2007
Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users
Mehta S, Lucas G, Astemborski J, Kirk G, Vlahov D, Galai N. Early immunologic and virologic responses to highly active antiretroviral therapy and subsequent disease progression among HIV-infected injection drug users. AIDS Care 2007, 19: 637-645. PMID: 17505924, DOI: 10.1080/09540120701235644.Peer-Reviewed Original ResearchConceptsInjection drug usersActive antiretroviral therapyRisk of progressionVirologic responseTreatment interruptionImmunologic responseAntiretroviral therapyCommunity-based injection drug usersDrug usersMultiple Cox regression analysisRecent outpatient visitYears of HAARTCox regression analysisInjection drug useNew AIDS diagnosesSubsequent disease progressionEarly responseHAART initiationHAART initiatorsHIV careOutpatient visitsCox regressionPrognostic valueAIDS diagnosisPoor response
2003
Feasibility of referring drug users from a needle exchange program into an addiction treatment program: Experience with a mobile treatment van and LAAM maintenance
Kuo I, Brady J, Butler C, Schwartz R, Brooner R, Vlahov D, Strathdee S. Feasibility of referring drug users from a needle exchange program into an addiction treatment program: Experience with a mobile treatment van and LAAM maintenance. Journal Of Substance Use And Addiction Treatment 2003, 24: 67-74. PMID: 12646332, DOI: 10.1016/s0740-5472(02)00343-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultBaltimoreCocaine-Related DisordersFeasibility StudiesFemaleHeroin DependenceHumansMaleMethadyl AcetateMobile Health UnitsNarcoticsNeedle-Exchange ProgramsReferral and ConsultationSeverity of Illness IndexSubstance Abuse Treatment CentersSubstance-Related DisordersTime FactorsTreatment OutcomeConceptsTreatment programLevomethadyl acetate hydrochlorideFirst-line treatmentEarly treatment responseNeedle exchange programsCocaine-positive urine testsDrug treatment programsAddiction treatment programsLAAM maintenanceAgonist therapyLine treatmentOpioid dependenceUrine testsTreatment responseDrug usersNEP attendersHeroin addictionProgram attendersAlcohol useSubscale scoresProgram entrySignificant reductionAttendersLAAM
2000
Improved Antioxidant Status Among HIV-Infected Injecting Drug Users on Potent Antiretroviral Therapy
Tang A, Smit E, Semba R, Shah N, Lyles C, Li D, Vlahov D. Improved Antioxidant Status Among HIV-Infected Injecting Drug Users on Potent Antiretroviral Therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 23: 321-326. DOI: 10.1097/00042560-200004010-00006.Peer-Reviewed Original ResearchConceptsHIV-positive IDUsHIV-negative IDUsAntiretroviral therapySerum antioxidant levelsLutein/zeaxanthinStudy subjectsART regimenAntioxidant levelsSerum levelsDrug usersProtease inhibitorsLow serum antioxidant levelsPotent antiretroviral therapyInjecting Drug UsersExcess oxidative stressOxidative stress levelsΒ-cryptoxanthinAlcohol intakeSerum antioxidantsDietary intakeAntioxidant statusSignificant overall differenceΑ-tocopherolSerum αDrug useImproved antioxidant status among HIV-infected injecting drug users on potent antiretroviral therapy.
Tang A, Smit E, Semba R, Shah N, Lyles C, Li D, Vlahov D. Improved antioxidant status among HIV-infected injecting drug users on potent antiretroviral therapy. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 23: 321-6. PMID: 10836754, DOI: 10.1097/00126334-200004010-00006.Peer-Reviewed Original ResearchConceptsHIV-positive IDUsHIV-negative IDUsAntiretroviral therapySerum antioxidant levelsLutein/zeaxanthinStudy subjectsART regimenAntioxidant levelsSerum levelsDrug usersProtease inhibitorsLow serum antioxidant levelsSerum alpha-tocopherol levelsAlpha-tocopherolPotent antiretroviral therapyAlpha-tocopherol levelsExcess oxidative stressOxidative stress levelsAlcohol intakeSerum antioxidantsDietary intakeAntioxidant statusSignificant overall differenceDrug useHIV
1999
Evaluating supervised haart in late-stage HIV among drug users: A preliminary report
Greenberg B, Berkman A, Thomas R, Hoos D, Finkelstein R, Astemborski J, Vlahov D. Evaluating supervised haart in late-stage HIV among drug users: A preliminary report. Journal Of Urban Health 1999, 76: 468-480. PMID: 10609596, PMCID: PMC3456696, DOI: 10.1007/bf02351504.Peer-Reviewed Original ResearchConceptsInjection drug usersResidential health care facilitiesViral load increaseViral loadDrug usersMean age 42 yearsHepatitis C virus antibodyHuman immunodeficiency virus (HIV) infectionActive antiretroviral therapyC virus antibodyTreatment-experienced patientsImmunodeficiency virus infectionAge 42 yearsHistory of dementiaLate-stage HIVHealth care facilitiesHIV/AIDSHCV seropositivityAntiretroviral therapyInitial CD4IDU populationRecord reviewSupervised therapyVirus antibodiesMedication administration
1998
Drug abuse treatment success among needle exchange participants.
Brooner R, Kidorf M, King V, Beilenson P, Svikis D, Vlahov D. Drug abuse treatment success among needle exchange participants. Public Health Reports 1998, 113 Suppl 1: 129-39. PMID: 9722818, PMCID: PMC1307735.Peer-Reviewed Original ResearchConceptsNeedle exchange programsOpioid agonist treatment programStandard referral groupTreatment programReferral groupBetter short-term treatment outcomesNew admissionsDrug useHuman immunodeficiency virus (HIV) transmissionShort-term treatment outcomesDrug abuse treatment clinicsGreater baseline severitySelf-reported drug useDrug abuse treatment programsUse of drugsReferral patientsClinical variablesBaseline severityIncidence rateTreatment successTreatment clinicsTreatment outcomesBaseline differencesTreatment responseOutcome measures
1994
My place, your place, and no place: Behavior settings as a risk factor for HIV‐related injection practices of drug users in Baltimore, Maryland
Latkin C, Mandell W, Vlahov D, Oziemkowska M, Knowlton A, Celentano D. My place, your place, and no place: Behavior settings as a risk factor for HIV‐related injection practices of drug users in Baltimore, Maryland. American Journal Of Community Psychology 1994, 22: 415-430. PMID: 7879749, DOI: 10.1007/bf02506873.Peer-Reviewed Original ResearchConceptsDrug usersInjecting Drug UsersHIV risk behaviorsDrug injection behaviorSpread of HIVHIV infectionRisk factorsContaminated needlesMother's residenceInjection practicesShooting galleriesRisk behaviorsInjection behaviorPrimary settingMost participantsHIVMultiple regression analysisRegression analysisSemipublic areasOwn residenceResidenceSettingNeedleOpen-ended interviewsBaltimore