A Novel Scoring Estimator to Screening for Oncogenic Chimeric Transcripts in Cancer Transcriptome Sequencing
Gu J, Lu Y, Liu S, Lu H, Liu C. A Novel Scoring Estimator to Screening for Oncogenic Chimeric Transcripts in Cancer Transcriptome Sequencing. 2016, 1800-1805. DOI: 10.1109/bibm.2016.7822792.Peer-Reviewed Original ResearchChimeric transcriptsClonal evolution theoryTranscriptome sequencing datasetsTranscriptome sequencing dataLarger clonal sizeTranscriptome sequencingGenomic informationSequencing datasetsSequencing dataTranscriptional signatureNeoplastic cellsTranscriptsBreast cancer cell linesCancer cell linesOncogenic potentialChimeric mutationsFusion mutationsAdjacent normal tissuesCell linesNormal tissuesMutationsTMPRSS2-ERGCancer researchClonal sizeCells