2019
Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection
Ruiz J, Yerbanga R, Lefèvre T, Ouedraogo J, Corces V, Gómez-Díaz E. Chromatin changes in Anopheles gambiae induced by Plasmodium falciparum infection. Epigenetics & Chromatin 2019, 12: 5. PMID: 30616642, PMCID: PMC6322293, DOI: 10.1186/s13072-018-0250-9.Peer-Reviewed Original ResearchConceptsTranscription factorsHistone modificationsChromatin changesGenome-wide distribution mapsInfection-responsive genesHuman malaria parasite Plasmodium falciparumPeptide-encoding genesMalaria parasite Plasmodium falciparumHistone modification enrichmentDorsal transcription factorParasite Plasmodium falciparumImmunity gene expressionJAK/STATHuman malaria parasiteAnopheles gambiae mosquitoesEpigenetic basisFunctional annotationMotif analysisChIP-seqPhenotypic traitsRNA-seqRegulatory elementsGenetic manipulationNatural isolatesAnopheles gambiae
2017
Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae
Gómez-Díaz E, Yerbanga R, Lefèvre T, Cohuet A, Rowley M, Ouedraogo J, Corces V. Epigenetic regulation of Plasmodium falciparum clonally variant gene expression during development in Anopheles gambiae. Scientific Reports 2017, 7: 40655. PMID: 28091569, PMCID: PMC5238449, DOI: 10.1038/srep40655.Peer-Reviewed Original ResearchConceptsAP2 transcription factorsVar genesTranscription factorsAntisense long non-coding RNAProtein-coding transcriptsSingle var geneLong non-coding RNAsVariant gene expressionNon-coding RNAsVar gene transcriptionChromatin statePhenotypic plasticityHistone modificationsMultigene familyEpigenetic regulationAntisense lncRNAsGene transcriptionAnopheles gambiaeGene expressionIntraerythrocytic cycleMosquito hostSporogonic developmentTranscriptionParasite developmentGenes