A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data
Rice DP, Townsend JP. A Test for Selection Employing Quantitative Trait Locus and Mutation Accumulation Data. Genetics 2012, 190: 1533-1545. PMID: 22298701, PMCID: PMC3316662, DOI: 10.1534/genetics.111.137075.Peer-Reviewed Original ResearchConceptsMutation accumulation dataPhenotypic traitsMutational effectsMutation accumulation experimentsPopulation genetics theoryQuantitative trait lociQuantitative phenotypic traitsAccumulation dataHistory of selectionLocus effect sizesEvolutionary biologistsNeutral evolutionGenetic architectureQTL dataStrong selectionTrait lociSelection strengthDistribution of mutationsNatural selectionPhenotypic diversityHistorical selectionMolecular dataQuantitative traitsGenetic theoryQTLAssessing the Probability of Detection of Horizontal Gene Transfer Events in Bacterial Populations
Townsend JP, Bøhn T, Nielsen KM. Assessing the Probability of Detection of Horizontal Gene Transfer Events in Bacterial Populations. Frontiers In Microbiology 2012, 3: 27. PMID: 22363321, PMCID: PMC3282476, DOI: 10.3389/fmicb.2012.00027.Peer-Reviewed Original ResearchHorizontal gene transfer eventsGene transfer eventsHGT eventsBacterial populationsPopulation genetics theoryTransfer eventsPopulation genetic modelingLevels of selectionBacterial generation timesGenetic driftNatural selectionInitial transformantsGenetic theoryExogenous DNAAntibiotic resistance genesGenetic materialResistance genesStructured populationsImmediate offspringBacterial genotypesGeneration timeHGTBacteriaDNAGrowth dynamics