2024
The burden of all-cause mortality following influenza-associated hospitalizations, FluSurv-NET, 2010-2019
O’Halloran A, Millman A, Holstein R, Olsen S, Cummings C, Chai S, Kirley P, Alden N, Yousey-Hindes K, Meek J, Openo K, Fawcett E, Ryan P, Leegwater L, Henderson J, McMahon M, Lynfield R, Angeles K, Bleecker M, McGuire S, Spina N, Tesini B, Gaitan M, Lung K, Shiltz E, Thomas A, Talbott H, Schaffner W, Hill M, Reed C, Garg S. The burden of all-cause mortality following influenza-associated hospitalizations, FluSurv-NET, 2010-2019. Clinical Infectious Diseases 2024, ciae547. PMID: 39495002, DOI: 10.1093/cid/ciae547.Peer-Reviewed Original ResearchInfluenza-associated hospitalizationsInfluenza-associated deathsIn-hospitalInfluenza Hospitalization Surveillance NetworkClinical characteristics of patientsHospital dischargeLaboratory-confirmed influenzaImpact of influenzaCharacteristics of patientsAll-cause mortalityMedical conditionsDied in-hospitalFluSurv-NETInfluenza hospitalizationsPost-discharge outcomesClinical characteristicsDeath certificatesOlder patientsPost-dischargeMedian daysPost-discharge deathsInfluenzaPatientsDays post-dischargeCardiovascular disease
2022
Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons
Black C, O’Halloran A, Hung M, Srivastav A, Lu P, Garg S, Jhung M, Fry A, Jatlaoui T, Davenport E, Burns E, Network I, Network I, Reingold A, Alden N, Yousey-Hindes K, Anderson E, Ryan P, Kim S, McMahon M, Bleecker M, Spina N, Bennett N, Lung K, Sutton M, Schaffner W, Talbot H, Crossland M, Reed C, Holstein R, Ujamaa D, Cummings C. Vital Signs: Influenza Hospitalizations and Vaccination Coverage by Race and Ethnicity—United States, 2009–10 Through 2021–22 Influenza Seasons. MMWR Morbidity And Mortality Weekly Report 2022, 71: 1366-1373. PMID: 36302226, PMCID: PMC9620569, DOI: 10.15585/mmwr.mm7143e1.Peer-Reviewed Original ResearchConceptsInfluenza vaccination coverageBehavioral Risk Factor Surveillance SystemVaccination coverageHealth care providersInfluenza seasonInfluenza hospitalizationsInfluenza vaccinationAsian adultsCare providersHispanic adultsLaboratory-confirmed influenza-associated hospitalizationsDisease severityLow influenza vaccination coverageNon-Hispanic Asian adultsPersonal health care providerHealth care access barriersNon-Hispanic white personsRisk Factor Surveillance SystemInfluenza disease severityInfluenza hospitalization ratesPatient vaccination statusInfluenza-associated hospitalizationsPopulation-based surveillanceRoutine medical checkupVaccination coverage dataComparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021)
Delahoy MJ, Ujamaa D, Taylor CA, Cummings C, Anglin O, Holstein R, Milucky J, O’Halloran A, Patel K, Pham H, Whitaker M, Reingold A, Chai SJ, Alden NB, Kawasaki B, Meek J, Yousey-Hindes K, Anderson EJ, Openo KP, Weigel A, Teno K, Reeg L, Leegwater L, Lynfield R, McMahon M, Ropp S, Rudin D, Muse A, Spina N, Bennett NM, Popham K, Billing LM, Shiltz E, Sutton M, Thomas A, Schaffner W, Talbot HK, Crossland MT, McCaffrey K, Hall AJ, Burns E, McMorrow M, Reed C, Havers FP, Garg S. Comparison of Influenza and Coronavirus Disease 2019–Associated Hospitalizations Among Children Younger Than 18 Years Old in the United States: FluSurv-NET (October–April 2017–2021) and COVID-NET (October 2020–September 2021). Clinical Infectious Diseases 2022, 76: e450-e459. PMID: 35594564, PMCID: PMC9129156, DOI: 10.1093/cid/ciac388.Peer-Reviewed Original ResearchConceptsCOVID-19-associated hospitalizationInfluenza-associated hospitalization ratesHospitalization ratesIntensive care unit admissionPopulation-based surveillance systemCOVID-19COVID-19 pandemicCare unit admissionInfluenza-associated hospitalizationsComparison of influenzaSARS-CoV-2FluSurv-NETICU admissionUnit admissionHospital outcomesInfluenza seasonRespiratory virusesPediatric deathsPediatric hospitalizationsRespiratory illnessSevere outcomesOngoing COVID-19 pandemicAdolescents 12HospitalizationChildren 5Epidemiology, Clinical Characteristics, and Outcomes of Influenza-Associated Hospitalizations in US Children Over 9 Seasons Following the 2009 H1N1 Pandemic
