1998
Vitamin A Supplementation and Human Immunodeficiency Virus Load in Injection Drug Users
Semba R, Lyles C, Margolick J, Caiaffa W, Farzadegan H, Cohn S, Vlahov D. Vitamin A Supplementation and Human Immunodeficiency Virus Load in Injection Drug Users. The Journal Of Infectious Diseases 1998, 177: 611-616. PMID: 9498439, DOI: 10.1086/514235.Peer-Reviewed Original ResearchConceptsCD4 lymphocyte countHigh-dose vitaminHIV loadInjection drug usersLymphocyte countDrug usersVitamin AHuman immunodeficiency virus (HIV) infectionPlacebo-controlled clinical trialHuman immunodeficiency virus loadImmunodeficiency virus infectionUse of vitaminsPlasma vitaminHIV replicationVirus loadClinical trialsVirus infectionClinical investigationRetinol equivalentsSupplementationRetinoic acid response elementVitaminWeeksAcid response elementCount
1997
Vitamin A levels and human immunodeficiency virus load in injection drug users.
Semba R, Farzadegan H, Vlahov D. Vitamin A levels and human immunodeficiency virus load in injection drug users. MSphere 1997, 4: 93-5. PMID: 9008289, PMCID: PMC170483, DOI: 10.1128/cdli.4.1.93-95.1997.Peer-Reviewed Original ResearchConceptsInjection drug usersInfectious viral loadHIV viral loadPlasma vitaminViral loadDrug usersHuman immunodeficiency virus (HIV) infectionPeripheral blood mononuclear cellsHuman immunodeficiency virus loadHigher vertical transmissionLow plasma vitaminImmunodeficiency virus infectionIndependent risk factorProspective cohort studyBlood mononuclear cellsEntire study populationCross-sectional studyHIV loadQuantitative microcultureCohort studyHIV infectionMononuclear cellsRisk factorsVirus loadLow vitamin
1993
Increased Mortality Associated With Vitamin A Deficiency During Human Immunodeficiency Virus Type 1 Infection
Semba R, Graham N, Caiaffa W, Margolick J, Clement L, Vlahov D. Increased Mortality Associated With Vitamin A Deficiency During Human Immunodeficiency Virus Type 1 Infection. JAMA Internal Medicine 1993, 153: 2149-2154. PMID: 8379807, DOI: 10.1001/archinte.1993.00410180103012.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1 (HIV-1) infectionHIV-1-seropositive individualsVirus type 1 infectionCD4 T cellsHIV-1 infectionType 1 infectionPlasma vitaminT cellsHIV-1-seronegative individualsMean plasma vitaminLow CD4 levelsIntravenous drug usersHIV-seropositive participantsBlood cell countImportant risk factorNormal immune functionMumol/LCD4 levelsSeronegative individualsImmunologic statusSerologic markersClinical outcomesLiver diseaseSeropositive individualsIncreased Mortality