Evaluation of Dried Blood and Cerebrospinal Fluid Filter Paper Spots for Storing and Transporting Clinical Material for the Molecular Diagnosis of Invasive Meningococcal Disease
Kwambana-Adams B, Clark S, Tay N, Agbla S, Chaguza C, Kagucia E, Borrow R, Heyderman R. Evaluation of Dried Blood and Cerebrospinal Fluid Filter Paper Spots for Storing and Transporting Clinical Material for the Molecular Diagnosis of Invasive Meningococcal Disease. International Journal Of Molecular Sciences 2022, 23: 11879. PMID: 36233182, PMCID: PMC9569512, DOI: 10.3390/ijms231911879.Peer-Reviewed Original ResearchConceptsInvasive meningococcal diseaseMeningococcal diseaseNeisseria meningitidis infectionResource-limited settingsLow-resource settingsFilter paper spotsMeningococcal infectionReal-time PCRCerebrospinal fluidClinical specimensSubset of specimensBlood spotsSpot assayAntimicrobial resistanceBloodMolecular diagnosisClonal complexesClinical materialPaper spotsWhole-genome sequencingDBSInfectionSequence typesDiseaseDiagnosis