2000
Use of buprenorphine in HIV-infected injection drug users: negligible impact on virologic response to HAART
Carrieri M, Vlahov D, Dellamonica P, Gallais H, Lepeu G, Spire B, Obadia Y, Group T. Use of buprenorphine in HIV-infected injection drug users: negligible impact on virologic response to HAART. Drug And Alcohol Dependence 2000, 60: 51-54. PMID: 10821989, DOI: 10.1016/s0376-8716(00)80007-1.Peer-Reviewed Original ResearchConceptsEfficacy of HAARTDrug usersBuprenorphine substitution treatmentViral load trendsActive antiretroviral therapyFrench cohort studyHIV viral loadUse of buprenorphineInjection drug usersVirologic responseAntiretroviral therapyCohort studyBuprenorphine treatmentTreatment initiationViral loadMaintenance treatmentPotential confoundersHAARTSubstitution treatmentBuprenorphineHIVIndividual treatmentPatientsTreatmentLinear regression models
1999
Sex Differences in Longitudinal Human Immunodeficiency Virus Type 1 RNA Levels among Seroconverters
Sterling T, Lyles C, Vlahov D, Astemborski J, Margolick J, Quinn T. Sex Differences in Longitudinal Human Immunodeficiency Virus Type 1 RNA Levels among Seroconverters. The Journal Of Infectious Diseases 1999, 180: 666-672. PMID: 10438353, DOI: 10.1086/314967.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virus type 1 RNA levelsHIV-1 seroconvertersSex differencesCopies/mLHIV-1 pathogenesisInjection drug usersCase-control studyTime of seroconversionCross-sectional studyCourse of infectionMale patientsRapid progressorsFemale patientsCopies/Drug usersMale controlsVirus levelsPatientsRNA levelsSeroconvertersWomenMenNonprogressorsSeroconversionProgressorsRelationship between HIV‐1 viral load and continued drug use in untreated infected injection drug users
CARRIERI M, TAMALET C, VLAHOV D, YAHI N, CHESNEY M, MOATTI J. Relationship between HIV‐1 viral load and continued drug use in untreated infected injection drug users. Addiction Biology 1999, 4: 197-202. PMID: 20575786, DOI: 10.1080/13556219971704.Peer-Reviewed Original ResearchRecent heroin injectionViral loadDrug useHeroin injectionHIV-1 plasma viral loadInfected injection drug usersHIV-1 viral loadHIV viral loadPlasma viral loadDevelopment of AIDSContinued drug useInjection drug usersLong-term progressionSelf-administered questionnaireAntiretroviral treatmentClinical stageClinical examinationMedical recordsOutpatient carePatientsDrug usersSerological assaysHospital departmentsLaboratory informationRisk practicesA prospective, community‐based evaluation of liver enzymes in individuals with hepatitis C after drug use
Inglesby T, Rai R, Astemborski J, Gruskin L, Nelson K, Vlahov D, Thomas D. A prospective, community‐based evaluation of liver enzymes in individuals with hepatitis C after drug use. Hepatology 1999, 29: 590-596. PMID: 9918940, DOI: 10.1002/hep.510290219.Peer-Reviewed Original ResearchConceptsSerum ALT levelsALT levelsALT valuesDrug usePrior illicit drug useSerum alanine transaminase levelsAlanine transaminase levelsNormal ALT valuesHepatitis C virusIllicit drug useImportant disease outcomesElevated ALTHepatitis CTransaminase levelsInitial visitLiver biopsyVisit variabilityC virusCommunity-based evaluationLiver enzymesDisease outcomeHCVPatientsMore visitsNatural historyAccess to antiretroviral treatment among French HIV infected injection drug users: the influence of continued drug use. MANIF 2000 Study Group.
Carrieri M, Moatti J, Vlahov D, Obadia Y, Reynaud-Maurupt C, Chesney M. Access to antiretroviral treatment among French HIV infected injection drug users: the influence of continued drug use. MANIF 2000 Study Group. Journal Of Epidemiology & Community Health 1999, 53: 4. PMID: 10326045, PMCID: PMC1756774, DOI: 10.1136/jech.53.1.4.Peer-Reviewed Original ResearchConceptsActive injection drug usersInjection drug usersAntiretroviral treatmentFrench HIVDrug useDrug usersFormer injection drug usersDetailed clinical historyPast drug useEx-IDUsIDU patientsClinical stageClinical historyAIDS careHospital careAIDS specialistsCell countNew treatmentsRisk behaviorsHospital departmentsLogistic regressionHIVPatientsPhysiciansTreatmentIdiopathic chronic fatigue and chronic fatigue syndrome: a comparison of two case-definitions.
