1998
Differential susceptibility of tracheal contraction to nonadrenergic noncholinergic relaxation.
Thompson D, Altiere R. Differential susceptibility of tracheal contraction to nonadrenergic noncholinergic relaxation. Journal Of Pharmacology And Experimental Therapeutics 1998, 284: 19-24. PMID: 9435155.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsElectric StimulationGuinea PigsHistamineIn Vitro TechniquesMaleMuscle ContractionNeural InhibitionNitric OxideOvalbuminTracheaVasoactive Intestinal PeptideConceptsAirway smooth muscle contractionSmooth muscle contractionInduction of toneMuscle contractionNerve stimulationNitric oxide-dependent componentAirway smooth muscle toneNitric oxide synthase inhibitorOvalbumin-sensitized guinea pigsNerve-induced relaxationNonadrenergic noncholinergic relaxationElectrical field stimulationOxide synthase inhibitorSmooth muscle toneLevel of toneNoncholinergic relaxationTracheal contractionRelaxant responsesContractile actionAirway tissueNerve activationContractile agonistsMuscle toneField stimulationSynthase inhibitor
1990
Enzymatic Modulation of Vasoactive Intestinal Peptide and Nonadrenergic Noncholinergic Inhibitory Responses in Guinea Pig Tracheae
Thompson D, Diamond L, Altiere R. Enzymatic Modulation of Vasoactive Intestinal Peptide and Nonadrenergic Noncholinergic Inhibitory Responses in Guinea Pig Tracheae. American Journal Of Respiratory And Critical Care Medicine 1990, 142: 1119-1123. PMID: 2240834, DOI: 10.1164/ajrccm/142.5.1119.Peer-Reviewed Original ResearchConceptsVasoactive intestinal peptideNANC inhibitory responsesGuinea pig tracheaConcentration-response curvesInhibitory responsesIntestinal peptideInhibitory systemPig tracheaNonadrenergic noncholinergic inhibitory responsesVIP concentration-response curveExogenous vasoactive intestinal peptideRelaxation responseExogenous VIP administrationNANC inhibitory neurotransmitterNANC nerve stimulationNANC relaxation responsesNoncholinergic inhibitory responsesElectrical field stimulationSoybean trypsin inhibitorAdrenergic inhibitoryTachykinin depletionCholinergic excitatoryVIP administrationAutonomic nervesNerve stimulation
1988
The effects of antagonists of vasoactive intestinal peptide on nonadrenergic noncholinergic inhibitory responses in feline airways
Thompson D, Altiere R, Diamond L. The effects of antagonists of vasoactive intestinal peptide on nonadrenergic noncholinergic inhibitory responses in feline airways. Peptides 1988, 9: 443-447. PMID: 3131749, DOI: 10.1016/0196-9781(88)90284-7.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholineAnimalsBronchiCatsElectric StimulationGrowth Hormone-Releasing HormoneIn Vitro TechniquesKineticsNorepinephrineSermorelinVasoactive Intestinal PeptideConceptsIntrapulmonary bronchiInhibitory responsesNonadrenergic noncholinergic inhibitory responsesEffective competitive antagonistNANC inhibitory responsesNANC relaxation responsesNoncholinergic inhibitory responsesRole of VIPVIP receptor antagonistVasoactive intestinal peptideEffects of antagonistsHigher VIP concentrationsVIP concentrationsVIP antagonistFeline airwaysIntestinal peptideReceptor antagonistVIP receptorsCompetitive antagonistNervous stimulationAntagonistRelaxation responseVIPGRFResponse