2021
Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum
Hien D, Paré P, Cooper A, Koama B, Guissou E, Yaméogo K, Yerbanga R, Farrell I, Ouédraogo J, Gnankiné O, Ignell R, Cohuet A, Dabiré R, Stevenson P, Lefèvre T. Contrasting effects of the alkaloid ricinine on the capacity of Anopheles gambiae and Anopheles coluzzii to transmit Plasmodium falciparum. Parasites & Vectors 2021, 14: 479. PMID: 34526119, PMCID: PMC8444468, DOI: 10.1186/s13071-021-04992-z.Peer-Reviewed Original ResearchConceptsAnopheles coluzziiAnopheles gambiaeCastor bean Ricinus communisSecondary phytochemicalsKey phenotypic traitsNovel control agentsPlant-derived sugarsAbility of mosquitoesPhenotypic traitsPlasmodium falciparumParasite growth ratePlant sugarsPlant nectarFeeding assaysControl agentsMosquito physiologyGrowth rateAnopheles speciesSensu latoAnopheles gambiae sensu latoColuzziiGambiae sensu latoPutative roleP. falciparum infectionMosquito survival
2019
Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection
Ruiz J, Yerbanga R, Lefèvre T, Ouedraogo J, Corces V, Gómez-Díaz E. Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection. Epigenetics & Chromatin 2019, 12: 5. PMID: 30616642, PMCID: PMC6322293, DOI: 10.1186/s13072-018-0250-9.Peer-Reviewed Original ResearchConceptsTranscription factorsHistone modificationsChromatin changesGenome-wide distribution mapsInfection-responsive genesHuman malaria parasite Plasmodium falciparumPeptide-encoding genesMalaria parasite Plasmodium falciparumHistone modification enrichmentDorsal transcription factorParasite Plasmodium falciparumImmunity gene expressionJAK/STATHuman malaria parasiteAnopheles gambiae mosquitoesEpigenetic basisFunctional annotationMotif analysisChIP-seqPhenotypic traitsRNA-seqRegulatory elementsGenetic manipulationNatural isolatesAnopheles gambiae