Arpino C, Carrieri M, Valesini G, Pizzigallo E, Rovere P, Tirelli U, Conti F, Dialmi P, Barberio A, Rusconi N, Bosco O, Lazzarin A, Saracco A, Moro M, Vlahov D. Idiopathic chronic fatigue and chronic fatigue syndrome: a comparison of two case-definitions. Annali Dell Istituto Superiore Di Sanità 1999, 35: 435-41. PMID: 10721210.Peer-Reviewed Original ResearchConceptsChronic fatigue syndromeDefinition of CFSFatigue syndromeIdiopathic chronic fatigueNumber of patientsSymptoms of individualsAcute onsetSore throatSymptomatic onsetIdiopathic fatigueChronic fatigueInfectious processEligibility criteriaPatientsSyndromeSymptomsOnsetSignsLymphadenopathyPharyngitisFatigueCasesCriteriaIndividuals
1998
Correlates of infection control practices in dentistry
Gershon R, Karkashian C, Vlahov D, Grimes M, Spannhake E. Correlates of infection control practices in dentistry. American Journal Of Infection Control 1998, 26: 29-34. PMID: 9503110, DOI: 10.1016/s0196-6553(98)70058-6.Peer-Reviewed Original ResearchGenetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant
Winkler C, Modi W, Smith M, Nelson G, Wu X, Carrington M, Dean M, Honjo T, Tashiro K, Yabe D, Buchbinder S, Vittinghoff E, Goedert J, O'Brien T, Jacobson L, Detels R, Donfield S, Willoughby A, Gomperts E, Vlahov D, Phair J, Study A, Study H, Study M, Study M, Cohort S, O'Brien S. Genetic Restriction of AIDS Pathogenesis by an SDF-1 Chemokine Gene Variant. Science 1998, 279: 389-393. PMID: 9430590, DOI: 10.1126/science.279.5349.389.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultChemokine CXCL12ChemokinesChemokines, CXCCohort StudiesDisease ProgressionGenesGenetic VariationGenotypeHeterozygoteHIV InfectionsHIV-1HumansMaleMolecular Sequence DataOdds RatioPolymorphism, GeneticRacial GroupsReceptors, CCR2Receptors, CCR5Receptors, ChemokineReceptors, CXCR4Survival AnalysisT-LymphocytesConceptsSDF1-3'AGenetic restrictionRecessive protective effectOnset of AIDSAIDS Cohort StudyStromal-derived factorCohort studyImmunodeficiency syndromeAIDS pathogenesisHuman immunodeficiencyHIV-1Protective effectCommon polymorphismsReceptor variantsGene variantsPrincipal ligandAIDSHomozygous stateGenetic association analysisOnsetCD4CCR5PatientsGene transcriptsImmunodeficiency
1993
Prevalence and incidence of left ventricular dysfunction in patients with human immunodeficiency virus infection
Herskowitz A, Vlahov D, Willoughby S, Chaisson R, Schulman S, Neumann D, Baughman K. Prevalence and incidence of left ventricular dysfunction in patients with human immunodeficiency virus infection. The American Journal Of Cardiology 1993, 71: 955-958. PMID: 8465788, DOI: 10.1016/0002-9149(93)90913-w.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusCongestive heart failureLeft ventricular dysfunctionLV dysfunctionHeart failureVentricular dysfunctionConsecutive human immunodeficiency virusSymptomatic congestive heart failureHuman immunodeficiency virus (HIV) infectionCardiac contractile abnormalitiesHIV clinic populationLow CD4 countImmunodeficiency virus infectionClinical heart diseaseCD4 countHIV clinicHIV infectionContractile abnormalitiesImmunodeficiency virusRecent onsetClinic populationHeart diseaseCrude rateVirus infectionPatients
1991
Diagnosis and differentiation of HTLV-I and HTLV-II infection by enzyme immunoassays using synthetic peptides.
Viscidi R, Hill P, Li S, Cerny E, Vlahov D, Farzadegan H, Halsey N, Kelen G, Quinn T. Diagnosis and differentiation of HTLV-I and HTLV-II infection by enzyme immunoassays using synthetic peptides. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1991, 4: 1190-8. PMID: 1941526.Peer-Reviewed Original ResearchConceptsEnzyme immunoassayHTLV-IIAntibody reactivityPeptide enzyme immunoassayHTLV-II infectionEpidemiology of HTLVDifferentiation of HTLVMicrotiter plate enzyme immunoassaysPattern of reactivitySeronegative controlsEmergency departmentEnv peptidesPositive seraViral infectionNeurological diseasesHTLVSynthetic peptidesInfectionDrug abuseMajor envelope proteinEnvEnvelope proteinPatientsSerumAntibodies
1990
Variation in risk for falls by clinical department: implications for prevention.
