2024
Estimating Cell-Type-Specific Gene Co-Expression Networks from Bulk Gene Expression Data with an Application to Alzheimer’s Disease
Su C, Zhang J, Zhao H. Estimating Cell-Type-Specific Gene Co-Expression Networks from Bulk Gene Expression Data with an Application to Alzheimer’s Disease. Journal Of The American Statistical Association 2024, 119: 811-824. PMID: 39280354, PMCID: PMC11394578, DOI: 10.1080/01621459.2023.2297467.Peer-Reviewed Original Research
2013
Guilt by rewiring: gene prioritization through network rewiring in Genome Wide Association Studies
Hou L, Chen M, Zhang CK, Cho J, Zhao H. Guilt by rewiring: gene prioritization through network rewiring in Genome Wide Association Studies. Human Molecular Genetics 2013, 23: 2780-2790. PMID: 24381306, PMCID: PMC3990172, DOI: 10.1093/hmg/ddt668.Peer-Reviewed Original ResearchConceptsGenome-wide association studiesWide association studyDisease-associated genesGWAS signalsNetwork rewiringAssociation studiesFunctional genomic informationGene expression networksCo-expression networkDisease-associated pathwaysExpression networksGene networksGenomic informationAssociation signalsGene prioritizationDisease genesDisease locusSusceptibility lociGenesAssociation principleRewiringDisease associationsLociMillions of candidatesDisease conditions