2016
The Fast-Evolving phy-2 Gene Modulates Sexual Development in Response to Light in the Model Fungus Neurospora crassa
Wang Z, Li N, Li J, Dunlap JC, Trail F, Townsend JP. The Fast-Evolving phy-2 Gene Modulates Sexual Development in Response to Light in the Model Fungus Neurospora crassa. MBio 2016, 7: 10.1128/mbio.02148-15. PMID: 26956589, PMCID: PMC4810495, DOI: 10.1128/mbio.02148-15.Peer-Reviewed Original ResearchMeSH KeywordsGene Expression Regulation, FungalLightMeiosisNeurospora crassaPhytochromeRecombination, GeneticConceptsModel fungus Neurospora crassaFungus Neurospora crassaSexual reproductionNeurospora crassaPHY-2Plant developmentPlant pathogensBacterial physiologyEnvironmental signalsSexual developmentSexual development-related genesEvolution of phytochromesDestructive plant pathogensDevelopment-related genesFungal growthRed light sensorFunction of phytochromeVariable light conditionsCritical roleFungal biologyPHY-1Asexual growthPhytochrome functionMost speciesPostfire environment
2013
Sex-linked transcriptional divergence in the hermaphrodite fungus Neurospora tetrasperma
Samils N, Gioti A, Karlsson M, Sun Y, Kasuga T, Bastiaans E, Wang Z, Li N, Townsend JP, Johannesson H. Sex-linked transcriptional divergence in the hermaphrodite fungus Neurospora tetrasperma. Proceedings Of The Royal Society B 2013, 280: 20130862. PMID: 23782882, PMCID: PMC3712418, DOI: 10.1098/rspb.2013.0862.Peer-Reviewed Original ResearchConceptsMating typesFilamentous ascomycete Neurospora tetraspermaNeurospora tetraspermaMating-type locusGene expression levelsExpression divergenceTranscriptional divergencePhenotypic divergenceFungal AnaloguesRecombinational suppressionMat ASequence divergenceN. tetraspermaMale developmentDivergent regionsFemale developmentMolecular phenotypesGenesSexual dimorphismMale tissuesExpression levelsDivergencePhenotypeAgar mediumGenome
2006
Population structure and gene evolution in Saccharomyces cerevisiae
Aa E, Townsend JP, Adams RI, Nielsen KM, Taylor JW. Population structure and gene evolution in Saccharomyces cerevisiae. FEMS Yeast Research 2006, 6: 702-715. PMID: 16879422, DOI: 10.1111/j.1567-1364.2006.00059.x.Peer-Reviewed Original ResearchMeSH KeywordsCloning, MolecularEvolution, MolecularPhylogenyRecombination, GeneticSaccharomyces cerevisiaeSelection, GeneticConceptsPopulation genetic variationPopulation structureS. cerevisiaeDistinct population structureSaccharomyces sensu strictoSulfur-based fungicidesSulfite exporterGene evolutionGene treesGene SSU1Historical selectionTranscription factorsHigh polymorphismNatural isolatesProtein productsCerevisiaeSequence analysisSSU1Oak forestsGreater polymorphismSensu strictoWine yeastSequence studiesFZF1Expression levels
2005
Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii
Johannesson H, Townsend JP, Hung CY, Cole GT, Taylor JW. Concerted Evolution in the Repeats of an Immunomodulating Cell Surface Protein, SOWgp, of the Human Pathogenic Fungi Coccidioides immitis and C. posadasii. Genetics 2005, 171: 109-117. PMID: 15965255, PMCID: PMC1456504, DOI: 10.1534/genetics.105.040923.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, FungalCoccidioidesCoccidioidomycosisDNA, FungalEvolution, MolecularGene ConversionGenetic VariationHumansMembrane GlycoproteinsMutationPhylogenyPolymorphism, GeneticRecombination, GeneticRepetitive Sequences, Nucleic AcidSequence Analysis, DNASpecies SpecificityTandem Repeat SequencesConceptsPathogenic fungus Coccidioides immitisConcerted evolutionProtein-coding genesC. posadasiiGenetic distance analysisPoint mutation rateHost-pathogen interactionsCell surface proteinsGenome dynamicsPathogen's benefitMultigene familyUnequal crossingGeographic rangeFungus Coccidioides immitisRepetitive domainEntire geneMutation rateRepetitive arraysSurface proteinsDistance analysisGenesHost immune systemImmune systemImmunodominant proteinsParasitic phase