Rohde J, Myers A, Vlahov D. Variation in risk for falls by clinical department: implications for prevention. Infection Control And Hospital Epidemiology 1990, 11: 521-4. PMID: 2230041, DOI: 10.1086/646085.Peer-Reviewed Original ResearchConceptsPatient daysFall rateClinical departmentsTotal patient daysInjury prevention programsAcute care hospitalsBed acute care hospitalRate of fallInpatient fallsOncology servicesMedical recordsRetrospective analysisAdult servicesPrevention programsOne-year periodPsychiatry departmentPatientsInjuryAdditional yearIncident reportsDepartmentAgeFallDaysHospitalVariation in Risk for Falls by Clinical Department: Implications for Prevention
Rohde J, Myers A, Vlahov D. Variation in Risk for Falls by Clinical Department: Implications for Prevention. Infection Control And Hospital Epidemiology 1990, 11: 521-524. DOI: 10.2307/30151319.Peer-Reviewed Original ResearchConceptsPatient daysFall rateClinical departmentsTotal patient daysInjury prevention programsAcute care hospitalsBed acute care hospitalRate of fallInpatient fallsOncology servicesMedical recordsRetrospective analysisAdult servicesPrevention programsOne-year periodPsychiatry departmentPatientsInjuryAdditional yearIncident reportsDepartmentAgeFallDaysHospitalEpidemiology of falls among patients in a rehabilitation hospital.
Vlahov D, Myers A, al-Ibrahim M. Epidemiology of falls among patients in a rehabilitation hospital. Archives Of Physical Medicine And Rehabilitation 1990, 71: 8-12. PMID: 2297314.Peer-Reviewed Original ResearchConceptsEpidemiology of fallsGroup of patientsDiagnosis of strokeLower extremity amputationNonambulatory statusConsiderable morbidityRepeat fallsAcute careExtremity amputationDescriptive epidemiologyRehabilitation hospitalRisk factorsBedfast patientsHigh riskRehabilitation facilityGeriatric settingsRehabilitation settingsPatientsOlder agePreventive measuresPurpose of preventionFirst fallEpidemiologyIncident reportsAge
1989
Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (hiv) epidemic in new york city
Novick D, Trigg H, Jarlais D, Friedman S, Vlahov D, Kreek M. Cocaine injection and ethnicity in parenteral drug users during the early years of the human immunodeficiency virus (hiv) epidemic in new york city. Journal Of Medical Virology 1989, 29: 181-185. PMID: 2614398, DOI: 10.1002/jmv.1890290307.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusParenteral drug usersHispanic patientsDrug usersHIV infectionHuman immunodeficiency virus (HIV) epidemicImmune deficiency syndromeMultiple logistic regressionUse of cocaineNew York CityWhite patientsBlack patientsLiver diseaseImmunodeficiency virusDeficiency syndromeHIV epidemicCocaine injectionHigh prevalencePatientsDrug useEtiologic agentMedical problemsLogistic regressionExtensive epidemicHeroinImmunological effects of HIV-1 infection on the humoral response to malaria in an African population.