Kamidani S, Garg S, Rolfes MA, Campbell AP, Cummings CN, Haston JC, Openo KP, Fawcett E, Chai SJ, Herlihy R, Yousey-Hindes K, Monroe ML, Kim S, Lynfield R, Smelser C, Muse A, Felsen CB, Billing L, Thomas A, Talbot HK, Schaffner W, Risk I, Anderson EJ. Epidemiology, Clinical Characteristics, and Outcomes of Influenza-Associated Hospitalizations in US Children Over 9 Seasons Following the 2009 H1N1 Pandemic. Clinical Infectious Diseases 2022, 75: 1930-1939. PMID: 35438769, DOI: 10.1093/cid/ciac296.Peer-Reviewed Original ResearchConceptsInfluenza Hospitalization Surveillance NetworkHospital mortality rateMechanical ventilationMortality rateIntensive care unit admissionRecent population-based dataCare unit admissionInfluenza vaccination ratesLaboratory-confirmed influenzaInfluenza-associated hospitalizationsMultivariable logistic regressionPopulation-based dataHospitalization incidence ratesMonths of ageUnit admissionAntiviral treatmentVaccination ratesRisk factorsIncidence rateHigher oddsUS childrenHospitalizationDisease controlLogistic regressionPneumonia
2021
Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019
O’Halloran A, Holstein R, Cummings C, Kirley P, Alden NB, Yousey-Hindes K, Anderson EJ, Ryan P, Kim S, Lynfield R, McMullen C, Bennett NM, Spina N, Billing LM, Sutton M, Schaffner W, Talbot HK, Price A, Fry AM, Reed C, Garg S. Rates of Influenza-Associated Hospitalization, Intensive Care Unit Admission, and In-Hospital Death by Race and Ethnicity in the United States From 2009 to 2019. JAMA Network Open 2021, 4: e2121880. PMID: 34427679, PMCID: PMC8385599, DOI: 10.1001/jamanetworkopen.2021.21880.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalizationsIntensive care unit admissionCare unit admissionCross-sectional studyHospitalization ratesPacific Islander childrenHospital deathICU admissionUnit admissionInfluenza seasonMAIN OUTCOMELaboratory-confirmed influenza-associated hospitalizationsAge groupsAge-adjusted hospitalization ratesHospital death rateICU admission rateInfluenza-associated diseaseInfluenza-associated outcomesIn-Hospital DeathSevere influenza diseaseHispanic childrenPopulation-based surveillanceWhite personsAlaska NativesAge-stratified rates
2018
2494. Influenza B Hospitalizations Are Associated With Mortality in Children, FluSurv-NET, 2011–2017
Garg S, O’Halloran A, Cummings C, Chai S, Alden N, Yousey-Hindes K, Anderson E, Ryan P, Collins J, Smelser C, Blog D, Felsen C, Billing L, Thomas A, Talbot H, Spencer M, Lynfield R, Reed C. 2494. Influenza B Hospitalizations Are Associated With Mortality in Children, FluSurv-NET, 2011–2017. Open Forum Infectious Diseases 2018, 5: s748-s749. PMCID: PMC6255344, DOI: 10.1093/ofid/ofy210.2146.Peer-Reviewed Original ResearchHospital mortalityUnivariate analysisVirus infectionInfluenza Hospitalization Surveillance NetworkInfluenza B virus infectionLaboratory-confirmed influenzaB virus infectionInfluenza-associated hospitalizationsMultivariable logistic regressionInfluenza B virusNon-Hispanic whitesCharacteristics of childrenClinical courseMedian ageMedical chartsMechanical ventilationIllness onsetIntensive careUnadjusted oddsHospitalized childrenB virusIndependent associationSevere outcomesNeurologic diseaseInfluenza type
2017
Social determinants of influenza hospitalization in the United States
Chandrasekhar R, Sloan C, Mitchel E, Ndi D, Alden N, Thomas A, Bennett NM, Kirley PD, Hill M, Anderson EJ, Lynfield R, Yousey‐Hindes K, Bargsten M, Zansky SM, Lung K, Schroeder M, Monroe M, Eckel S, Markus TM, Cummings CN, Garg S, Schaffner W, Lindegren ML. Social determinants of influenza hospitalization in the United States. Influenza And Other Respiratory Viruses 2017, 11: 479-488. PMID: 28872776, PMCID: PMC5720587, DOI: 10.1111/irv.12483.Peer-Reviewed Original ResearchConceptsAdjusted odds ratioInfluenza hospitalizationsLaboratory-confirmed influenza-associated hospitalizationsHigher adjusted odds ratioPopulation-based surveillance systemInfluenza-associated hospitalizationsInfluenza seasonSubstantial morbidityVs 5Odds ratioHospitalizationHousehold crowdingSocial determinantsTractIndividual factorsMultilevel regression modelsSocioeconomic determinantsAfrican AmericansSurveillance systemRegression modelsUnited StatesHispanicsIndividual-level determinantsDeterminantsMorbidityImpact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012
