2024
The burden of all-cause mortality following influenza-associated hospitalizations, FluSurv-NET, 2010-2019
O’Halloran A, Millman A, Holstein R, Olsen S, Cummings C, Chai S, Kirley P, Alden N, Yousey-Hindes K, Meek J, Openo K, Fawcett E, Ryan P, Leegwater L, Henderson J, McMahon M, Lynfield R, Angeles K, Bleecker M, McGuire S, Spina N, Tesini B, Gaitan M, Lung K, Shiltz E, Thomas A, Talbott H, Schaffner W, Hill M, Reed C, Garg S. The burden of all-cause mortality following influenza-associated hospitalizations, FluSurv-NET, 2010-2019. Clinical Infectious Diseases 2024, ciae547. PMID: 39495002, DOI: 10.1093/cid/ciae547.Peer-Reviewed Original ResearchInfluenza-associated hospitalizationsInfluenza-associated deathsIn-hospitalInfluenza Hospitalization Surveillance NetworkClinical characteristics of patientsHospital dischargeLaboratory-confirmed influenzaImpact of influenzaCharacteristics of patientsAll-cause mortalityMedical conditionsDied in-hospitalFluSurv-NETInfluenza hospitalizationsPost-discharge outcomesClinical characteristicsDeath certificatesOlder patientsPost-dischargeMedian daysPost-discharge deathsInfluenzaPatientsDays post-dischargeCardiovascular disease
2022
COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022
Havers F, Pham H, Taylor C, Whitaker M, Patel K, Anglin O, Kambhampati A, Milucky J, Zell E, Moline H, Chai S, Kirley P, Alden N, Armistead I, Yousey-Hindes K, Meek J, Openo K, Anderson E, Reeg L, Kohrman A, Lynfield R, Como-Sabetti K, Davis E, Cline C, Muse A, Barney G, Bushey S, Felsen C, Billing L, Shiltz E, Sutton M, Abdullah N, Talbot H, Schaffner W, Hill M, George A, Hall A, Bialek S, Murthy N, Murthy B, McMorrow M. COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022. JAMA Internal Medicine 2022, 182: 1071-1081. PMID: 36074486, PMCID: PMC9459904, DOI: 10.1001/jamainternmed.2022.4299.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationUnderlying medical conditionsHospitalization ratesUnvaccinated personsVaccinated personsBooster doseMedical conditionsLaboratory-confirmed COVID-19-associated hospitalizationsLaboratory-confirmed SARS-CoV-2 infectionLong-term care facility residentsPositive SARS-CoV-2 test resultCOVID-19 Associated HospitalizationsDetailed medical record reviewImmunization information system dataSARS-CoV-2 test resultsCOVID-19-Associated Hospitalization Surveillance NetworkSARS-CoV-2 infectionCOVID-19Patients 18 yearsMedical record reviewCare facility residentsVaccination coverage dataAdults 18 yearsCross-sectional studyPublic health efforts
2021
Influenza Antiviral Treatment and Length of Stay
Campbell AP, Tokars JI, Reynolds S, Garg S, Kirley PD, Miller L, Yousey-Hindes K, Anderson EJ, Oni O, Monroe M, Kim S, Lynfield R, Smelser C, Muse AT, Felsen C, Billing LM, Thomas A, Mermel E, Lindegren ML, Schaffner W, Price A, Fry AM. Influenza Antiviral Treatment and Length of Stay. Pediatrics 2021, 148: e2021050417. PMID: 34470815, DOI: 10.1542/peds.2021-050417.Peer-Reviewed Original ResearchConceptsLaboratory-confirmed influenzaAntiviral treatmentMedical conditionsHospitalized patientsIllness onsetHigh-risk medical conditionsInfluenza Hospitalization Surveillance NetworkKaplan-Meier survival analysisEarly antiviral treatmentEmpiric antiviral treatmentInfluenza antiviral treatmentLength of stayHospital lengthICU cohortMedian LOSSymptom onsetShorter hospitalizationPrevention recommendationsTime-dependent variablesCox modelAntiviral agentsSurvival analysisCohortDisease controlInfluenza
2020
Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System
