2008
Modeling the Potential Impact of a Prescription Drug Copayment Increase on the Adult Asthmatic Medicaid Population
Bae SJ, Paltiel AD, Fuhlbrigge AL, Weiss ST, Kuntz KM. Modeling the Potential Impact of a Prescription Drug Copayment Increase on the Adult Asthmatic Medicaid Population. Value In Health 2008, 11: 110-118. PMID: 18237365, PMCID: PMC3476042, DOI: 10.1111/j.1524-4733.2007.00219.x.Peer-Reviewed Original ResearchMeSH KeywordsAdrenal Cortex HormonesAdultAge FactorsAnti-Asthmatic AgentsAsthmaCost SharingDrug PrescriptionsHealth Services AccessibilityHumansInsurance, Pharmaceutical ServicesMassachusettsMedicaidModels, EconometricNebulizers and VaporizersOutcome Assessment, Health CareState Health PlansTreatment RefusalUnited StatesConceptsFrequent acute exacerbationsAcute exacerbationCopayment increaseHealth outcomesPrescription drug copaymentsLikely health outcomesDrug nonadherenceCorticosteroid useAdult asthmaticsAcute eventDrug utilizationMedicaid populationDrug copaymentsMedicaid beneficiariesPrescription drugsCopaymentsReimbursement ratesFinancial burdenExacerbationTarget populationFirst yearNet savingsOutcomesPharmacyCommonwealth of Massachusetts
2007
Cost-effectiveness of omalizumab in adults with severe asthma: Results from the Asthma Policy Model
Wu AC, Paltiel AD, Kuntz KM, Weiss ST, Fuhlbrigge AL. Cost-effectiveness of omalizumab in adults with severe asthma: Results from the Asthma Policy Model. Journal Of Allergy And Clinical Immunology 2007, 120: 1146-1152. PMID: 17904628, PMCID: PMC3476046, DOI: 10.1016/j.jaci.2007.07.055.Peer-Reviewed Original ResearchConceptsQuality-adjusted life yearsCost-effectiveness ratioSevere asthmaEvent ratesSevere allergic asthmaQuality-adjusted monthsAllergic asthmaMost patientsAlternative medicationsHigher acquisition costUS FoodAsthmaDrug AdministrationLife yearsPatientsIncremental costDisease managementOmalizumabCost-effective optionTreatmentAcquisition costsEconomic outcomesCorticosteroidsMedicationsClinicians
2006
Forced Expiratory Volume in 1 Second Percentage Improves the Classification of Severity Among Children With Asthma
Fuhlbrigge AL, Weiss ST, Kuntz KM, Paltiel AD. Forced Expiratory Volume in 1 Second Percentage Improves the Classification of Severity Among Children With Asthma. Pediatrics 2006, 118: e347-e355. PMID: 16864642, DOI: 10.1542/peds.2005-2962.Peer-Reviewed Original ResearchMeSH KeywordsAlbuterolAnti-Asthmatic AgentsAsthmaBronchial Provocation TestsBronchodilator AgentsBudesonideChildChild, PreschoolCohort StudiesDouble-Blind MethodEmergency Service, HospitalEthnicityFemaleFollow-Up StudiesForced Expiratory VolumeHospitalizationHumansMaleMethacholine ChlorideModels, TheoreticalMulticenter Studies as TopicNedocromilRandomized Controlled Trials as TopicRiskSeverity of Illness IndexSpirometryTreatment OutcomeConceptsSerious asthma exacerbationsImportant clinical outcomesHealth care utilizationPrebronchodilator FEV1Asthma exacerbationsAsthma symptomsExpiratory volumeCare utilizationClinical outcomesSecond percentageAsthma health statusAsthma severity classificationAsthma-related eventsChildhood Asthma Management ProgramEpisode-free daysNational Asthma EducationAsthma-related hospitalizationsPrevention Program guidelinesMean symptom scoreAsthma Management ProgramFuture adverse eventsOutcomes of interestMultivariate regression analysisPopulation of childrenClassification of severityCost-effectiveness of inhaled steroids in asthma: Impact of effect on bone mineral density
