, 2010 to 2019 : A Repeated Cross-Sectional Study.
Holstein R, Dawood FS, O'Halloran A, Cummings C, Ujamaa D, Daily Kirley P, Yousey-Hindes K, Fawcett E, Monroe ML, Kim S, Lynfield R, McMullen C, Muse A, Bennett NM, Billing LM, Sutton M, Thomas A, Talbot HK, Schaffner W, Risk I, Reed C, Garg S. Characteristics and Outcomes of Hospitalized Pregnant Women With Influenza, 2010 to 2019 : A Repeated Cross-Sectional Study. Annals Of Internal Medicine 2021, 175: 149-158. PMID: 34958603, DOI: 10.7326/m21-3668.Peer-Reviewed Original ResearchConceptsInfluenza-associated outcomesPregnant womenCross-sectional studyFetal outcomesHospital dischargeInfluenza seasonMechanical ventilationInfluenza Hospitalization Surveillance NetworkIntensive care unit admissionMedical chart abstractionRepeated cross-sectional studySevere maternal outcomesCare unit admissionLaboratory-confirmed influenzaReproductive-aged womenHospitalized pregnant womenInfluenza A H1N1Multivariable logistic regressionHigh-priority target groupUnit admissionHospital deathICU admissionMaternal outcomesChart abstractionClinical characteristicsRacial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021
Acosta AM, Garg S, Pham H, Whitaker M, Anglin O, O’Halloran A, Milucky J, Patel K, Taylor C, Wortham J, Chai SJ, Kirley PD, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Monroe ML, Ryan P, Reeg L, Kohrman A, Lynfield R, Bye E, Torres S, Salazar-Sanchez Y, Muse A, Barney G, Bennett NM, Bushey S, Billing L, Shiltz E, Sutton M, Abdullah N, Talbot HK, Schaffner W, Ortega J, Price A, Fry AM, Hall A, Kim L, Havers FP. Racial and Ethnic Disparities in Rates of COVID-19–Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death in the United States From March 2020 to February 2021. JAMA Network Open 2021, 4: e2130479. PMID: 34673962, PMCID: PMC8531997, DOI: 10.1001/jamanetworkopen.2021.30479.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationIntensive care unit admissionCare unit admissionSevere COVID-19Age-adjusted ratesICU admissionHospital deathUnit admissionWhite personsPacific Islander personsLaboratory-confirmed COVID-19-associated hospitalizationsAlaska NativesCOVID-19Positive SARS-CoV-2 testCOVID-19 Associated HospitalizationsEthnic disparitiesCOVID-19-Associated Hospitalization Surveillance NetworkSARS-CoV-2 testNon-Hispanic white personsIn-Hospital DeathRate ratioCross-sectional studyNon-Hispanic American IndianEthnic minority groupsNon-Hispanic blacksCensus tract socioeconomic indicators and COVID-19-associated hospitalization rates—COVID-NET surveillance areas in 14 states, March 1–April 30, 2020
Wortham JM, Meador SA, Hadler JL, Yousey-Hindes K, See I, Whitaker M, O’Halloran A, Milucky J, Chai SJ, Reingold A, Alden NB, Kawasaki B, Anderson EJ, Openo KP, Weigel A, Monroe ML, Ryan PA, Kim S, Reeg L, Lynfield R, McMahon M, Sosin DM, Eisenberg N, Rowe A, Barney G, Bennett NM, Bushey S, Billing LM, Shiltz J, Sutton M, West N, Talbot HK, Schaffner W, McCaffrey K, Spencer M, Kambhampati AK, Anglin O, Piasecki AM, Holstein R, Hall AJ, Fry AM, Garg S, Kim L. Census tract socioeconomic indicators and COVID-19-associated hospitalization rates—COVID-NET surveillance areas in 14 states, March 1–April 30, 2020. PLOS ONE 2021, 16: e0257622. PMID: 34559838, PMCID: PMC8462704, DOI: 10.1371/journal.pone.0257622.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationHigh-poverty census tractsHospitalization ratesFederal poverty levelNon-Hispanic black personsNon-Hispanic white personsHispanic personsAge-adjusted hospitalization ratesPopulation-based surveillanceLow-poverty census tractsCensus tractsPublic health practiceClinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020
