Aedes aegyptiuses RNA interference in defense against Sindbis virus infection
Campbell C, Keene K, Brackney D, Olson K, Blair C, Wilusz J, Foy B. Aedes aegyptiuses RNA interference in defense against Sindbis virus infection. BMC Microbiology 2008, 8: 47. PMID: 18366655, PMCID: PMC2278134, DOI: 10.1186/1471-2180-8-47.Peer-Reviewed Original ResearchMeSH KeywordsAedesAlphavirus InfectionsAnimalsArgonaute ProteinsDNA-Binding ProteinsDrosophila ProteinsGastrointestinal TractGene Expression ProfilingReceptors, TNF-Related Apoptosis-Inducing LigandRNA InterferenceRNA-Induced Silencing ComplexRNA, Small InterferingSindbis VirusSurvival AnalysisConceptsVirus-dependent mannerAgo2 protein levelsVirus-specific siRNAsAnti-viral defense mechanismProtein levelsSINV infectionRNAi componentsAnti-viral defenseRNAi pathwayRNAi responseBlood-fed controlsSmall RNAsDsRNA injectionRecombinant Sindbis virusRNA interferenceTranscript levelsSindbis virus infectionSINV RNAMost populationsStrand RNAPathway activitySINV replicationRNAVirus interactionsDefense mechanisms