2023
eQTL studies: from bulk tissues to single cells
Zhang J, Zhao H. eQTL studies: from bulk tissues to single cells. Journal Of Genetics And Genomics 2023, 50: 925-933. PMID: 37207929, PMCID: PMC10656365, DOI: 10.1016/j.jgg.2023.05.003.Peer-Reviewed Original ResearchConceptsExpression quantitative trait lociBulk tissueIdentification of eQTLContext-dependent gene regulationCell typesQuantitative trait lociMost eQTL studiesSingle cellsComplex traitsGene regulationEQTL studiesFunctional genesTrait lociSpecific genesChromosomal regionsDynamic regulationGene expressionBiological processesDifferent tissuesGenetic variantsExpression levelsDisease mechanismsGenesRegulationRecent studies
2019
O2‐10‐03: LEVERAGING TISSUE SPECIFIC GENE EXPRESSION REGULATION TO IDENTIFY GENES ASSOCIATED WITH ALZHEIMER'S DISEASE
Liu W, Li M, Zhang W, Zhou G, Wu X, Wang J, Zhao H. O2‐10‐03: LEVERAGING TISSUE SPECIFIC GENE EXPRESSION REGULATION TO IDENTIFY GENES ASSOCIATED WITH ALZHEIMER'S DISEASE. Alzheimer's & Dementia 2019, 15: p564-p565. DOI: 10.1016/j.jalz.2019.06.4507.Peer-Reviewed Original Research
2005
Integrating mRNA Decay Information into Co-Regulation Study
Chen L, Zhao H. Integrating mRNA Decay Information into Co-Regulation Study. Journal Of Computer Science And Technology 2005, 20: 434-438. DOI: 10.1007/s11390-005-0434-1.Peer-Reviewed Original ResearchMRNA decay ratesTranscript amountsTranscription rateBioinformatics analysisTranscriptional regulatory networksCo-regulated genesRelative transcript amountsMRNA degradation ratesHigh-throughput technologiesGene regulationGenomic signalsRegulatory networksDifferent genesGene clusteringMRNA synthesisMRNA transcriptsDownstream analysisGenesDNAMotifSimilarity analysisTranscriptsRegulationIdentification
2001
Light Control of Arabidopsis Development Entails Coordinated Regulation of Genome Expression and Cellular Pathways
Ma L, Li J, Qu L, Hager J, Chen Z, Zhao H, Deng X. Light Control of Arabidopsis Development Entails Coordinated Regulation of Genome Expression and Cellular Pathways. The Plant Cell 2001, 13: 2589. DOI: 10.2307/3871521.Peer-Reviewed Original Research