Wabwire-Mangen F, Shiff C, Vlahov D, Kline R, Serwadda D, Sewankambo N, Mugerwa R, Quinn T. Immunological effects of HIV-1 infection on the humoral response to malaria in an African population. American Journal Of Tropical Medicine And Hygiene 1989, 41: 504-11. PMID: 2683820, DOI: 10.4269/ajtmh.1989.41.504.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdolescentAdultAnimalsAntibodies, ProtozoanAntigens, ProtozoanAntigens, SurfaceCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleHIV SeropositivityHIV-1HumansMalariaMaleMiddle AgedPlasmodiumPlasmodium falciparumPlasmodium malariaeProtozoan ProteinsUgandaConceptsHIV-1 infectionTrauma patientsClinical AIDSSeronegative patientsAntibody levelsHIV-1HIV-1-seronegative patientsHIV-1 seropositive patientsPolyclonal B cell activationCross-sectional studyHigh malaria transmissionB cell stimulationB cell activationSeropositive patientsImmunodeficiency syndromeMalaria antibodiesHumoral responseImmunological effectsSerological responseStudy groupPatientsCell activationMalaria transmissionControl populationLess antibody
1987
Routine surveillance for infections in nursing homes: Experience at two facilities
Vlahov D, Tenney J, Cervino K, Shamer D. Routine surveillance for infections in nursing homes: Experience at two facilities. American Journal Of Infection Control 1987, 15: 47-53. PMID: 3646856, DOI: 10.1016/0196-6553(87)90001-0.Peer-Reviewed Original ResearchConceptsNursing homesRoutine surveillanceEye infectionsGastrointestinal tractSpecial infection control measuresRespiratory tract infectionsInfection Surveillance ProgramInfection control measuresMaryland nursing homesInfection control programTract infectionsInfection definitionsIndividual patientsInfection controlInfectionSurveillance dataSurveillance programTractSurveillanceControl programsControl measuresHomePatientsPhysiciansProspective Microbiologic Surveillance in Control of Nosocomial Methicillin-Resistant Staphylococcus aureus
Walsh T, Vlahov D, Hansen S, Sonnenberg E, Khabbaz R, Gadacz T, Standiford H. Prospective Microbiologic Surveillance in Control of Nosocomial Methicillin-Resistant Staphylococcus aureus. Infection Control And Hospital Epidemiology 1987, 8: 7-14. PMID: 3102395, DOI: 10.1017/s0195941700066923.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusNew MRSA casesNosocomial methicillin-resistant Staphylococcus aureusMRSA casesTracheostomy siteMRSA outbreaksNew casesNosocomial MRSA outbreaksHospital-wide effortPMS programStaphylococcus aureusFrequency of casesMicrobiologic surveillanceInfection controlQuarterly costsEarly identificationSurveillance programThird outbreakPilot studyMicrobiological surveillance programPatientsPrompt detectionInfectionNew outbreaksMonths
1986
On Antibiotic Prophylaxis in Cardiac Surgery: A Risk Factor for Wound Infection
Lilienfeld D, Vlahov D, Tenney J, McLaughlin J. On Antibiotic Prophylaxis in Cardiac Surgery: A Risk Factor for Wound Infection. The Annals Of Thoracic Surgery 1986, 42: 670-674. PMID: 3789857, DOI: 10.1016/s0003-4975(10)64605-x.Peer-Reviewed Original ResearchConceptsCardiac surgeryWound infectionClindamycin prophylaxisMedian sternotomy wound infectionEfficacy of prophylaxisPenicillin-allergic patientsSternotomy wound infectionAdult cardiac proceduresOdds ratio estimatesAntibiotic prophylaxisSternotomy infectionsRetrospective studyCardiac proceduresInfected patientsClindamycin administrationRisk factorsRelative riskMaryland hospitalsProphylaxisPatientsAlternative antibioticsInfectionSurgeryEndocarditisStaphylococcus epidermidisCandidal Suppurative Peripheral Thrombophlebitis Recognition, Prevention, and Management
Walsh T, Bustamente C, Vlahov D, Standiford H. Candidal Suppurative Peripheral Thrombophlebitis Recognition, Prevention, and Management. Infection Control And Hospital Epidemiology 1986, 7: 16-22. PMID: 3633240, DOI: 10.1017/s0195941700063736.Peer-Reviewed Original ResearchConceptsPeripheral thrombophlebitisBroad-spectrum antibiotic therapyCatheter site careSegmental venous resectionIntravenous amphotericin BDuration of hospitalizationCandida speciesAcute care hospitalsNosocomial fungal infectionsSuppurative thrombophlebitisVenous resectionCatheter siteAntibiotic therapyPalpable cordRisk factorsSite careCandidal colonizationRational therapyPatientsAmphotericin BBacterial infectionsThrombophlebitisFungal infectionsTherapyInfection
1985
Wide variation in risk of wound infection following clean neurosurgery. Implications for perioperative antibiotic prophylaxis.
Tenney J, Vlahov D, Salcman M, Ducker T. Wide variation in risk of wound infection following clean neurosurgery. Implications for perioperative antibiotic prophylaxis. Journal Of Neurosurgery 1985, 62: 243-7. PMID: 3968563, DOI: 10.3171/jns.1985.62.2.0243.Peer-Reviewed Original ResearchConceptsDeep wound infectionPerioperative antibiotic prophylaxisPostoperative wound infectionWound infectionAntibiotic prophylaxisClean neurosurgeryDeep wound infection rateClean neurosurgical proceduresWound infection rateClean neurosurgical operationsPerioperative antibioticsSuch prophylaxisRepeat operationHigh-risk operationsRecurrent gliomaInfection ratePotential efficacyProphylaxisGreater riskInfectionNeurosurgical proceduresNeurosurgical operationsOverall ratePatientsCraniotomy