Kline K, Hadler JL, Yousey‐Hindes K, Niccolai L, Kirley PD, Miller L, Anderson EJ, Monroe ML, Bohm SR, Lynfield R, Bargsten M, Zansky SM, Lung K, Thomas AR, Brady D, Schaffner W, Reed G, Garg S. Impact of pregnancy on observed sex disparities among adults hospitalized with laboratory‐confirmed influenza, FluSurv‐NET, 2010‐2012. Influenza And Other Respiratory Viruses 2017, 11: 404-411. PMID: 28703414, PMCID: PMC5596517, DOI: 10.1111/irv.12465.Peer-Reviewed Original ResearchConceptsIncidence rate ratiosInfluenza-associated hospitalizationsMale incidence rate ratiosPregnant womenLaboratory-confirmed influenza-associated hospitalizationsFemale incidence rate ratiosLaboratory-confirmed influenza casesLaboratory-confirmed influenzaLikelihood of vaccinationPopulation-based surveillanceNon-pregnant womenImpact of pregnancyNon-pregnant counterpartsCensus tract-level povertyObserved sex disparityGroup of womenTract-level povertyRace/ethnicityPregnant adult femalesFluSurv-NETHospitalized femalesInfluenza seasonAdult casesVaccination priorityVaccination rates
2014
Impact of requiring influenza vaccination for children in licensed child care or preschool programs--Connecticut, 2012-13 influenza season.
Hadler JL, Yousey-Hindes K, Kudish K, Kennedy ED, Sacco V, Cartter ML. Impact of requiring influenza vaccination for children in licensed child care or preschool programs--Connecticut, 2012-13 influenza season. MMWR Morbidity And Mortality Weekly Report 2014, 63: 181-5. PMID: 24598593, PMCID: PMC4584725.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalization ratesEmerging Infections ProgramInfluenza seasonHospitalization ratesVaccination ratesInfluenza transmissionSevere influenza-related illnessInfluenza-related illnessInfluenza-associated hospitalizationsLicensed child care programsOverall population rateGreater percentage decreaseCare admissionInfluenza vaccinationInfluenza vaccineSerious morbiditySusceptible childrenVaccination levelsInfections ProgramVaccination dataCare settingsEIP sitesCare programConnecticut childrenSurveillance sites
2013
Effect of the 2009 Influenza A(H1N1) Pandemic on Invasive Pneumococcal Pneumonia
Fleming-Dutra KE, Taylor T, Link-Gelles R, Garg S, Jhung MA, Finelli L, Jain S, Shay D, Chaves SS, Baumbach J, Hancock EB, Beall B, Bennett N, Zansky S, Petit S, Yousey-Hindes K, Farley MM, Gershman K, Harrison LH, Ryan P, Lexau C, Lynfield R, Reingold A, Schaffner W, Thomas A, Moore MR. Effect of the 2009 Influenza A(H1N1) Pandemic on Invasive Pneumococcal Pneumonia. The Journal Of Infectious Diseases 2013, 207: 1135-1143. PMID: 23303809, DOI: 10.1093/infdis/jit008.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedChildChild, PreschoolConfidence IntervalsDatabases, FactualFemaleHospitalizationHumansInfluenza A Virus, H1N1 SubtypeInfluenza, HumanMaleMiddle AgedOdds RatioPandemicsPneumonia, PneumococcalPoisson DistributionPopulation SurveillanceRisk FactorsSeasonsSeverity of Illness IndexStreptococcus pneumoniaeUnited StatesYoung Adult
2011
Neighborhood Socioeconomic Status and Influenza Hospitalizations Among Children: New Haven County, Connecticut, 2003–2010
Yousey-Hindes KM, Hadler JL. Neighborhood Socioeconomic Status and Influenza Hospitalizations Among Children: New Haven County, Connecticut, 2003–2010. American Journal Of Public Health 2011, 101: 1785-1789. PMID: 21778498, PMCID: PMC3154248, DOI: 10.2105/ajph.2011.300224.Peer-Reviewed Original ResearchConceptsInfluenza-associated hospitalizationsPublic Health Disparities Geocoding ProjectNew Haven CountySurveillance dataMean annual incidenceIndividual case characteristicsAge 17 yearsNeighborhood socioeconomic statusInfluenza hospitalizationsInfluenza vaccinationInfluenza seasonAnnual incidenceHospitalization incidenceHospitalizationSocioeconomic status measuresStatus measuresSocioeconomic statusSES dataIncidenceSES measuresOngoing monitoringSES variablesChildrenTractCensus tracts