2013
Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population
Manini A, Jacobs M, Vlahov D, Hurd Y. Opioid Receptor Polymorphism A118G Associated with Clinical Severity in a Drug Overdose Population. Journal Of Medical Toxicology 2013, 9: 148-154. PMID: 23318993, PMCID: PMC3648633, DOI: 10.1007/s13181-012-0286-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlternative SplicingAmino Acid SubstitutionBenzodiazepinesCohort StudiesDrug OverdoseFemaleFollow-Up StudiesGenetic Association StudiesGenetic Predisposition to DiseaseHeart ArrestHumansMaleNarcoticsPilot ProjectsPolymorphism, Single NucleotideProspective StudiesReceptors, Opioid, muRespiratory InsufficiencySeverity of Illness IndexSympathomimeticsUnited StatesConceptsAcute drug overdoseG variant alleleClinical severityVariant allelesEmergency departmentDrug overdoseSingle nucleotide polymorphismsConsecutive adult ED patientsHuman mu-opioid receptor geneReceptor single nucleotide polymorphismsWorse clinical severityAdult ED patientsObservational cohort studyUrban teaching hospitalMu-opioid receptor geneAbove single nucleotide polymorphismsCohort studyED patientsRespiratory arrestCardiac arrestClinical variablesAcute drugSevere outcomesTeaching hospitalBlood samples
2003
Feasibility of referring drug users from a needle exchange program into an addiction treatment program: Experience with a mobile treatment van and LAAM maintenance
Kuo I, Brady J, Butler C, Schwartz R, Brooner R, Vlahov D, Strathdee S. Feasibility of referring drug users from a needle exchange program into an addiction treatment program: Experience with a mobile treatment van and LAAM maintenance. Journal Of Substance Use And Addiction Treatment 2003, 24: 67-74. PMID: 12646332, DOI: 10.1016/s0740-5472(02)00343-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultBaltimoreCocaine-Related DisordersFeasibility StudiesFemaleHeroin DependenceHumansMaleMethadyl AcetateMobile Health UnitsNarcoticsNeedle-Exchange ProgramsReferral and ConsultationSeverity of Illness IndexSubstance Abuse Treatment CentersSubstance-Related DisordersTime FactorsTreatment OutcomeConceptsTreatment programLevomethadyl acetate hydrochlorideFirst-line treatmentEarly treatment responseNeedle exchange programsCocaine-positive urine testsDrug treatment programsAddiction treatment programsLAAM maintenanceAgonist therapyLine treatmentOpioid dependenceUrine testsTreatment responseDrug usersNEP attendersHeroin addictionProgram attendersAlcohol useSubscale scoresProgram entrySignificant reductionAttendersLAAM
1999
Evaluating supervised haart in late-stage HIV among drug users: A preliminary report
Greenberg B, Berkman A, Thomas R, Hoos D, Finkelstein R, Astemborski J, Vlahov D. Evaluating supervised haart in late-stage HIV among drug users: A preliminary report. Journal Of Urban Health 1999, 76: 468-480. PMID: 10609596, PMCID: PMC3456696, DOI: 10.1007/bf02351504.Peer-Reviewed Original ResearchConceptsInjection drug usersResidential health care facilitiesViral load increaseViral loadDrug usersMean age 42 yearsHepatitis C virus antibodyHuman immunodeficiency virus (HIV) infectionActive antiretroviral therapyC virus antibodyTreatment-experienced patientsImmunodeficiency virus infectionAge 42 yearsHistory of dementiaLate-stage HIVHealth care facilitiesHIV/AIDSHCV seropositivityAntiretroviral therapyInitial CD4IDU populationRecord reviewSupervised therapyVirus antibodiesMedication administration
1998
Drug abuse treatment success among needle exchange participants.
Brooner R, Kidorf M, King V, Beilenson P, Svikis D, Vlahov D. Drug abuse treatment success among needle exchange participants. Public Health Reports 1998, 113 Suppl 1: 129-39. PMID: 9722818, PMCID: PMC1307735.Peer-Reviewed Original ResearchConceptsNeedle exchange programsOpioid agonist treatment programStandard referral groupTreatment programReferral groupBetter short-term treatment outcomesNew admissionsDrug useHuman immunodeficiency virus (HIV) transmissionShort-term treatment outcomesDrug abuse treatment clinicsGreater baseline severitySelf-reported drug useDrug abuse treatment programsUse of drugsReferral patientsClinical variablesBaseline severityIncidence rateTreatment successTreatment clinicsTreatment outcomesBaseline differencesTreatment responseOutcome measures