A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons
Ma Q, Srivastav SP, Gamez S, Dayama G, Feitosa-Suntheimer F, Patterson EI, Johnson RM, Matson EM, Gold AS, Brackney DE, Connor JH, Colpitts TM, Hughes GL, Rasgon JL, Nolan T, Akbari OS, Lau NC. A mosquito small RNA genomics resource reveals dynamic evolution and host responses to viruses and transposons. Genome Research 2021, 31: gr.265157.120. PMID: 33419731, PMCID: PMC7919454, DOI: 10.1101/gr.265157.120.Peer-Reviewed Original ResearchConceptsPIWI-interacting RNAsGenomic resourcesMosquito cell culturesSmall RNA regulatory pathwaysSmall RNA expression profilesPIWI pathway genesRNA regulatory pathwaysSatellite DNA repeatsSmall RNA profilesCapacity of mosquitoesRNA interference (RNAi) pathwayRNA expression profilesImportant mosquito speciesTransposon activityGenome integritySiRNA populationsDNA repeatsInterference pathwayCluster lociCell culturesEvolutionary dynamicsPathway genesRegulatory pathwaysMosquito cellsExpression profiles