Garg S, Patel K, Pham H, Whitaker M, O'Halloran A, Milucky J, Anglin O, Kirley PD, Reingold A, Kawasaki B, Herlihy R, Yousey-Hindes K, Maslar A, Anderson EJ, Openo KP, Weigel A, Teno K, Ryan PA, Monroe ML, Reeg L, Kim S, Como-Sabetti K, Bye E, Davis S, Eisenberg N, Muse A, Barney G, Bennett NM, Felsen CB, Billing L, Shiltz J, Sutton M, Abdullah N, Talbot HK, Schaffner W, Hill M, Chatelain R, Wortham J, Taylor C, Hall A, Fry AM, Kim L, Havers FP. Clinical Trends Among U.S. Adults Hospitalized With COVID-19, March to December 2020. Annals Of Internal Medicine 2021, 174: m21-1991. PMID: 34370517, PMCID: PMC8381761, DOI: 10.7326/m21-1991.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine MonophosphateAdolescentAdrenal Cortex HormonesAdultAge DistributionAgedAlanineAntiviral AgentsCOVID-19Critical CareCross-Sectional StudiesFemaleHospitalizationHumansIntensive Care UnitsLength of StayMaleMiddle AgedPandemicsRespiration, ArtificialSARS-CoV-2United StatesVasoconstrictor AgentsYoung AdultConceptsICU admissionClinical trendsMechanical ventilationCOVID-19COVID-19-associated hospitalizationIntensive care unit admissionLaboratory-confirmed COVID-19U.S. adultsNon-Hispanic black personsCare unit admissionHospital death rateNoninvasive respiratory supportUse of remdesivirPercentage of interventionsCross-sectional studyCOVID-19 vaccineNon-Hispanic whitesSystemic corticosteroidsUnit admissionVasopressor useHospitalized adultsRespiratory supportCase patientsMedian ageSubstantial morbidityRates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019
O’Halloran A, Holstein R, Cummings C, Kirley P, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan P, Kim S, Lynfield R, McMullen C, Bennett NM, Spina N, Billing LM, Sutton M, Schaffner W, Talbot HK, Price A, Fry AM, Reed C, Garg S. Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019. JAMA Network Open 2021, 4: e2121880. PMID: 34427679, PMCID: PMC8385599, DOI: 10.1001/jamanetworkopen.2021.21880.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalizationsIntensive care unit admissionCare unit admissionCross-sectional studyHospitalization ratesPacific Islander childrenHospital deathICU admissionUnit admissionInfluenza seasonMAIN OUTCOMELaboratory-confirmed influenza-associated hospitalizationsAge groupsAge-adjusted hospitalization ratesHospital death rateICU admission rateInfluenza-associated diseaseInfluenza-associated outcomesIn-Hospital DeathSevere influenza diseaseHispanic childrenPopulation-based surveillanceWhite personsAlaska NativesAge-stratified rates
2020
Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System
Ko JY, Danielson ML, Town M, Derado G, Greenlund KJ, Kirley PD, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan PA, Kim S, Lynfield R, Torres SM, Barney GR, Bennett NM, Sutton M, Talbot HK, Hill M, Hall AJ, Fry AM, Garg S, Kim L, Whitaker M, O’Halloran A, Holstein R, Garvin W, Chai S, Kawasaki B, Meek J, Openo K, Monroe M, Henderson J, Como-Sabetti K, Davis S, Spina N, Felsen C, West N, Schaffner W, George A. Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System. Clinical Infectious Diseases 2020, 72: e695-e703. PMID: 32945846, PMCID: PMC7543371, DOI: 10.1093/cid/ciaa1419.Peer-Reviewed Original ResearchConceptsCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalizationChronic kidney diseaseHospitalization ratesRace/ethnicitySevere obesityKidney diseaseRisk factorsMedical conditionsLaboratory-confirmed COVID-19Chronic obstructive pulmonary diseaseBehavioral Risk Factor Surveillance SystemRisk Factor Surveillance SystemHigher hospitalization riskRace/ethnicity strataHistory of strokeObstructive pulmonary diseaseUnderlying medical conditionsCoronary artery diseaseHigher hospitalization ratesCommunity-dwelling adultsCoronavirus disease 2019Surveillance networkPoisson regression modelsSurveillance systemRisk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET)
