2005
Plasma Carotenoids, Retinol, and Tocopherols and Risk of Breast Cancer
Tamimi RM, Hankinson SE, Campos H, Spiegelman D, Zhang S, Colditz GA, Willett WC, Hunter DJ. Plasma Carotenoids, Retinol, and Tocopherols and Risk of Breast Cancer. American Journal Of Epidemiology 2005, 161: 153-160. PMID: 15632265, DOI: 10.1093/aje/kwi030.Peer-Reviewed Original ResearchConceptsLutein/zeaxanthinBreast cancerHealth StudyPlasma carotenoidsNurses' Health StudyBreast cancer riskCase-control studyBreast cancer etiologyNodal metastasisHighest quintileInvasive cancerLowest quintileBlood drawInverse associationCancer riskAlpha-tocopherolCancerCancer etiologyGamma-tocopherolWomenRetinolQuintileRiskRole of carotenoidsAssociation
2001
Population-based study of α- and γ-tocopherol in plasma and adipose tissue as biomarkers of intake in Costa Rican adults 1 , 2 , 3
El-Sohemy A, Baylin A, Ascherio A, Kabagambe E, Spiegelman D, Campos H. Population-based study of α- and γ-tocopherol in plasma and adipose tissue as biomarkers of intake in Costa Rican adults 1 , 2 , 3. American Journal Of Clinical Nutrition 2001, 74: 356-363. PMID: 11522560, DOI: 10.1093/ajcn/74.3.356.Peer-Reviewed Original ResearchConceptsAlpha-tocopherol intakeBiomarkers of intakeAdipose tissueGamma-tocopherolTissue concentrationsAlpha-tocopherolGamma-tocopherol intakeFood frequency questionnairePopulation-based studyDietary alpha-tocopherolAlpha-tocopherol concentrationsGamma-tocopherol concentrationsTissue biopsy samplesSupplement useVitamin supplementsBlood samplesBiopsy samplesVitamin EGood biomarkerUS dietSuitable biomarkersIntakePalm shorteningBiomarkersAdults 1
1994
Human adiposeα-tocopherol andγ-tocopherol kinetics during and after 1 y ofα-tocopherol supplementation
Handelman G, Epstein W, Peerson J, Spiegelman D, Machlin L, Dratz E. Human adiposeα-tocopherol andγ-tocopherol kinetics during and after 1 y ofα-tocopherol supplementation. American Journal Of Clinical Nutrition 1994, 59: 1025-1032. PMID: 8172086, DOI: 10.1093/ajcn/59.5.1025.Peer-Reviewed Original ResearchConceptsAlpha-tocopherol intakeAlpha-tocopherolGamma-tocopherolTocopherol/dLong-term useSupplement useTocopherol ratioNeedle biopsySupplementation periodSupplementation trialTocopherol supplementCross-sectional measurementsHuman AdiposeAdditional yearIntakeSupplementationConsistent decreaseSupplementsSubjectsBiopsyGammaTrials