Complement factor H in molecular regulation of angiogenesis
Li J, Wang K, Starodubtseva M, Nadyrov E, Kapron C, Hoh J, Liu J. Complement factor H in molecular regulation of angiogenesis. Medical Review 2024, 4: 452-466. PMID: 39444793, PMCID: PMC11495524, DOI: 10.1515/mr-2023-0048.Peer-Reviewed Original ResearchComplement factor HComplement factor H geneAge-related macular degenerationComplement factor H proteinFactor HComplement activation fragmentsC-reactive proteinAnti-angiogenic effectsEndothelial heparan sulfateChoroidal neovascularizationMacular degenerationRegulation of angiogenesisMolecular regulation of angiogenesisDeficient miceComplement 3aMembrane attack complexComplement 5aPro-angiogenic eventsAngiogenesis-related diseasesCFH expressionPro-angiogenic capacityAlternative pathwayTherapeutic potentialComplement systemBlood vessels