Fuhlbrigge AL, Bae SJ, Weiss ST, Kuntz KM, Paltiel AD. Cost-effectiveness of inhaled steroids in asthma: Impact of effect on bone mineral density. Journal Of Allergy And Clinical Immunology 2006, 117: 359-366. PMID: 16461137, DOI: 10.1016/j.jaci.2005.10.036.Peer-Reviewed Original Research
2005
Surveillance for isocyanate asthma: a model based cost effectiveness analysis
Wild DM, Redlich CA, Paltiel AD. Surveillance for isocyanate asthma: a model based cost effectiveness analysis. Occupational And Environmental Medicine 2005, 62: 743. PMID: 16234399, PMCID: PMC1740898, DOI: 10.1136/oem.2004.016147.Peer-Reviewed Original Research
2004
A Single Measure of FEV1 Is Associated With Risk of Asthma Attacks in Long-term Follow-up
Kitch BT, Paltiel AD, Kuntz KM, Dockery DW, Schouten JP, Weiss ST, Fuhlbrigge AL. A Single Measure of FEV1 Is Associated With Risk of Asthma Attacks in Long-term Follow-up. CHEST Journal 2004, 126: 1875-1882. PMID: 15596687, DOI: 10.1378/chest.126.6.1875.Peer-Reviewed Original ResearchConceptsSubsequent asthma attacksAsthma attacksAsthma severityUS cohortNetherlands cohortUse of spirometryClinical practice guidelinesLongitudinal cohort studyAssociated shortnessObjective measuresAsthma careAsthma outcomesCohort studyCurrent smokingIndependent predictorsAdverse outcomesPractice guidelinesCohortLittle dataFEV1RiskSubjectsSeverityOutcomesSpirometryAssociation between preference-based health-related quality of life and asthma severity
Moy ML, Fuhlbrigge AL, Blumenschein K, Chapman RH, Zillich AJ, Kuntz KM, Paltiel AD, Kitch BT, Weiss ST, Neumann PJ. Association between preference-based health-related quality of life and asthma severity. Annals Of Allergy Asthma & Immunology 2004, 92: 329-334. PMID: 15049396, DOI: 10.1016/s1081-1206(10)61570-0.Peer-Reviewed Original ResearchConceptsPreference-based measuresHealth Utilities Index 3Standard gambleAsthma Symptom Utility IndexTime tradeoffPreference-based health-related qualityResource allocation decisionsHealth statesCost-effectiveness analysisStrength of preferenceSubject's health stateAllocation decisionsAsthma severityHealth-related qualityValues peoplePreference scoresPreference instrumentSymptom frequencyRating ScaleUtility indexAirway obstructionLung functionHUI3 scoresHealth improvementPreferences
2002
Impact of Site of Care, Race, and Hispanic Ethnicity on Medication Use for Childhood Asthma
Ortega AN, Gergen PJ, Paltiel AD, Bauchner H, Belanger KD, Leaderer BP. Impact of Site of Care, Race, and Hispanic Ethnicity on Medication Use for Childhood Asthma. Pediatrics 2002, 109: e1-e1. PMID: 11773569, DOI: 10.1542/peds.109.1.e1.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Asthmatic AgentsAsthmaBlack or African AmericanChild, PreschoolConnecticutDrug UtilizationFemaleHealth Care SurveysHealth Services AccessibilityHispanic or LatinoHumansInsurance, Physician ServicesMaleMassachusettsMultivariate AnalysisPractice Patterns, Physicians'Private PracticeQuality of Health CareRetrospective StudiesSocioeconomic FactorsWhite PeopleConceptsSite of careHispanic ethnicityMedication useInsurance statusPatient raceSymptom severityAsthma medication useBeta2-agonist usePrimary care contactsHispanic childrenPrimary care visitsPrivate practiceParent-reported questionnaire dataSystemic steroidsCare contactsCare visitsUrgent visitsChildhood asthmaSteroid useRegular providerPatient levelNational guidelinesMultivariate analysisMaternal educationSignificant associationA novel approach to defining the relationship between lung function and symptom status in asthma