Kim L, Garg S, O’Halloran A, Whitaker M, Pham H, Anderson EJ, Armistead I, Bennett NM, Billing L, Como-Sabetti K, Hill M, Kim S, Monroe ML, Muse A, Reingold AL, Schaffner W, Sutton M, Talbot HK, Torres SM, Yousey-Hindes K, Holstein R, Cummings C, Brammer L, Hall AJ, Fry AM, Langley GE. Risk Factors for Intensive Care Unit Admission and In-hospital Mortality Among Hospitalized Adults Identified through the US Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET). Clinical Infectious Diseases 2020, 72: e206-e214. PMID: 32674114, PMCID: PMC7454425, DOI: 10.1093/cid/ciaa1012.Peer-Reviewed Original ResearchConceptsIntensive care unit admissionCare unit admissionHospital mortalityICU admissionUnit admissionMale sexRisk factorsAge 50Independent factorsCOVID-19-related complicationsLaboratory-confirmed COVID-19Surveillance networkCoronavirus disease 2019 (COVID-19) casesInvasive mechanical ventilationIn-Hospital MortalityChronic lung diseaseAcute care hospitalsCoronavirus disease 2019COVID-19Rigorous hand hygieneRenal diseaseMechanical ventilationMultivariable analysisLung diseaseSevere outcomesRespiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults
Chow EJ, Rolfes MA, O’Halloran A, Alden NB, Anderson EJ, Bennett NM, Billing L, Dufort E, Kirley PD, George A, Irizarry L, Kim S, Lynfield R, Ryan P, Schaffner W, Talbot HK, Thomas A, Yousey-Hindes K, Reed C, Garg S. Respiratory and Nonrespiratory Diagnoses Associated With Influenza in Hospitalized Adults. JAMA Network Open 2020, 3: e201323. PMID: 32196103, PMCID: PMC7084169, DOI: 10.1001/jamanetworkopen.2020.1323.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaRespiratory diagnosesInfluenza seasonAcute diagnosisInfluenza Hospitalization Surveillance NetworkPositive influenza test resultsRevision discharge diagnosis codesSeasonal influenza virus infectionCommon acute diagnosesEarly antiviral treatmentAcute kidney injuryMedical record abstractionPatient demographic characteristicsDischarge diagnosis codesBurden of infectionInfluenza virus infectionInfluenza test resultsCross-sectional studyTranscription-polymerase chain reactionIndirect fluorescent stainingInternational Statistical ClassificationSurveillance networkRelated Health ProblemsFluSurv-NETHospital outcomesSpatial and temporal clustering of patients hospitalized with laboratory-confirmed influenza in the United States
Sloan C, Chandrasekhar R, Mitchel E, Ndi D, Miller L, Thomas A, Bennett NM, Chai S, Spencer M, Eckel S, Spina N, Monroe M, Anderson EJ, Lynfield R, Yousey-Hindes K, Bargsten M, Zansky S, Lung K, Schroeder M, N Cummings C, Garg S, Schaffner W, Lindegren ML. Spatial and temporal clustering of patients hospitalized with laboratory-confirmed influenza in the United States. Epidemics 2020, 31: 100387. PMID: 32371346, DOI: 10.1016/j.epidem.2020.100387.Peer-Reviewed Original ResearchConceptsRelative riskHospitalization burdenInfluenza Hospitalization Surveillance NetworkSocioeconomic factorsLaboratory-confirmed influenzaTiming of influenzaScan statistics analysisInfluenza seasonDisease burdenEpidemic timingSurveillance dataInfluenzaPandemic yearSpatial scan statisticSurveillance networkBurdenLocal socioeconomic factorsUnited StatesEpidemic intensityYearsPhase synchronyNational patternsPatientsSocioeconomicsFactors
2019
Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season
