2017
Do Less Harm: Evaluating HIV Programmatic Alternatives in Response to Cutbacks in Foreign Aid.
Walensky RP, Borre ED, Bekker LG, Hyle EP, Gonsalves GS, Wood R, Eholié SP, Weinstein MC, Anglaret X, Freedberg KA, Paltiel AD. Do Less Harm: Evaluating HIV Programmatic Alternatives in Response to Cutbacks in Foreign Aid. Annals Of Internal Medicine 2017, 167: 618-629. PMID: 28847013, PMCID: PMC5675810, DOI: 10.7326/m17-1358.Peer-Reviewed Original ResearchConceptsYears of lifeHIV transmissionHIV programsFuture incident casesSecond-line ARTHIV care continuumViral load monitoringAdverse clinical consequencesResource-limited nationsBase-case analysisCurrent standardHIV deathsIncident casesCôte d'IvoireCare continuumART efficacyClinical consequencesHIV detectionLess HarmHIVSocietal perspectiveProductivity costsNational InstituteDeathYearsA Flow-Based Model of the HIV Care Continuum in the United States
Gonsalves GS, Paltiel AD, Cleary PD, Gill MJ, Kitahata MM, Rebeiro PF, Silverberg MJ, Horberg M, Abraham AG, Althoff KN, Moore R, Bosch RJ, Tang T, Hall HI, Kaplan EH. A Flow-Based Model of the HIV Care Continuum in the United States. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2017, 75: 548-553. PMID: 28471841, PMCID: PMC5533168, DOI: 10.1097/qai.0000000000001429.Peer-Reviewed Original ResearchConceptsViral suppressionAntiretroviral therapyHIV careNorth American AIDS Cohort CollaborationProportion of HIVHIV care continuumCohort CollaborationHIV diagnosisAntiretroviral treatmentVirological dataCare continuumFlow of patientsDisease controlPatientsCareAverage timeHIVTherapyLaboratory resultsMonthsSuppressionYearsDiagnosisIndividualsPrevention
2016
Cost-Effectiveness of Community-Based TB/HIV Screening and Linkage to Care in Rural South Africa
Gilbert JA, Shenoi SV, Moll AP, Friedland GH, Paltiel AD, Galvani AP. Cost-Effectiveness of Community-Based TB/HIV Screening and Linkage to Care in Rural South Africa. PLOS ONE 2016, 11: e0165614. PMID: 27906986, PMCID: PMC5131994, DOI: 10.1371/journal.pone.0165614.Peer-Reviewed Original ResearchConceptsTB/HIVTB/HIV controlHIV screeningHIV controlRural South AfricaLife yearsMonths of IPTMost life yearsHigh-incidence settingsWidespread prevalenceCost-effectiveness resultsProbabilistic sensitivity analysesHIV transmissionHigh burdenTreatment coverageUnknown patientsHIVHealthcare accessDrug resistanceActive casesMonthsLifetime usePatientsYearsScreeningOptimal frequency of rabies vaccination campaigns in Sub-Saharan Africa
Bilinski AM, Fitzpatrick MC, Rupprecht CE, Paltiel AD, Galvani AP. Optimal frequency of rabies vaccination campaigns in Sub-Saharan Africa. Proceedings Of The Royal Society B 2016, 283: 20161211. PMID: 27852799, PMCID: PMC5124087, DOI: 10.1098/rspb.2016.1211.Peer-Reviewed Original ResearchConceptsVaccination campaignRabies vaccination campaignsOptimal vaccination strategyPublic health benefitsWorld Health OrganizationVaccination strategiesRabies vaccinationVirus transmission modelDisease reintroductionSub-Saharan AfricaHealth OrganizationHealth benefitsRabies reintroductionRabiesNorthwest TanzaniaHuman deathsPrevious studiesVaccinationYearsDisease
2011
Dengue vector control strategies in an urban setting: an economic modelling assessment
Luz PM, Vanni T, Medlock J, Paltiel AD, Galvani AP. Dengue vector control strategies in an urban setting: an economic modelling assessment. The Lancet 2011, 377: 1673-1680. PMID: 21546076, PMCID: PMC3409589, DOI: 10.1016/s0140-6736(11)60246-8.Peer-Reviewed Original ResearchConceptsCost-effectiveness ratioHerd immunityAdult controlsDengue burdenIncremental cost-effectiveness ratioDengue transmissionCost-effective interventionResource-constrained countriesProbabilistic sensitivity analysesCost-effectiveness analysisIncidence of dengueFuture dengue epidemicsImmunological effectsHealth burdenRisk of dengueVector control policiesDengue epidemicsImmunityVector control strategiesBurdenDengueAdult mosquitoesInterventionEpidemicYears
2010
Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission
Andersson KM, Owens DK, Paltiel AD. Scaling Up Circumcision Programs in Southern Africa: The Potential Impact of Gender Disparities and Changes in Condom Use Behaviors on Heterosexual HIV Transmission. AIDS And Behavior 2010, 15: 938-948. PMID: 20924783, PMCID: PMC3112296, DOI: 10.1007/s10461-010-9784-y.Peer-Reviewed Original ResearchConceptsHeterosexual HIV transmissionCircumcision programsCondom useHIV infectionHIV transmissionRisk reduction counselingNew HIV infectionsMale condom useUncircumcised malesPrevention programsPopulation-level impactCondom use behaviorSexual partnershipsSafer sexCircumcisionMale transmissionInfectionCompartmental epidemic modelWomenSignificant benefitsGender disparitiesUse behaviorsYears