2023
Genomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil
de Oliveira L, de Rezende I, Navarini V, Marchioro S, Torres A, Croda J, Croda M, Gonçalves C, Xavier J, de Castro E, Lima M, Iani F, Adelino T, Aburjaile F, Demarchi L, Taira D, Zardin M, Fonseca V, Giovanetti M, Andrews J, Alcantara L, Simionatto S. Genomic characterization of SARS-CoV-2 from an indigenous reserve in Mato Grosso do Sul, Brazil. Frontiers In Public Health 2023, 11: 1195779. PMID: 37965526, PMCID: PMC10641392, DOI: 10.3389/fpubh.2023.1195779.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 lineagesIntroduction eventsCharacterization of SARS-CoV-2Nanopore sequencing platformSARS-CoV-2 positive samplesMultiple SARS-CoV-2 variantsMultiple introduction eventsPhylogenetic reconstructionPhylogenetic dataGenome sequenceSequencing platformsGenomic characterizationSARS-CoV-2Genomic surveillanceSARS-CoV-2 variantsLineagesMato GrossoMortality rateViral dynamicsIndigenous populationCo-circulationPrevalence of malesMidwestern BrazilPositive samplesIndigenous mobilization
2020
Risk factors for polymyxin-resistant carbapenemase-producing Enterobacteriaceae in critically ill patients: An epidemiological and clinical study
da Silva K, Baker S, Croda J, Nguyen T, Boinett C, Barbosa L, Tetila A, Simionatto S. Risk factors for polymyxin-resistant carbapenemase-producing Enterobacteriaceae in critically ill patients: An epidemiological and clinical study. International Journal Of Antimicrobial Agents 2020, 55: 105882. PMID: 31923570, DOI: 10.1016/j.ijantimicag.2020.105882.Peer-Reviewed Original ResearchConceptsRisk factorsPolymyxin-resistant strainsNeonatal patientsMortality rateNeonatal intensive care unitEnterobacteriaceae strainsOnly risk factorCentral venous cathetersIntensive care unitCase-control studyPotential risk factorsHigh mortality ratePolymyxin-susceptible strainsCarbapenemase-producing EnterobacteriaceaeCarbapenem exposureAdult patientsAminoglycoside useCarbapenem useRenal failureVenous cathetersIll patientsCare unitUnfavourable outcomePolymerase chain reactionUrinary catheter
2018
A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit
da Silva K, Maciel W, Croda J, Cayô R, Ramos A, de Sales R, Kurihara M, Vasconcelos N, Gales A, Simionatto S. A high mortality rate associated with multidrug-resistant Acinetobacter baumannii ST79 and ST25 carrying OXA-23 in a Brazilian intensive care unit. PLOS ONE 2018, 13: e0209367. PMID: 30592758, PMCID: PMC6310363, DOI: 10.1371/journal.pone.0209367.Peer-Reviewed Original ResearchMeSH KeywordsAcinetobacter baumanniiAcinetobacter InfectionsAdultAgedAged, 80 and overAnti-Bacterial AgentsBacterial ProteinsBeta-LactamasesBrazilCase-Control StudiesCross InfectionDrug Resistance, Multiple, BacterialFemaleHospital MortalityHumansIntensive Care UnitsMaleMicrobial Sensitivity TestsMiddle AgedConceptsOXA-23-producing A. baumanniiHigh mortality rateA. baumanniiMortality rateRisk factorsHealthcare-related risk factorsBrazilian intensive care unitsIntensive care unit patientsIntensive care unit settingCarbapenem-resistant Acinetobacter baumanniiISAba1 insertion sequenceA. baumannii infectionsCare unit patientsIntensive care unitBlaOXA-51 geneUse of cephalosporinsCase-control studyBaumannii infectionsUnit patientsCare unitNasogastric tubeTherapeutic optionsUnit settingNosocomial infectionsSuch infections
2017
High mortality rate associated with KPC-producing Enterobacter cloacae in a Brazilian hospital
da Silva K, Varella T, dos Santos Bet G, Carvalhaes C, Correa M, Vasconcelos N, Croda J, Gales A, Simionatto S. High mortality rate associated with KPC-producing Enterobacter cloacae in a Brazilian hospital. American Journal Of Infection Control 2017, 46: 108-110. PMID: 28844375, DOI: 10.1016/j.ajic.2017.07.011.Peer-Reviewed Original Research
2015
Risk Factors for Death from Visceral Leishmaniasis in an Urban Area of Brazil
Druzian A, de Souza A, de Campos D, Croda J, Higa M, Dorval M, Pompilio M, de Oliveira P, Paniago A. Risk Factors for Death from Visceral Leishmaniasis in an Urban Area of Brazil. PLOS Neglected Tropical Diseases 2015, 9: e0003982. PMID: 26274916, PMCID: PMC4537269, DOI: 10.1371/journal.pntd.0003982.Peer-Reviewed Original ResearchConceptsHIV/AIDSVisceral leishmaniasisRisk factorsAdult patientsMortality rateUrban endemic areaProspective cohort studySecondary bacterial infectionHigh mortality rateEndemic urban areaCohort studyEpidemiological profileMean ageUniversity HospitalEndemic areasMultivariate analysisPatientsBacterial infectionsAIDSDeathSignificant increaseHigh rateLeishmaniasisEdemaRelapse