Rolfes MA, Flannery B, Chung JR, O’Halloran A, Garg S, Belongia EA, Gaglani M, Zimmerman RK, Jackson ML, Monto AS, Alden NB, Anderson E, Bennett NM, Billing L, Eckel S, Kirley PD, Lynfield R, Monroe ML, Spencer M, Spina N, Talbot HK, Thomas A, Torres SM, Yousey-Hindes K, Singleton JA, Patel M, Reed C, Fry AM, McLean H, King J, Nowalk M, Balasubramani G, Bear T, Hickey R, Williams J, Reis E, Moehling K, Eng H, Jackson L, Smith M, Raiyani C, Clipper L, Murthy K, Chen W, Reis M, Petrie J, Malosh R, McSpadden E, Segaloff H, Cheng C, Truscon R, Johnson E, Lamerato L, Rosenblum B, Ford S, Johnson M, Raviotta J, Sax T, Steele J, Susick M, Chabra R, Garofolo E, Iozzi P, Kevish B, Middleton D, Urbanski L, Ponder T, Crumbaker T, Iosefo I, Sleeth P, Gandy V, Bounds K, Kylberg M, Rao A, Fader R, Walker K, Volz M, Ray J, Price D, Thomas J, Wehbe-Janek H, Beeram M, Boyd J, Walkowiak J, Probe R, Couchman G, Motakef S, Arroliga A, Kaniclides A, Bouldin E, Baker C, Berke K, Smith M, Rajesh N, Alleman E, Bauer S, Groesbeck M, Brundidge K, Hafeez N, Jackson J, Anastasia I, Kadoo G, Petnic S, Ryan A, Maslar A, Meek J, Chen R, Stephens S, Thomas S, Segler S, Openo K, Fawcett E, Farley M, Martin A, Ryan P, Sunkel R, Lutich T, Perlmutter R, Grace B, Blood T, Zerrlaut C, McMahon M, Strain A, Christensen J, Angeles K, Butler L, Khanlian S, Mansmann R, McMullen C, Pradhan E, Manzi K, Felsen C, Gaitan M, Long K, Fisher N, Hawley E, O’Shaughnessy R, Scott M, Crawford C, Schaffner W, Markus T, Leib K, Dyer K, Santibanez T, Zhai Y, Lu P, Srivastav A, Hung M. Effects of Influenza Vaccination in the United States During the 2017–2018 Influenza Season. Clinical Infectious Diseases 2019, 69: 1845-1853. PMID: 30715278, PMCID: PMC7188082, DOI: 10.1093/cid/ciz075.Peer-Reviewed Original ResearchConceptsInfluenza-associated illnessVaccine effectivenessInfluenza vaccinationInfluenza seasonMedical visitsCurrent influenza vaccinationInfluenza-associated outcomesInfluenza vaccine coverageInfluenza vaccine effectivenessLaboratory-confirmed influenzaTest-negative designInfluenza virus infectionAge-specific estimatesInfluenza B.Vaccine coverageDisease burdenVirus infectionSubstantial burdenAmbulatory settingVaccinationHospitalizationImproved vaccinesInfluenzaIllnessVisits
2017
Social determinants of influenza hospitalization in the United States
Chandrasekhar R, Sloan C, Mitchel E, Ndi D, Alden N, Thomas A, Bennett NM, Kirley PD, Hill M, Anderson EJ, Lynfield R, Yousey‐Hindes K, Bargsten M, Zansky SM, Lung K, Schroeder M, Monroe M, Eckel S, Markus TM, Cummings CN, Garg S, Schaffner W, Lindegren ML. Social determinants of influenza hospitalization in the United States. Influenza And Other Respiratory Viruses 2017, 11: 479-488. PMID: 28872776, PMCID: PMC5720587, DOI: 10.1111/irv.12483.Peer-Reviewed Original ResearchConceptsAdjusted odds ratioInfluenza hospitalizationsLaboratory-confirmed influenza-associated hospitalizationsHigher adjusted odds ratioPopulation-based surveillance systemInfluenza-associated hospitalizationsInfluenza seasonSubstantial morbidityVs 5Odds ratioHospitalizationHousehold crowdingSocial determinantsTractIndividual factorsMultilevel regression modelsSocioeconomic determinantsAfrican AmericansSurveillance systemRegression modelsUnited StatesHispanicsIndividual-level determinantsDeterminantsMorbidityImpact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012