Kuntz KM, Kitch BT, Fuhlbrigge AL, Paltiel AD, Weiss ST. A novel approach to defining the relationship between lung function and symptom status in asthma. Journal Of Clinical Epidemiology 2002, 55: 11-18. PMID: 11781117, DOI: 10.1016/s0895-4356(01)00412-7.Peer-Reviewed Original ResearchConceptsAsthma-related symptomsLung functionMean lung functionAverage baseline valuePopulation-wide basisExpiratory volumeSymptom daysSymptom scoresNighttime awakeningsSymptom statusClinical trialsMean changeBaseline valuesLinear regression analysisSymptomsRegression analysisNegative associationOverall improvementAssociationAsthmaConsistent relationshipTrials
2001
Use of Health Services by Insurance Status Among Children With Asthma
Ortega A, Belanger K, Paltiel A, Horwitz S, Bracken M, Leaderer B. Use of Health Services by Insurance Status Among Children With Asthma. Medical Care 2001, 39: 1065-1074. PMID: 11567169, DOI: 10.1097/00005650-200110000-00004.Peer-Reviewed Original ResearchConceptsPrimary care visitsHealth care useEmergency departmentInsurance statusCare visitsAsthmatic childrenMedication useCare useAsthma-related risk factorsRoutine primary care visitsProspective cohort studyHealth care visitsHealth care utilizationChildhood asthma severityPatient-provider communicationWhite childrenMedical DictionaryNew England hospitalsRace/ethnicityAsthma specialistCohort studyMedicaid childrenAsthma severityIndependent predictorsCare utilizationCost-effectiveness of inhaled corticosteroids in adults with mild-to-moderate asthma: Results from the Asthma Policy Model
Paltiel AD, Fuhlbrigge AL, Kitch BT, Liljas B, Weiss ST, Neumann PJ, Kuntz KM. Cost-effectiveness of inhaled corticosteroids in adults with mild-to-moderate asthma: Results from the Asthma Policy Model. Journal Of Allergy And Clinical Immunology 2001, 108: 39-in4. PMID: 11447380, DOI: 10.1067/mai.2001.116289.Peer-Reviewed Original ResearchConceptsSymptom-free daysCorticosteroid therapyAcute exacerbationModerate asthmaHealth-related qualityPopulation of patientsCost-effectiveness findingsHealth care costsCost-effectiveness analysisTotal health costsAdult asthmaObservational cohortRandomized trialsPatient preferencesPatient surveyClinical impactCorticosteroidsSide effectsCare costsDrug efficacyNatural historyAsthmaIncremental costTherapyMildFEV1 is associated with risk of asthma attacks in a pediatric population
Fuhlbrigge A, Kitch B, Paltiel A, Kuntz K, Neumann P, Dockery D, Weiss S. FEV1 is associated with risk of asthma attacks in a pediatric population. Journal Of Allergy And Clinical Immunology 2001, 107: 61-67. PMID: 11149992, DOI: 10.1067/mai.2001.111590.Peer-Reviewed Original ResearchConceptsNational Asthma EducationAsthma attacksAsthma outcomesAsthma educationOdds ratioAdverse asthma outcomesPrevention Program recommendationsSubsequent asthma attacksSelf-report groupSurvey 1 yearRespiratory QuestionnairePulmonary functionRetrospective cohortAsthma severityIndependent predictorsLung functionPediatric populationLung healthProportion of individualsPrevention programsStandard questionnaireMultivariate modelAssessment of riskStrong associationLongitudinal study