Ko JY, Danielson ML, Town M, Derado G, Greenlund KJ, Kirley PD, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan PA, Kim S, Lynfield R, Torres SM, Barney GR, Bennett NM, Sutton M, Talbot HK, Hill M, Hall AJ, Fry AM, Garg S, Kim L, Whitaker M, O’Halloran A, Holstein R, Garvin W, Chai S, Kawasaki B, Meek J, Openo K, Monroe M, Henderson J, Como-Sabetti K, Davis S, Spina N, Felsen C, West N, Schaffner W, George A. Risk Factors for Coronavirus Disease 2019 (COVID-19)–Associated Hospitalization: COVID-19–Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System. Clinical Infectious Diseases 2020, 72: e695-e703. PMID: 32945846, PMCID: PMC7543371, DOI: 10.1093/cid/ciaa1419.Peer-Reviewed Original ResearchConceptsCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalizationChronic kidney diseaseHospitalization ratesRace/ethnicitySevere obesityKidney diseaseRisk factorsMedical conditionsLaboratory-confirmed COVID-19Chronic obstructive pulmonary diseaseBehavioral Risk Factor Surveillance SystemRisk Factor Surveillance SystemHigher hospitalization riskRace/ethnicity strataHistory of strokeObstructive pulmonary diseaseUnderlying medical conditionsCoronary artery diseaseHigher hospitalization ratesCommunity-dwelling adultsCoronavirus disease 2019Surveillance networkPoisson regression modelsSurveillance systemHospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020
Garg S, Kim L, Whitaker M, O’Halloran A, Cummings C, Holstein R, Prill M, Chai SJ, Kirley PD, Alden NB, Kawasaki B, Yousey-Hindes K, Niccolai L, Anderson EJ, Openo KP, Weigel A, Monroe ML, Ryan P, Henderson J, Kim S, Como-Sabetti K, Lynfield R, Sosin D, Torres S, Muse A, Bennett NM, Billing L, Sutton M, West N, Schaffner W, Talbot HK, Aquino C, George A, Budd A, Brammer L, Langley G, Hall AJ, Fry A. Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020. MMWR Morbidity And Mortality Weekly Report 2020, 69: 458-464. PMID: 32298251, PMCID: PMC7755063, DOI: 10.15585/mmwr.mm6915e3.Peer-Reviewed Original ResearchCOVID-19-Associated Hospitalization Surveillance NetworkCOVID-19-associated hospitalizationUnderlying medical conditionsHospitalization ratesMedical conditionsOlder adultsLaboratory-confirmed COVID-19-associated hospitalizationsCOVID-19Influenza Hospitalization Surveillance NetworkSerious underlying medical conditionsHealth care system resourcesSurveillance networkCharacteristics of patientsChronic lung diseasePopulation-based surveillanceCoronavirus disease 2019SARS-CoV-2Majority of personsAdult patientsClinical characteristicsDiabetes mellitusClinical spectrumLung diseaseUnderlying conditionCardiovascular disease
2013
Hospital-onset influenza hospitalizations—United States, 2010-2011
Jhung MA, D'Mello T, Pérez A, Aragon D, Bennett NM, Cooper T, Farley MM, Fowler B, Grube SM, Hancock EB, Lynfield R, Morin C, Reingold A, Ryan P, Schaffner W, Sharangpani R, Tengelsen L, Thomas A, Thurston D, Yousey-Hindes K, Zansky S, Finelli L, Chaves SS. Hospital-onset influenza hospitalizations—United States, 2010-2011. American Journal Of Infection Control 2013, 42: 7-11. PMID: 24183534, DOI: 10.1016/j.ajic.2013.06.018.Peer-Reviewed Original ResearchConceptsIntensive care unitChronic medical conditionsCare unitHO casesMedical conditionsLaboratory confirmationInfluenza Hospitalization Surveillance NetworkCommunity-onset casesInfluenza-related hospitalizationsPopulation-based surveillanceInfluenza hospitalizationsHospital admissionInfluenza seasonClinical outcomesMedian lengthInfluenza diagnosisSeasonal influenzaOverall epidemiologyHospitalizationPatientsInfluenzaAdmissionStaySurveillance networkGreater proportionPatients Hospitalized With Laboratory-Confirmed Influenza During the 2010–2011 Influenza Season: Exploring Disease Severity by Virus Type and Subtype
Chaves SS, Aragon D, Bennett N, Cooper T, D'Mello T, Farley M, Fowler B, Hancock E, Kirley PD, Lynfield R, Ryan P, Schaffner W, Sharangpani R, Tengelsen L, Thomas A, Thurston D, Williams J, Yousey-Hindes K, Zansky S, Finelli L. Patients Hospitalized With Laboratory-Confirmed Influenza During the 2010–2011 Influenza Season: Exploring Disease Severity by Virus Type and Subtype. The Journal Of Infectious Diseases 2013, 208: 1305-1314. PMID: 23863950, DOI: 10.1093/infdis/jit316.Peer-Reviewed Original ResearchConceptsVirus type/subtypeAntiviral treatmentTypes/subtypesInfluenza seasonMedical conditionsNeuromuscular disordersOdds of severityPrompt antiviral treatmentChronic lung diseaseChronic metabolic diseaseHospitalized patientsIndependent predictorsMultivariable analysisInfluenza preventionLung diseasePopulation immunityB virusSevere diseaseHealthcare seekingMetabolic diseasesDisease severityVirus typeSurveillance dataVirus strainsPatients