Kline K, Hadler JL, Yousey‐Hindes K, Niccolai L, Kirley PD, Miller L, Anderson EJ, Monroe ML, Bohm SR, Lynfield R, Bargsten M, Zansky SM, Lung K, Thomas AR, Brady D, Schaffner W, Reed G, Garg S. Impact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012. Influenza And Other Respiratory Viruses 2017, 11: 404-411. PMID: 28703414, PMCID: PMC5596517, DOI: 10.1111/irv.12465.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInfluenza-associated hospitalizationsMale incidence rate ratiosPregnant womenLaboratory-confirmed influenza-associated hospitalizationsFemale incidence rate ratiosLaboratory-confirmed influenza casesLaboratory-confirmed influenzaLikelihood of vaccinationPopulation-based surveillanceNon-pregnant womenImpact of pregnancyNon-pregnant counterpartsCensus tract-level povertyObserved sex disparityGroup of womenTract-level povertyRace/ethnicityPregnant adult femalesFluSurv-NETHospitalized femalesInfluenza seasonAdult casesVaccination priorityVaccination ratesInfluenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza
Arriola C, Garg S, Anderson EJ, Ryan PA, George A, Zansky SM, Bennett N, Reingold A, Bargsten M, Miller L, Yousey-Hindes K, Tatham L, Bohm SR, Lynfield R, Thomas A, Lindegren ML, Schaffner W, Fry AM, Chaves SS. Influenza Vaccination Modifies Disease Severity Among Community-dwelling Adults Hospitalized With Influenza. Clinical Infectious Diseases 2017, 65: 1289-1297. PMID: 28525597, PMCID: PMC5718038, DOI: 10.1093/cid/cix468.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaInfluenza vaccinationDisease severityInfluenza seasonIntensive care unit admissionCare unit admissionMultivariable logistic regressionProbability of vaccinationCommunity-dwelling adultsHospital LOSICU LOSUnvaccinated patientsHospital deathICU admissionICU lengthUnit admissionAntiviral treatmentIllness onsetAdverse outcomesOutcome measuresVaccine virusAge strataVaccinationLogistic regressionPropensity score
2016
Influenza-Related Hospitalizations and Poverty Levels - United States, 2010-2012.
Hadler JL, Yousey-Hindes K, Pérez A, Anderson EJ, Bargsten M, Bohm SR, Hill M, Hogan B, Laidler M, Lindegren ML, Lung KL, Mermel E, Miller L, Morin C, Parker E, Zansky SM, Chaves SS. Influenza-Related Hospitalizations and Poverty Levels - United States, 2010-2012. MMWR Morbidity And Mortality Weekly Report 2016, 65: 101-5. PMID: 26866729, DOI: 10.15585/mmwr.mm6505a1.Peer-Reviewed Original ResearchConceptsInfluenza related hospitalizationsInfluenza-related diseaseInfluenza-related hospitalizationsAge-adjusted incidenceAnnual influenza vaccineLow-poverty census tractsCensus tractsHigh-poverty census tractsFederal poverty levelInfluenza seasonHospitalization incidenceInfluenza vaccineHospitalization dataSevere diseaseCurrent recommendationsVaccination effortsAntiviral agentsVaccination outreachSocioeconomic status measuresStatus measuresSurveillance sitesSurveillance data analysisTractSES dataIncidence
2015
Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials
Baggs J, Yousey-Hindes K, Ashley ED, Meek J, Dumyati G, Cohen J, Wise ME, McDonald LC, Lessa FC. Identification of population at risk for future Clostridium difficile infection following hospital discharge to be targeted for vaccine trials. Vaccine 2015, 33: 6241-6249. PMID: 26450660, PMCID: PMC4702247, DOI: 10.1016/j.vaccine.2015.09.078.Peer-Reviewed Original ResearchConceptsEmerging Infections ProgramHigh-risk groupRisk groupsRisk scoreIndex hospitalizationHospital dischargeDerivation cohortVaccine trialsValidation cohortDifficile infectionCox proportional hazards modelRisk of CDIAcute care hospitalizationIdentification of patientsClostridium difficile infectionHospital discharge dataNumber of hospitalizationsLow-risk groupProportional hazards modelLarge academic centerAdmission diagnosisPrimary outcomeInpatient stayPatient populationPharmacy data